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The map label for this gene is hfq

Identifier: 157368678

GI number: 157368678

Start: 483169

End: 483477

Strand: Direct

Name: hfq

Synonym: Spro_0431

Alternate gene names: 157368678

Gene position: 483169-483477 (Clockwise)

Preceding gene: 157368677

Following gene: 157368679

Centisome position: 8.87

GC content: 50.16

Gene sequence:

>309_bases
ATGGCTAAGGGGCAATCTTTGCAAGATCCGTTCCTGAACGCATTGCGTCGTGAACGTGTTCCGGTTTCTATTTATTTGGT
GAATGGTATTAAGCTGCAAGGCCAGATTGAGTCTTTTGACCAGTTTGTCATCCTGTTGAAAAACACGGTGAGCCAGATGG
TTTATAAGCACGCTATCTCTACCGTTGTCCCGTCACGCCCGGTTTCGCACCATAGCAATACTCCGAGCGGCGGCACCAGT
AACTATCACCATGGTAACAACCCGTCTGCGCCGCAACAGCCGCAGCAGGAAAGCGATGACGCTGAATAA

Upstream 100 bases:

>100_bases
TACAATTGATGAGTATTCAGCGCGCAAATTTTTTAGGTCGTTTATTTTAGAGCCGACAGGTTCTTAGTTAAAAACAACAA
GCAAATAAGGAAAAGATAGA

Downstream 100 bases:

>100_bases
AGCGCGTTGCGAGTCAACCATGACGGGGAGCATAAGCAGCCGTGGGCTGTTTATGTCCCCCAAACTCACGGATTTCCGTT
TGAGAGGTTGCACGCTTGTT

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: HF-1; Host factor-I protein; HF-I

Number of amino acids: Translated: 102; Mature: 101

Protein sequence:

>102_residues
MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNTPSGGTS
NYHHGNNPSAPQQPQQESDDAE

Sequences:

>Translated_102_residues
MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNTPSGGTS
NYHHGNNPSAPQQPQQESDDAE
>Mature_101_residues
AKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNTPSGGTSN
YHHGNNPSAPQQPQQESDDAE

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=106, Percent_Identity=83.9622641509434, Blast_Score=171, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_SERP5 (A8G8U9)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001476667.1
- ProteinModelPortal:   A8G8U9
- SMR:   A8G8U9
- STRING:   A8G8U9
- GeneID:   5602862
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0431
- eggNOG:   COG1923
- HOGENOM:   HBG645207
- OMA:   KNTVTQM
- ProtClustDB:   PRK00395
- BioCyc:   SPRO399741:SPRO_0431-MONOMER
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 11266; Mature: 11134

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAIS
CCCCCCCCCHHHHHHHHCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
TVVPSRPVSHHSNTPSGGTSNYHHGNNPSAPQQPQQESDDAE
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAIS
CCCCCCCCHHHHHHHHCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
TVVPSRPVSHHSNTPSGGTSNYHHGNNPSAPQQPQQESDDAE
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA