Click here to switch to the map view.

The map label for this gene is rpoC

Identifier: 157368527

GI number: 157368527

Start: 317634

End: 321860

Strand: Direct

Name: rpoC

Synonym: Spro_0278

Alternate gene names: 157368527

Gene position: 317634-321860 (Clockwise)

Preceding gene: 157368526

Following gene: 157368535

Centisome position: 5.83

GC content: 53.92

Gene sequence:

>4227_bases
GTGAAAGACTTATTAAAGTTTCTGAAAGCGCAAACCAAGACCGAAGAGTTTGACGCGATCAAGATTGCTCTGGCATCGCC
AGACATGATCCGTTCCTGGTCGTTCGGCGAAGTCAAGAAGCCGGAAACCATTAACTACCGTACGTTCAAACCAGAACGTG
ACGGCCTTTTCTGCGCCCGTATCTTTGGGCCAGTAAAAGACTACGAGTGCCTGTGCGGTAAGTACAAGCGCTTAAAACAC
CGCGGCGTGATTTGTGAGAAGTGCGGCGTTGAAGTGACCCAGACCAAAGTACGCCGTGAGCGTATGGGGCACATCGAGCT
GGCTTCACCAACTGCGCACATCTGGTTCCTGAAATCGCTGCCATCCCGCATCGGTTTGCTGCTGGATATGCCGCTGCGTG
ACATCGAACGTGTACTGTACTTCGAATCCTATGTGGTTATCGAAGGCGGTATGACTAACCTCGAGCGTCGTCAGATCCTG
ACTGAAGAGCAGTATCTGGATGCGCTGGAAGAGTTCGGTGATGAATTCGACGCCAAGATGGGTGCGGAAGCTATTCAGGC
CCTGTTGAAAAACATGGATCTGGAGCAAGAGTGTGAAACTCTGCGCGAAGAGCTGAACGAAACCAACTCCGAAACCAAGC
GTAAGAAGCTGACCAAGCGTATCAAGCTGCTGGAAGCGTTCGTACAGTCTGGCAACAAGCCAGAGTGGATGATCCTGACC
GTGCTGCCGGTACTGCCACCGGATCTGCGTCCGCTGGTGCCGTTGGATGGGGGTCGTTTCGCGACTTCAGATCTGAACGA
TCTGTATCGCCGCGTGATCAACCGTAACAACCGTCTGAAACGCCTGCTGGATCTGGCTGCGCCTGACATCATCGTGCGCA
ACGAAAAGCGTATGCTGCAAGAAGCGGTAGATGCCCTGCTGGATAACGGCCGTCGCGGTCGTGCGATCACCGGTTCCAAC
AAGCGTCCTCTGAAATCTTTGGCCGATATGATCAAAGGTAAGCAGGGTCGCTTCCGTCAGAACCTGTTGGGTAAACGTGT
TGACTACTCTGGTCGTTCTGTAATCACCGTAGGTCCATACCTGCGTCTGCATCAGTGCGGTCTGCCTAAGAAAATGGCAC
TGGAGCTGTTCAAACCGTTCATCTACGGCAAGCTGGAACTGCGTGGCCTGGCCACCACCATCAAAGCCGCCAAGAAAATG
GTTGAGCGTGAAGAAGCTGTCGTTTGGGACATCCTGGACGAAGTTATCCGCGAACACCCGGTACTGCTGAACCGTGCACC
AACCCTGCACCGTTTGGGTATCCAGGCATTTGAACCGGTTCTGATCGAAGGTAAGGCTATCCAGCTGCACCCGCTGGTTT
GTGCGGCATACAACGCCGACTTCGATGGTGACCAAATGGCAGTACACGTTCCACTGACGCTTGAAGCTCAGCTGGAAGCG
CGTGCGCTGATGATGTCTACCAACAACATCCTGTCACCAGCGAACGGCGAGCCAATCATCGTTCCTTCTCAGGACGTTGT
ATTGGGTCTGTACTACATGACCCGTGACTGTGTTAACGCCAAAGGCGAAGGCATGGTGTTGAGTGGCCCGAAAGAAGCGG
AGCGTATTTACCGCGCCGGTCTGGCTTCTCTGCATGCGCGTGTCAAAGTGCGTATCACCGAAGAGATCAAAAACACCGAA
GGCGAGTCTGTACACCAGACTTCGATCGTCGACACTACCGTTGGTCGCGCCATCCTGTGGATGATCGTACCGCGCGGTCT
GCCGTATTCGATCGTTAACCAGCCTTTGGGCAAGAAAGCTATCTCCAAGATGCTGAACACCTGTTACCGCATCCTGGGCC
TGAAGCCGACCGTTATCTTTGCTGACCAGATCATGTACACCGGTTTTGCTTATGCTGCCCGTTCAGGCGCGTCAGTAGGT
ATCGATGACATGGTAATCCCTGCCAAGAAAGCAGAGATCATCGAAGAAGCAGAAACCGAAGTTGCCGAAATCCAGGAGCA
GTTCCAGTCTGGTTTGGTTACCGCCGGCGAACGCTACAACAAAGTGATCGATATCTGGGCCGCAGCGAACGAACGTGTTG
CCAAGGCAATGATGGAAAACTTGTCTGTTGAAGACGTCGTCAACCGTGACGGTGTTGTTGAACAGCAGGTTTCCTTCAAC
AGTATCTTTATGATGGCCGACTCCGGTGCGCGTGGTTCTGCAGCACAGATTCGTCAGCTGGCCGGTATGCGTGGCCTGAT
GGCCAAGCCGGATGGTTCCATCATTGAAACGCCAATCACCGCGAACTTCCGTGAAGGTCTGAACGTACTCCAGTACTTCA
TCTCCACGCACGGTGCTCGTAAAGGTTTGGCGGATACCGCACTGAAAACGGCTAACTCCGGTTATCTGACCCGTCGTCTG
GTTGACGTGGCGCAGGATCTGGTGGTTACCGAGGACGACTGTGGTACTCACAACGGCATCATGATGACTCCGGTTATCGA
AGGTGGTGACGTTAAAGAGCCACTGCGCGAACGTGTTCTGGGTCGTGTGACAGCAGAAGATATCATCAAGCCGGGTACGG
CTGATATCCTGGTGCCACGTAACACCCTGCTGCACGAGAAGACTTGTGACCTGTTGGAAGAAAACTCTGTCGACAGCGTT
AAAGTCCGTTCCGTCGTTAGCTGTGAAACCGACTTTGGTGTGTGTGCAAACTGCTATGGTCGCGACCTGGCACGTGGTCA
CATCATCAACAAAGGCGAAGCTATCGGCGTTATCGCGGCACAGTCAATCGGTGAGCCGGGTACACAGCTGACGATGCGTA
CGTTCCACATCGGTGGTGCGGCATCTCGTGCGGCTGCTGAATCCAGCATCCAGGTGAAAAACAAGGGTACTCTGAAGCTG
AGCAATGTGAAGTTCGTAATGAACGCCGCAGGCAAGCTGGTGATCACCTCTCGTAACACCGAACTGAAGCTGATCGACGA
ATTCGGCCGTACTAAAGAACGCTACAAAGTGCCTTACGGTTCCGTGATGGGCAAAGGCGACGGTATGGAAGTTAACGGCG
GCGAAACCGTTGCTAACTGGGATCCGCACACCATGCCAGTTATCACCGAAGTGAGTGGTTTCATCCGCTTCGCTGATATG
GTTGACGGCCAGACCATTACCCGCCAGACCGACGAACTGACCGGTTTGTCTTCTCTGGTAGTACTGGACAGCGCAGAGCG
TACCGGTAGCGGTAAAGACCTGCGTCCGGCACTGAAAATCGTTGATGCCAAAGGCGACGACGTATTGATCCCAGGTACTG
ATATGCCTGCTCAATACTTCCTGCCAGGTAAAGCGATTGTACAGCTGGAAGACGGCATTCAGATCGGTGCGGGTGATACC
CTGGCGCGTATTCCTCAGGAATCCGGCGGTACCAAGGATATTACCGGTGGTCTGCCACGCGTTGCGGATCTGTTCGAAGC
ACGTCGTCCGAAAGAGCCGGCAATCCTGGCTGAAATCAGCGGGATTATCTCGTTCGGTAAAGAGACCAAAGGCAAACGTC
GCCTGGTAATCTCTCCACTGGACGGCAGCGATGCGTACGAAGAGATGATTCCAAAATGGCGTCAGCTCAACGTGTTCGAA
GGTGAAGTTGTGGAACGTGGTGACGTTGTTTCTGACGGCCCAGAATCTCCACACGACATTCTGCGTCTGCGTGGTGTGCA
TGCGGTTACTCGCTACATCACCAACGAAGTGCAGGAAGTTTACCGTCTGCAAGGCGTTAAGATTAACGATAAACACATTG
AAGTTATCGTTCGTCAGATGCTGCGTAAAGGCACCATCGTTAGCGCTGGTGGCACCGAGTTCCTGGAAGGCGAGCAGGCT
GAAGTGTCTCGCGTTAAGATTGCCAACCGTCAGCTTGCTGCTGAAGGCAAAATCGAGGCAACCTTCTCACGCGATCTGCT
GGGTATCACCAAGGCTTCCTTGGCGACCGAGTCCTTCATCTCCGCAGCATCGTTCCAGGAAACGACGCGCGTTCTGACCG
AAGCGGCTGTTGCCGGTAAGCGTGATGAACTGCGTGGCCTGAAAGAGAACGTCATCGTGGGCCGTCTGATCCCAGCCGGT
ACCGGTTACGCTTATCATCAGGACCGCATGCGTCGTAAAGCACAGGGTGAAACGCCAGTTGTTCCGCAGGTGAGCGCGGA
AGAAGCAACGGCTAACCTGGCTGAACTGCTCAATGCAGGCAACCTGGGTGGCGGCAACAACGATTAA

