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The map label for this gene is fecD [C]

Identifier: 157368791

GI number: 157368791

Start: 604294

End: 605298

Strand: Reverse

Name: fecD [C]

Synonym: Spro_0546

Alternate gene names: 157368791

Gene position: 605298-604294 (Counterclockwise)

Preceding gene: 157368792

Following gene: 157368790

Centisome position: 11.11

GC content: 58.11

Gene sequence:

>1005_bases
ATGTCGGAAAAAATGCGTTTCAGGCTGGCATGGACAGTCGCCCCACTGTTGCTGGCAGGGTTGATGTTCGCCAATGTCGC
ACAAGGCAGCGTGTCGCTCTCTTTCTCTCAGGTGGTGACCGCACTGGGTATCACCCCTGGCGAAGTGCCGCCGATGATTA
AAAGTATTGTGCTGGATCTGCGGCTGCCCCGCACGCTGCTGGGATTACTGGCCGGTGCCGGGCTGGCGCTGGTCGGGGCG
CTATTACAAACCACCACCCGCAATGACCTGGCCGATCCTTTCCTGTTCGGCCTTTCCTCCGGTGCCTCTGCCGGCGTGGT
CATGGTCATTACCCGCCTCGGTAATAGCCTCGGGGCCTGGGCCTTACCGGTGTCTTCTTTTGTCGGTGGGATACTCTCCG
CTGCGGTGGTGATGATTATTTTTATGACTCAATCGCAGAAAGGCACCGATAAACTGATTATCTGTGGCCTGGCGGTCTCT
TTTTTATTCGGGGCCTTCACCAATTATCTGGTGTTTTCCGGCGATCAACGCACCGCCAGCAGCGTGCTGTTCTGGACGCT
GGGCGGGCTGGGGCTGGCGCGTTGGGACAATTTGATTTTTGCCTTGCTGGCGCTACTGATACTGGTGGTATTGATTGCCT
TGCGCTGGCGATCGCTGGATGGCTTGCTGGCGGGCGAACAGACAGCAGGCACCCTGGGCATCAACACCAGCCGCTTACGC
ACCGAAGTCTTTCTGTGCTGTTCACTGGCGACCGCGTTACTGGTGGCATTAACCGGGGTGATTGGGTTTGTCGGTTTAAT
GGTTCCCCACCTGGCTCGCCCCTTTACCGGCGTACGTCACCGGCGTCTGCTGCCGTTGGTTGGCGTATTGGGTGCCGTAC
TGCTCTCTGCCGGTGACCTGCTCAGCCGGGTCATTACCGCGCCACAGGAACTGCCTATCGGCATTATTACTGCCGGTCTT
GGCGGTATTTTCGTGCTGGCCATTTTGCTACGACGAACCCAGTGA

Upstream 100 bases:

>100_bases
GTTATTTGAAATTGAAATATCAGGAGCTGACGCCGGGGCCGGTCAATATTGATGCCATCCAAAAACTGGCGCACGCCCTT
TACCCCGCAGCCTTTACCTA

Downstream 100 bases:

>100_bases
TCGCCAATTGATATGGCCTGTCTCTAAAGGCCACCAGCCAATCGATTGCGAAAGGGCAAAAAACGGCGCTTTAGCGCTTG
CAGTGATCAAAAGCGCGAGT

Product: transport system permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MSEKMRFRLAWTVAPLLLAGLMFANVAQGSVSLSFSQVVTALGITPGEVPPMIKSIVLDLRLPRTLLGLLAGAGLALVGA
LLQTTTRNDLADPFLFGLSSGASAGVVMVITRLGNSLGAWALPVSSFVGGILSAAVVMIIFMTQSQKGTDKLIICGLAVS
FLFGAFTNYLVFSGDQRTASSVLFWTLGGLGLARWDNLIFALLALLILVVLIALRWRSLDGLLAGEQTAGTLGINTSRLR
TEVFLCCSLATALLVALTGVIGFVGLMVPHLARPFTGVRHRRLLPLVGVLGAVLLSAGDLLSRVITAPQELPIGIITAGL
GGIFVLAILLRRTQ

Sequences:

>Translated_334_residues
MSEKMRFRLAWTVAPLLLAGLMFANVAQGSVSLSFSQVVTALGITPGEVPPMIKSIVLDLRLPRTLLGLLAGAGLALVGA
LLQTTTRNDLADPFLFGLSSGASAGVVMVITRLGNSLGAWALPVSSFVGGILSAAVVMIIFMTQSQKGTDKLIICGLAVS
FLFGAFTNYLVFSGDQRTASSVLFWTLGGLGLARWDNLIFALLALLILVVLIALRWRSLDGLLAGEQTAGTLGINTSRLR
TEVFLCCSLATALLVALTGVIGFVGLMVPHLARPFTGVRHRRLLPLVGVLGAVLLSAGDLLSRVITAPQELPIGIITAGL
GGIFVLAILLRRTQ
>Mature_333_residues
SEKMRFRLAWTVAPLLLAGLMFANVAQGSVSLSFSQVVTALGITPGEVPPMIKSIVLDLRLPRTLLGLLAGAGLALVGAL
LQTTTRNDLADPFLFGLSSGASAGVVMVITRLGNSLGAWALPVSSFVGGILSAAVVMIIFMTQSQKGTDKLIICGLAVSF
LFGAFTNYLVFSGDQRTASSVLFWTLGGLGLARWDNLIFALLALLILVVLIALRWRSLDGLLAGEQTAGTLGINTSRLRT
EVFLCCSLATALLVALTGVIGFVGLMVPHLARPFTGVRHRRLLPLVGVLGAVLLSAGDLLSRVITAPQELPIGIITAGLG
GIFVLAILLRRTQ

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=277, Percent_Identity=37.1841155234657, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1790741, Length=291, Percent_Identity=34.020618556701, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786804, Length=309, Percent_Identity=31.7152103559871, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1788004, Length=289, Percent_Identity=31.4878892733564, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1786805, Length=284, Percent_Identity=34.1549295774648, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786347, Length=285, Percent_Identity=30.8771929824561, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35030; Mature: 34898

Theoretical pI: Translated: 11.50; Mature: 11.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKMRFRLAWTVAPLLLAGLMFANVAQGSVSLSFSQVVTALGITPGEVPPMIKSIVLDL
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
RLPRTLLGLLAGAGLALVGALLQTTTRNDLADPFLFGLSSGASAGVVMVITRLGNSLGAW
CCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHCCCCCHH
ALPVSSFVGGILSAAVVMIIFMTQSQKGTDKLIICGLAVSFLFGAFTNYLVFSGDQRTAS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCHHHH
SVLFWTLGGLGLARWDNLIFALLALLILVVLIALRWRSLDGLLAGEQTAGTLGINTSRLR
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
TEVFLCCSLATALLVALTGVIGFVGLMVPHLARPFTGVRHRRLLPLVGVLGAVLLSAGDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LSRVITAPQELPIGIITAGLGGIFVLAILLRRTQ
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEKMRFRLAWTVAPLLLAGLMFANVAQGSVSLSFSQVVTALGITPGEVPPMIKSIVLDL
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
RLPRTLLGLLAGAGLALVGALLQTTTRNDLADPFLFGLSSGASAGVVMVITRLGNSLGAW
CCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHCCCCCHH
ALPVSSFVGGILSAAVVMIIFMTQSQKGTDKLIICGLAVSFLFGAFTNYLVFSGDQRTAS
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCHHHH
SVLFWTLGGLGLARWDNLIFALLALLILVVLIALRWRSLDGLLAGEQTAGTLGINTSRLR
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
TEVFLCCSLATALLVALTGVIGFVGLMVPHLARPFTGVRHRRLLPLVGVLGAVLLSAGDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LSRVITAPQELPIGIITAGLGGIFVLAILLRRTQ
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]