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The map label for this gene is cobU [H]

Identifier: 157156453

GI number: 157156453

Start: 2243046

End: 2243591

Strand: Reverse

Name: cobU [H]

Synonym: EcE24377A_2275

Alternate gene names: 157156453

Gene position: 2243591-2243046 (Counterclockwise)

Preceding gene: 157156911

Following gene: 157157942

Centisome position: 45.06

GC content: 50.92

Gene sequence:

>546_bases
ATGATGATTTTGGTGACGGGGGGCGCACGGAGCGGGAAGAGTCGCCATGCAGAGGCGCTTATTGGGGACTCTTCACAGGT
TCTGTATATCGCCACCTCACAAATCCTTGATGATGAGATGGCTGCACGGATAGAACATCATCGGCAAGGCCGCCCGGCGC
ACTGGCGCACGGTGGAGCGTTGGCAACATCTTGATGAATTAATTCATGCAGACATTAACCCGCATGAGGCTGTATTGCTG
GAATGCGTTACCACCATGGTGACTAATCTGTTGTTTGATTATGGCGGCGATAAAGACCCTGATGAATGGGATTATCAGGC
GATGGAACAGGCGATTAATGCTGAGATTCAGTCGTTGATTGCTGCCTGCCAACGTTGTCCCGCAAAGGTTGTATTAGTGA
CTAACGAAGTGGGAATGGGGATTGTGCCGGAGAGTCGTCTGGCACGACATTTTCGTGATATTGCCGGGCGGGTAAATCAG
CAGCTGGCCGCTGCGGCAAATGAAGTATGGTTGGTGGTTTCGGGTATTGGAGTAAAAATCAAATGA

Upstream 100 bases:

>100_bases
CGCGCAGTATTAATCGCGTAAATGTTTTGCGGTCAGCAACGGTGGGGGATCCATTGTTCTGTTCAATGAATACCATCATA
CAATTGAATCAGGAGTCGGT

Downstream 100 bases:

>100_bases
GTAAATTATTTTGGGCGATGCTCTCTTTTATTACGCGTCTGCCTGTACCGCGTCGCTGGTCCCAGGGACTGGATTTCGAG
CATTATTCTCGCGGTATTAT

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MMILVTGGARSGKSRHAEALIGDSSQVLYIATSQILDDEMAARIEHHRQGRPAHWRTVERWQHLDELIHADINPHEAVLL
ECVTTMVTNLLFDYGGDKDPDEWDYQAMEQAINAEIQSLIAACQRCPAKVVLVTNEVGMGIVPESRLARHFRDIAGRVNQ
QLAAAANEVWLVVSGIGVKIK

Sequences:

>Translated_181_residues
MMILVTGGARSGKSRHAEALIGDSSQVLYIATSQILDDEMAARIEHHRQGRPAHWRTVERWQHLDELIHADINPHEAVLL
ECVTTMVTNLLFDYGGDKDPDEWDYQAMEQAINAEIQSLIAACQRCPAKVVLVTNEVGMGIVPESRLARHFRDIAGRVNQ
QLAAAANEVWLVVSGIGVKIK
>Mature_181_residues
MMILVTGGARSGKSRHAEALIGDSSQVLYIATSQILDDEMAARIEHHRQGRPAHWRTVERWQHLDELIHADINPHEAVLL
ECVTTMVTNLLFDYGGDKDPDEWDYQAMEQAINAEIQSLIAACQRCPAKVVLVTNEVGMGIVPESRLARHFRDIAGRVNQ
QLAAAANEVWLVVSGIGVKIK

Specific function: ATP-dependent phosphorylation of adenosylcobinamide and adds GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=181, Percent_Identity=98.3425414364641, Blast_Score=367, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 20101; Mature: 20101

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMILVTGGARSGKSRHAEALIGDSSQVLYIATSQILDDEMAARIEHHRQGRPAHWRTVER
CEEEEECCCCCCCCHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
WQHLDELIHADINPHEAVLLECVTTMVTNLLFDYGGDKDPDEWDYQAMEQAINAEIQSLI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
AACQRCPAKVVLVTNEVGMGIVPESRLARHFRDIAGRVNQQLAAAANEVWLVVSGIGVKI
HHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEE
K
C
>Mature Secondary Structure
MMILVTGGARSGKSRHAEALIGDSSQVLYIATSQILDDEMAARIEHHRQGRPAHWRTVER
CEEEEECCCCCCCCHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
WQHLDELIHADINPHEAVLLECVTTMVTNLLFDYGGDKDPDEWDYQAMEQAINAEIQSLI
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
AACQRCPAKVVLVTNEVGMGIVPESRLARHFRDIAGRVNQQLAAAANEVWLVVSGIGVKI
HHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEE
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]