Upstream 100 bases:

>100_bases
CTCCCGGCCTTAGGGAGCCTGAGGGTGGTTGTTCAGGTCACACGGGCGCGCGATTTGTCAGCGAGCGCCCAACAGGTTTA
ACTCCGACAGGAGCCAATCC

Downstream 100 bases:

>100_bases
TCGTTGAATGCGCCTTGGGGTTCGGCATTGCCGGGCCCTGACCAGATAAACCGCTCCTTCGGGGGCGGTTTTTTTTTGCC
TGTGAACCGGGCCGGGTGAG

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1408; Mature: 1408

Protein sequence:

>1408_residues
MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERRQIL
TEEQYLDALEEFGDEFDAKMGAEAIQALLKNMDLEQECETLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILT
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKM
VEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
RALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLSGPKEAERIYRAGLASLHARVKVRITEEIKNTE
GESVHQTSIVDTTVGRAILWMIVPRGLPYSIVNQPLGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVG
IDDMVIPAKKAEIIEEAETEVAEIQEQFQSGLVTAGERYNKVIDIWAAANERVAKAMMENLSVEDVVNRDGVVEQQVSFN
SIFMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDLVVTEDDCGTHNGIMMTPVIEGGDVKEPLRERVLGRVTAEDIIKPGTADILVPRNTLLHEKTCDLLEENSVDSV
KVRSVVSCETDFGVCANCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGTLKL
SNVKFVMNAAGKLVITSRNTELKLIDEFGRTKERYKVPYGSVMGKGDGMEVNGGETVANWDPHTMPVITEVSGFIRFADM
VDGQTITRQTDELTGLSSLVVLDSAERTGSGKDLRPALKIVDAKGDDVLIPGTDMPAQYFLPGKAIVQLEDGIQIGAGDT
LARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIISFGKETKGKRRLVISPLDGSDAYEEMIPKWRQLNVFE
GEVVERGDVVSDGPESPHDILRLRGVHAVTRYITNEVQEVYRLQGVKINDKHIEVIVRQMLRKGTIVSAGGTEFLEGEQA
EVSRVKIANRQLAAEGKIEATFSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAG
TGYAYHQDRMRRKAQGETPVVPQVSAEEATANLAELLNAGNLGGGNND

Sequences:

>Translated_1408_residues
MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERRQIL
TEEQYLDALEEFGDEFDAKMGAEAIQALLKNMDLEQECETLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILT
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKM
VEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
RALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLSGPKEAERIYRAGLASLHARVKVRITEEIKNTE
GESVHQTSIVDTTVGRAILWMIVPRGLPYSIVNQPLGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVG
IDDMVIPAKKAEIIEEAETEVAEIQEQFQSGLVTAGERYNKVIDIWAAANERVAKAMMENLSVEDVVNRDGVVEQQVSFN
SIFMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDLVVTEDDCGTHNGIMMTPVIEGGDVKEPLRERVLGRVTAEDIIKPGTADILVPRNTLLHEKTCDLLEENSVDSV
KVRSVVSCETDFGVCANCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGTLKL
SNVKFVMNAAGKLVITSRNTELKLIDEFGRTKERYKVPYGSVMGKGDGMEVNGGETVANWDPHTMPVITEVSGFIRFADM
VDGQTITRQTDELTGLSSLVVLDSAERTGSGKDLRPALKIVDAKGDDVLIPGTDMPAQYFLPGKAIVQLEDGIQIGAGDT
LARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIISFGKETKGKRRLVISPLDGSDAYEEMIPKWRQLNVFE
GEVVERGDVVSDGPESPHDILRLRGVHAVTRYITNEVQEVYRLQGVKINDKHIEVIVRQMLRKGTIVSAGGTEFLEGEQA
EVSRVKIANRQLAAEGKIEATFSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAG
TGYAYHQDRMRRKAQGETPVVPQVSAEEATANLAELLNAGNLGGGNND
>Mature_1408_residues
MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERRQIL
TEEQYLDALEEFGDEFDAKMGAEAIQALLKNMDLEQECETLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILT
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKM
VEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
RALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLSGPKEAERIYRAGLASLHARVKVRITEEIKNTE
GESVHQTSIVDTTVGRAILWMIVPRGLPYSIVNQPLGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVG
IDDMVIPAKKAEIIEEAETEVAEIQEQFQSGLVTAGERYNKVIDIWAAANERVAKAMMENLSVEDVVNRDGVVEQQVSFN
SIFMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDLVVTEDDCGTHNGIMMTPVIEGGDVKEPLRERVLGRVTAEDIIKPGTADILVPRNTLLHEKTCDLLEENSVDSV
KVRSVVSCETDFGVCANCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGTLKL
SNVKFVMNAAGKLVITSRNTELKLIDEFGRTKERYKVPYGSVMGKGDGMEVNGGETVANWDPHTMPVITEVSGFIRFADM
VDGQTITRQTDELTGLSSLVVLDSAERTGSGKDLRPALKIVDAKGDDVLIPGTDMPAQYFLPGKAIVQLEDGIQIGAGDT
LARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIISFGKETKGKRRLVISPLDGSDAYEEMIPKWRQLNVFE
GEVVERGDVVSDGPESPHDILRLRGVHAVTRYITNEVQEVYRLQGVKINDKHIEVIVRQMLRKGTIVSAGGTEFLEGEQA
EVSRVKIANRQLAAEGKIEATFSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAG
TGYAYHQDRMRRKAQGETPVVPQVSAEEATANLAELLNAGNLGGGNND

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=922, Percent_Identity=25.8134490238612, Blast_Score=204, Evalue=7e-52,
Organism=Homo sapiens, GI103471997, Length=605, Percent_Identity=26.2809917355372, Blast_Score=137, Evalue=8e-32,
Organism=Homo sapiens, GI39725938, Length=308, Percent_Identity=31.4935064935065, Blast_Score=136, Evalue=1e-31,
Organism=Escherichia coli, GI2367335, Length=1408, Percent_Identity=92.8977272727273, Blast_Score=2681, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=911, Percent_Identity=24.9176728869374, Blast_Score=182, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI25145495, Length=318, Percent_Identity=31.7610062893082, Blast_Score=149, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6324690, Length=373, Percent_Identity=31.0991957104558, Blast_Score=144, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320061, Length=314, Percent_Identity=32.1656050955414, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI17530899, Length=846, Percent_Identity=25.0591016548463, Blast_Score=184, Evalue=4e-46,
Organism=Drosophila melanogaster, GI281360912, Length=324, Percent_Identity=29.6296296296296, Blast_Score=134, Evalue=5e-31,
Organism=Drosophila melanogaster, GI17647875, Length=329, Percent_Identity=28.5714285714286, Blast_Score=101, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_SERP5 (A8G8E8)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001476516.1
- ProteinModelPortal:   A8G8E8
- STRING:   A8G8E8
- GeneID:   5607012
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0278
- eggNOG:   COG0086
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- ProtClustDB:   PRK00566
- BioCyc:   SPRO399741:SPRO_0278-MONOMER
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 155226; Mature: 155226

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCAR
CHHHHHHHHHHCCCCCCCEEEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEECCCCEEEHHHHHH
PSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERRQILTEEQYLDALEEFGDEFDAKM
HHHHCEEECCCHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAEAIQALLKNMDLEQECETLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILT
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQ
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHHH
EAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPY
HHHHHHHCCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCC
LRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHP
HHHHHCCCCHHHHHHHHHHHHHCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
EEECCCCCHHHHCHHHCCCEEECCCEEEEECEEEEEECCCCCCCCEEEEEEEEEECCHHH
RALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLSGPKEAERIYRAG
HHHEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHH
LASLHARVKVRITEEIKNTEGESVHQTSIVDTTVGRAILWMIVPRGLPYSIVNQPLGKKA
HHHHHHEEEEEEHHHHCCCCCCCEEHHHHHHHHHHHHHEEHHHCCCCCHHHHCCCCCHHH
ISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPAKKAEIIEEAETE
HHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHHH
VAEIQEQFQSGLVTAGERYNKVIDIWAAANERVAKAMMENLSVEDVVNRDGVVEQQVSFN
HHHHHHHHHCCCCCCCHHHHHEEEEEHHCHHHHHHHHHHCCCHHHHHCCCCCCHHHCCCC
SIFMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
KGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHNGIMMTPVIEGGDVKEPLRERVL
CCHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHH
GRVTAEDIIKPGTADILVPRNTLLHEKTCDLLEENSVDSVKVRSVVSCETDFGVCANCYG
HHCCHHHHCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCEEHHHEEECCCCCCHHHHHHC
RDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGTLKL
CHHHCCCEECCCCEEEEEEECCCCCCCCEEEEEEEECCCCHHHHHCCCCEEECCCCCEEE
SNVKFVMNAAGKLVITSRNTELKLIDEFGRTKERYKVPYGSVMGKGDGMEVNGGETVANW
ECEEEEECCCCEEEEEECCCCEEEHHHHCCCHHHEECCCHHHCCCCCCEEECCCCEECCC
DPHTMPVITEVSGFIRFADMVDGQTITRQTDELTGLSSLVVLDSAERTGSGKDLRPALKI
CCCCCHHHHHHHHHHHHHHHHCCCHHHCCHHHHCCCCCEEEEECCCCCCCCCCCCCHHEE
VDAKGDDVLIPGTDMPAQYFLPGKAIVQLEDGIQIGAGDTLARIPQESGGTKDITGGLPR
EECCCCEEEECCCCCCCEEECCCCEEEEEECCEEECCCCHHHHCCCCCCCCCCCCCCCHH
VADLFEARRPKEPAILAEISGIISFGKETKGKRRLVISPLDGSDAYEEMIPKWRQLNVFE
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHCCHHHCCCCCC
GEVVERGDVVSDGPESPHDILRLRGVHAVTRYITNEVQEVYRLQGVKINDKHIEVIVRQM
CCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHH
LRKGTIVSAGGTEFLEGEQAEVSRVKIANRQLAAEGKIEATFSRDLLGITKASLATESFI
HHCCCEEECCCCHHHCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHH
SAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRKAQGETPV
HHHHHHHHHHHHHHHHHCCCHHHHHCHHHCCEEEEEECCCCCCHHHHHHHHHHHCCCCCC
VPQVSAEEATANLAELLNAGNLGGGNND
CCCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCAR
CHHHHHHHHHHCCCCCCCEEEEEECCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEECCCCEEEHHHHHH
PSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERRQILTEEQYLDALEEFGDEFDAKM
HHHHCEEECCCHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAEAIQALLKNMDLEQECETLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILT
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQ
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHHH
EAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPY
HHHHHHHCCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCC
LRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHP
HHHHHCCCCHHHHHHHHHHHHHCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
EEECCCCCHHHHCHHHCCCEEECCCEEEEECEEEEEECCCCCCCCEEEEEEEEEECCHHH
RALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLSGPKEAERIYRAG
HHHEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHH
LASLHARVKVRITEEIKNTEGESVHQTSIVDTTVGRAILWMIVPRGLPYSIVNQPLGKKA
HHHHHHEEEEEEHHHHCCCCCCCEEHHHHHHHHHHHHHEEHHHCCCCCHHHHCCCCCHHH
ISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPAKKAEIIEEAETE
HHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHHH
VAEIQEQFQSGLVTAGERYNKVIDIWAAANERVAKAMMENLSVEDVVNRDGVVEQQVSFN
HHHHHHHHHCCCCCCCHHHHHEEEEEHHCHHHHHHHHHHCCCHHHHHCCCCCCHHHCCCC
SIFMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
KGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHNGIMMTPVIEGGDVKEPLRERVL
CCHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCEEEEEEECCCCCHHHHHHHHH
GRVTAEDIIKPGTADILVPRNTLLHEKTCDLLEENSVDSVKVRSVVSCETDFGVCANCYG
HHCCHHHHCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCEEHHHEEECCCCCCHHHHHHC
RDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGTLKL
CHHHCCCEECCCCEEEEEEECCCCCCCCEEEEEEEECCCCHHHHHCCCCEEECCCCCEEE
SNVKFVMNAAGKLVITSRNTELKLIDEFGRTKERYKVPYGSVMGKGDGMEVNGGETVANW
ECEEEEECCCCEEEEEECCCCEEEHHHHCCCHHHEECCCHHHCCCCCCEEECCCCEECCC
DPHTMPVITEVSGFIRFADMVDGQTITRQTDELTGLSSLVVLDSAERTGSGKDLRPALKI
CCCCCHHHHHHHHHHHHHHHHCCCHHHCCHHHHCCCCCEEEEECCCCCCCCCCCCCHHEE
VDAKGDDVLIPGTDMPAQYFLPGKAIVQLEDGIQIGAGDTLARIPQESGGTKDITGGLPR
EECCCCEEEECCCCCCCEEECCCCEEEEEECCEEECCCCHHHHCCCCCCCCCCCCCCCHH
VADLFEARRPKEPAILAEISGIISFGKETKGKRRLVISPLDGSDAYEEMIPKWRQLNVFE
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHCCHHHCCCCCC
GEVVERGDVVSDGPESPHDILRLRGVHAVTRYITNEVQEVYRLQGVKINDKHIEVIVRQM
CCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHH
LRKGTIVSAGGTEFLEGEQAEVSRVKIANRQLAAEGKIEATFSRDLLGITKASLATESFI
HHCCCEEECCCCHHHCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHH
SAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRKAQGETPV
HHHHHHHHHHHHHHHHHCCCHHHHHCHHHCCEEEEEECCCCCCHHHHHHHHHHHCCCCCC
VPQVSAEEATANLAELLNAGNLGGGNND
CCCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA