Click here to switch to the map view.

The map label for this gene is katE [C]

Identifier: 157368624

GI number: 157368624

Start: 424320

End: 425852

Strand: Direct

Name: katE [C]

Synonym: Spro_0377

Alternate gene names: 157368624

Gene position: 424320-425852 (Clockwise)

Preceding gene: 157368623

Following gene: 157368625

Centisome position: 7.79

GC content: 47.75

Gene sequence:

>1533_bases
ATGAATCAGCGGGTATTAGTAAGTTCATTTATTCTTTCGGCAGTACTGACAGGTCTTCCCCAGGCAAATGCAGATCCCCA
AATGACCAACGATAATGGCTCCCCGGTTGGAGATAATCAGAACTCCCAAACGGCGGGCCCTAATGGGCCAACGCTGCTGC
AGGATGGGCATTTGATTCAGAAGCTTCAGCGCTTTGAACGCGAGCGTATTCCAGAGCGTGTCGTTCACGCCAGAGGAACC
GGTGCTTTTGGCGAGTTTAAGGCGGAGAAAGATATCAGCGATTTGACTCGTGCCGCCGTTTTTAAACCGGGGACCACTAC
GCCGGTTTTTGTTCGATTTTCTACGGTTATTCATCCGAAAGGATCTCCGGAGGAGTTACGGGACCCCCATGGCTTTGCCA
TTAAATTTTATACCACCCAGGGTAATTGGGATTTGGTGGGGTTAAGCCATGGAATCTTCTTTATCCGGGATGCGATGAAG
TTCCCCGATATGATTCATTCTCTGAAGCCCTCTCCGGTCACCAATGTTCAGGATCCCAATCGCTATTTTGATTTCTTTAG
CCATCAGCCTGAAAGTACCCACATGTTGACTCAAATTTTTTCATTCCGCGGTATACCGACCTCATACCGTAAAATGGATG
GCTGGGGGGTTCATGCATTTAAGTTTATTAATAAAAAAGGCGATGTGACTTATGTGAAATTTTACTTCAAGAGCCGCCAG
GGCGTTGAGGGCTATAACGACCATCAGGCACAGCTCGAACAAGGCAAAGATTTTAATAACTTAACTAACGATCTCTATAC
CAATATCAATAAGGGTAACAACCCGGTTTGGGATCTTTATATCCAAACCTTAAAGCCATCTCAGTTAAATGATTTCCGCT
TTAACCCGCTGGATGATACTAAATTATGGCTTGGCGTTCCTGAGACCAAAGTCGGTACTTTGACGCTTAATAAAGTTCCG
GATAACTACTTCCAGAGTACTGAGTCCGTGGCTTTTGACCCGTCAAATCTGGTCCCCGGCATTGAGCCTTCCGAGGACCG
CATGCTACAGGGACGACTTTTCTCCTATGCCGATGCCCATATGTATCGTCTGGGGGCAAACTATCAGCAAATCCCTATCA
ACCGACCGCGGGTTGCGGTACACAATGACAACCAGGACGGCAGAGGTAACCAGGGATCGACTAAAGGCGACATCAACTAT
CAGCCTTCTGTGGACGACGGTGCTCCGGTCGACAACGCGGAATATAAGGCAACCTCAGCACTGCTTGATGGCACCACCCA
ACAGAAAATCATCGCTAAGACCGATAACTTTGAGCAGGCTGGCATTTATTACCGTTCCTTAACCAAACCGCAGCAGTCTG
ATCTGATTGAGGCGCTCGGGAGCAACTTGAAATTGGTCAAAAATGCTCATGTACGGCAAACCATGCTGGGTTACTTCTAT
AAGGCAGACCCGGAGTATGGCACTCGCCTGGCGGAGTGGACCAAAGACAATGTTGAAGCTATCAAAGTATTGGCCGACAA
GCTGAAAGATTAA

Upstream 100 bases:

>100_bases
AACCAGCATAGTTTAGTTTTGCCTATTGGAACAATTACTGAGAGCTTTTTTAATTCTGGTAATATCTGTCCGGGTTAAAT
AAAAAACTAAGAGGCAAGCA

Downstream 100 bases:

>100_bases
CTGACCGGAGGCCGCCCTGCCGGGCGGCATAGCAATAATGAACAGTAGAATAATACGCCTCGCCGCGCTGGCCCTGTTAG
GGGGAGTGTGGTTTAGCACC

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MNQRVLVSSFILSAVLTGLPQANADPQMTNDNGSPVGDNQNSQTAGPNGPTLLQDGHLIQKLQRFERERIPERVVHARGT
GAFGEFKAEKDISDLTRAAVFKPGTTTPVFVRFSTVIHPKGSPEELRDPHGFAIKFYTTQGNWDLVGLSHGIFFIRDAMK
FPDMIHSLKPSPVTNVQDPNRYFDFFSHQPESTHMLTQIFSFRGIPTSYRKMDGWGVHAFKFINKKGDVTYVKFYFKSRQ
GVEGYNDHQAQLEQGKDFNNLTNDLYTNINKGNNPVWDLYIQTLKPSQLNDFRFNPLDDTKLWLGVPETKVGTLTLNKVP
DNYFQSTESVAFDPSNLVPGIEPSEDRMLQGRLFSYADAHMYRLGANYQQIPINRPRVAVHNDNQDGRGNQGSTKGDINY
QPSVDDGAPVDNAEYKATSALLDGTTQQKIIAKTDNFEQAGIYYRSLTKPQQSDLIEALGSNLKLVKNAHVRQTMLGYFY
KADPEYGTRLAEWTKDNVEAIKVLADKLKD

Sequences:

>Translated_510_residues
MNQRVLVSSFILSAVLTGLPQANADPQMTNDNGSPVGDNQNSQTAGPNGPTLLQDGHLIQKLQRFERERIPERVVHARGT
GAFGEFKAEKDISDLTRAAVFKPGTTTPVFVRFSTVIHPKGSPEELRDPHGFAIKFYTTQGNWDLVGLSHGIFFIRDAMK
FPDMIHSLKPSPVTNVQDPNRYFDFFSHQPESTHMLTQIFSFRGIPTSYRKMDGWGVHAFKFINKKGDVTYVKFYFKSRQ
GVEGYNDHQAQLEQGKDFNNLTNDLYTNINKGNNPVWDLYIQTLKPSQLNDFRFNPLDDTKLWLGVPETKVGTLTLNKVP
DNYFQSTESVAFDPSNLVPGIEPSEDRMLQGRLFSYADAHMYRLGANYQQIPINRPRVAVHNDNQDGRGNQGSTKGDINY
QPSVDDGAPVDNAEYKATSALLDGTTQQKIIAKTDNFEQAGIYYRSLTKPQQSDLIEALGSNLKLVKNAHVRQTMLGYFY
KADPEYGTRLAEWTKDNVEAIKVLADKLKD
>Mature_510_residues
MNQRVLVSSFILSAVLTGLPQANADPQMTNDNGSPVGDNQNSQTAGPNGPTLLQDGHLIQKLQRFERERIPERVVHARGT
GAFGEFKAEKDISDLTRAAVFKPGTTTPVFVRFSTVIHPKGSPEELRDPHGFAIKFYTTQGNWDLVGLSHGIFFIRDAMK
FPDMIHSLKPSPVTNVQDPNRYFDFFSHQPESTHMLTQIFSFRGIPTSYRKMDGWGVHAFKFINKKGDVTYVKFYFKSRQ
GVEGYNDHQAQLEQGKDFNNLTNDLYTNINKGNNPVWDLYIQTLKPSQLNDFRFNPLDDTKLWLGVPETKVGTLTLNKVP
DNYFQSTESVAFDPSNLVPGIEPSEDRMLQGRLFSYADAHMYRLGANYQQIPINRPRVAVHNDNQDGRGNQGSTKGDINY
QPSVDDGAPVDNAEYKATSALLDGTTQQKIIAKTDNFEQAGIYYRSLTKPQQSDLIEALGSNLKLVKNAHVRQTMLGYFY
KADPEYGTRLAEWTKDNVEAIKVLADKLKD

