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The map label for this gene is cysQ [H]

Identifier: 157368701

GI number: 157368701

Start: 503245

End: 503988

Strand: Direct

Name: cysQ [H]

Synonym: Spro_0454

Alternate gene names: 157368701

Gene position: 503245-503988 (Clockwise)

Preceding gene: 157368699

Following gene: 157368703

Centisome position: 9.24

GC content: 57.12

Gene sequence:

>744_bases
ATGATGTTAGAGCAAATTTGCCAACTGTCCCGCGAGGCGGGCGCAGCGATCATGGCGGTATATGACGGTAAACAACCGCT
TGATGTCGCACAGAAAAAAGATGATTCCCCGGTGACGGCGGCCGATCTGGCAGCGCACCACATTATCCAACGCGGCCTGG
CAGCGTTAACGCCGGAAATACCTTTACTGTCAGAAGAAGATCCACCGGGCTGGGAAGTGCGACAGAATTGGACGCGTTAC
TGGCTGGTCGATCCGCTGGACGGCACCAAGGAATTCCTCAATCGTAACGGCGAATTCACGGTAAATATTGCGTTGATTGA
AGACGGGCAGGCGGTGATGGGCGTGGTTTACGCCCCGGCGATCGACGTGTTGTACCTGGCCGAACGCGGCAAAGCCTGGA
AAGAAGAAAAGGGCCAACGTCAGGCGATTGGCGTCAGTAATGCCAATCCGCCGTTGGTGGTGGTTAGTCGCTCGCACAGT
GATGAAGAGCTGAAGGATTACCTGAATCAGTTAGGTGAGCATCAGACCGTATCTGTCGGTTCCTCGCTGAAGTTCTGCCT
GGTGGCAGAAGGTAAAGCGCAGCTTTACCCACGTTTTGGGCCGACCAATATCTGGGATACCGCCGCCGGACACGCGGTCG
CGGTGGCGGCCGGAGCGCAGATCCACGACTGGCAGGGCAGGCCGCTGCTCTATACGCCGCGTGAGTCTTTCCTCAACCCC
GGCTTCCGGGTTTCGCTGTTCTAA

Upstream 100 bases:

>100_bases
CGCGGGTTAAATCGTTGTGATGGATATTCCATGCAAAAAAAACTAGGCTGCTAGCAATGAGAAAGGGGAAATGACCCATG
GAACTGCATATCTGAGGTGA

Downstream 100 bases:

>100_bases
TTCAGTTTGCCAGCAGTTGGTGCAGTTGGGTCATGACCTGCTGCACCTCTTCCGGCGTCAGTGCGCCGTCTTTGGCAAAC
TGGATCCTGCCCTGCTTATC

Product: adenosine-3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MMLEQICQLSREAGAAIMAVYDGKQPLDVAQKKDDSPVTAADLAAHHIIQRGLAALTPEIPLLSEEDPPGWEVRQNWTRY
WLVDPLDGTKEFLNRNGEFTVNIALIEDGQAVMGVVYAPAIDVLYLAERGKAWKEEKGQRQAIGVSNANPPLVVVSRSHS
DEELKDYLNQLGEHQTVSVGSSLKFCLVAEGKAQLYPRFGPTNIWDTAAGHAVAVAAGAQIHDWQGRPLLYTPRESFLNP
GFRVSLF

Sequences:

>Translated_247_residues
MMLEQICQLSREAGAAIMAVYDGKQPLDVAQKKDDSPVTAADLAAHHIIQRGLAALTPEIPLLSEEDPPGWEVRQNWTRY
WLVDPLDGTKEFLNRNGEFTVNIALIEDGQAVMGVVYAPAIDVLYLAERGKAWKEEKGQRQAIGVSNANPPLVVVSRSHS
DEELKDYLNQLGEHQTVSVGSSLKFCLVAEGKAQLYPRFGPTNIWDTAAGHAVAVAAGAQIHDWQGRPLLYTPRESFLNP
GFRVSLF
>Mature_247_residues
MMLEQICQLSREAGAAIMAVYDGKQPLDVAQKKDDSPVTAADLAAHHIIQRGLAALTPEIPLLSEEDPPGWEVRQNWTRY
WLVDPLDGTKEFLNRNGEFTVNIALIEDGQAVMGVVYAPAIDVLYLAERGKAWKEEKGQRQAIGVSNANPPLVVVSRSHS
DEELKDYLNQLGEHQTVSVGSSLKFCLVAEGKAQLYPRFGPTNIWDTAAGHAVAVAAGAQIHDWQGRPLLYTPRESFLNP
GFRVSLF

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1790659, Length=246, Percent_Identity=74.390243902439, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI1788882, Length=234, Percent_Identity=25.6410256410256, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71995897, Length=264, Percent_Identity=26.1363636363636, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71995905, Length=264, Percent_Identity=26.1363636363636, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193202572, Length=241, Percent_Identity=26.1410788381743, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193202570, Length=243, Percent_Identity=26.7489711934156, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641722, Length=267, Percent_Identity=25.0936329588015, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI21357303, Length=234, Percent_Identity=23.9316239316239, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 27187; Mature: 27187

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLEQICQLSREAGAAIMAVYDGKQPLDVAQKKDDSPVTAADLAAHHIIQRGLAALTPEI
CCHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
PLLSEEDPPGWEVRQNWTRYWLVDPLDGTKEFLNRNGEFTVNIALIEDGQAVMGVVYAPA
CCCCCCCCCCCHHCCCCEEEEEECCCCHHHHHHCCCCCEEEEEEEEECCCCEEEEHHHHH
IDVLYLAERGKAWKEEKGQRQAIGVSNANPPLVVVSRSHSDEELKDYLNQLGEHQTVSVG
HHEEEEHHCCCCHHHHCCCEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEECC
SSLKFCLVAEGKAQLYPRFGPTNIWDTAAGHAVAVAAGAQIHDWQGRPLLYTPRESFLNP
CCEEEEEEECCCCEECCCCCCCCCCCCCCCCEEEEECCCEEECCCCCEEEECCHHHHCCC
GFRVSLF
CEEEEEC
>Mature Secondary Structure
MMLEQICQLSREAGAAIMAVYDGKQPLDVAQKKDDSPVTAADLAAHHIIQRGLAALTPEI
CCHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
PLLSEEDPPGWEVRQNWTRYWLVDPLDGTKEFLNRNGEFTVNIALIEDGQAVMGVVYAPA
CCCCCCCCCCCHHCCCCEEEEEECCCCHHHHHHCCCCCEEEEEEEEECCCCEEEEHHHHH
IDVLYLAERGKAWKEEKGQRQAIGVSNANPPLVVVSRSHSDEELKDYLNQLGEHQTVSVG
HHEEEEHHCCCCHHHHCCCEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEECC
SSLKFCLVAEGKAQLYPRFGPTNIWDTAAGHAVAVAAGAQIHDWQGRPLLYTPRESFLNP
CCEEEEEEECCCCEECCCCCCCCCCCCCCCCEEEEECCCEEECCCCCEEEECCHHHHCCC
GFRVSLF
CEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]