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=472, Percent_Identity=43.2203389830509, Blast_Score=364, Evalue=1e-101,
Organism=Escherichia coli, GI48994891, Length=472, Percent_Identity=37.5, Blast_Score=307, Evalue=8e-85,
Organism=Caenorhabditis elegans, GI71998444, Length=469, Percent_Identity=40.9381663113006, Blast_Score=349, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI25147792, Length=472, Percent_Identity=40.4661016949153, Blast_Score=347, Evalue=1e-95,
Organism=Caenorhabditis elegans, GI25151141, Length=478, Percent_Identity=40.3765690376569, Blast_Score=347, Evalue=1e-95,
Organism=Saccharomyces cerevisiae, GI6321525, Length=343, Percent_Identity=44.8979591836735, Blast_Score=290, Evalue=3e-79,
Organism=Saccharomyces cerevisiae, GI6320462, Length=358, Percent_Identity=43.854748603352, Blast_Score=286, Evalue=6e-78,
Organism=Drosophila melanogaster, GI17981717, Length=474, Percent_Identity=40.9282700421941, Blast_Score=351, Evalue=8e-97,
Organism=Drosophila melanogaster, GI19920968, Length=365, Percent_Identity=43.8356164383562, Blast_Score=336, Evalue=3e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 57442; Mature: 57442

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQRVLVSSFILSAVLTGLPQANADPQMTNDNGSPVGDNQNSQTAGPNGPTLLQDGHLIQ
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCHHHH
KLQRFERERIPERVVHARGTGAFGEFKAEKDISDLTRAAVFKPGTTTPVFVRFSTVIHPK
HHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHEECCCCCCEEEEEEEEEECCC
GSPEELRDPHGFAIKFYTTQGNWDLVGLSHGIFFIRDAMKFPDMIHSLKPSPVTNVQDPN
CCHHHHCCCCCEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
RYFDFFSHQPESTHMLTQIFSFRGIPTSYRKMDGWGVHAFKFINKKGDVTYVKFYFKSRQ
HHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEECCCCCEEEEEEEEECCC
GVEGYNDHQAQLEQGKDFNNLTNDLYTNINKGNNPVWDLYIQTLKPSQLNDFRFNPLDDT
CCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCC
KLWLGVPETKVGTLTLNKVPDNYFQSTESVAFDPSNLVPGIEPSEDRMLQGRLFSYADAH
EEEEECCCCCEEEEEECCCCCHHHHCCCCEEECHHHCCCCCCCCHHHHHHHHHHHHHHHH
MYRLGANYQQIPINRPRVAVHNDNQDGRGNQGSTKGDINYQPSVDDGAPVDNAEYKATSA
HHHCCCCCEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LLDGTTQQKIIAKTDNFEQAGIYYRSLTKPQQSDLIEALGSNLKLVKNAHVRQTMLGYFY
HHCCCCCCEEEEECCCCCHHCEEHHHCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHE
KADPEYGTRLAEWTKDNVEAIKVLADKLKD
ECCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNQRVLVSSFILSAVLTGLPQANADPQMTNDNGSPVGDNQNSQTAGPNGPTLLQDGHLIQ
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCHHHH
KLQRFERERIPERVVHARGTGAFGEFKAEKDISDLTRAAVFKPGTTTPVFVRFSTVIHPK
HHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHEECCCCCCEEEEEEEEEECCC
GSPEELRDPHGFAIKFYTTQGNWDLVGLSHGIFFIRDAMKFPDMIHSLKPSPVTNVQDPN
CCHHHHCCCCCEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
RYFDFFSHQPESTHMLTQIFSFRGIPTSYRKMDGWGVHAFKFINKKGDVTYVKFYFKSRQ
HHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEECCCCCEEEEEEEEECCC
GVEGYNDHQAQLEQGKDFNNLTNDLYTNINKGNNPVWDLYIQTLKPSQLNDFRFNPLDDT
CCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCC
KLWLGVPETKVGTLTLNKVPDNYFQSTESVAFDPSNLVPGIEPSEDRMLQGRLFSYADAH
EEEEECCCCCEEEEEECCCCCHHHHCCCCEEECHHHCCCCCCCCHHHHHHHHHHHHHHHH
MYRLGANYQQIPINRPRVAVHNDNQDGRGNQGSTKGDINYQPSVDDGAPVDNAEYKATSA
HHHCCCCCEECCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LLDGTTQQKIIAKTDNFEQAGIYYRSLTKPQQSDLIEALGSNLKLVKNAHVRQTMLGYFY
HHCCCCCCEEEEECCCCCHHCEEHHHCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHE
KADPEYGTRLAEWTKDNVEAIKVLADKLKD
ECCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]