Click here to switch to the map view.

The map label for this gene is yedQ [H]

Identifier: 157155861

GI number: 157155861

Start: 2155907

End: 2157583

Strand: Reverse

Name: yedQ [H]

Synonym: EcE24377A_2187

Alternate gene names: 157155861

Gene position: 2157583-2155907 (Counterclockwise)

Preceding gene: 157155225

Following gene: 157156352

Centisome position: 43.33

GC content: 51.28

Gene sequence:

>1677_bases
ATGGAAAACCAGAGCTGGTTGAAAAAACTCGCACGCCGCCTGGGGCCTGGTCATGTCGTTAATCTCTGCTTTATCGTGGT
ATTGCTTTTTTCCACCTTGCTCACCTGGCGTGAAGTAGTGGTGCTGGAAGATGCCTATATCTCCAGCCAGCGTAATCATC
TGGAAAACGTAGCCAACGCGCTCGATAAGCATTTGCAGTATAACGTCGACAAACTGATCTTTTTGCGTAATGGCATGCGC
GAAGCTCTCGTAGCGCCACTGGATTTCACTTCACTGCGTAATGCTGTAACCGAGTTCGAACAGCATCGCGACGAGCACGC
CTGGCAAATTGAACTCAACCGACGGCGCACTCTGCCAGTTAATGGTGTGTCGGATGCATTAGTCAGCGAGGGGAATCTCC
TGTCTCGCGAAAATGAAAGCCTCGACAATGAAATTACCGCTGCACTGGAAGTTGGTTACTTGCTGCGACTGGCGCACAAC
TCCTCGTCGATGGTTGAACAGGCGATGTATGTCTCGCGTGCCGGATTTTACGTTTCGACGCAGCCGACCTTGTTTACGCG
CAATGTTCCAACGCGTTATTACGGCTATGTCACCCAACCCTGGTTTATCGGCCATTCGCAACGAGAAAATCGTCACCGCG
CGGTACGCTGGTTTACTTCGCAACCGGAACACGCCAGCAATACTGAACCGCAGGTTACCGTCAGTGTTCCGGTAGACAGT
AATAACTACTGGTATGGCGTGCTGGGGATGAGTATTCCTGTGCGTACTATGCAGCAATTTTTAAGAAACGCCATCGATAA
AAACCTCGATGGTGAGTATCAGCTCTATGACAGTAAGCTGAGATTTTTGACCTCTTCCAATCCTGACCATCCAACAGGGA
ATATTTTTGATCCTCGTGAACTGGCCTTGCTGGCGCAGGCGATGGAACATGACACGCGGGGCGGCATTCGTATGGACAGT
CGCTATGTTAGCTGGGAACGTCTGGACCATTTCGACGGTGTGCTGGTGCGCGTCCATACGCTAAGCGAAGGCGTGCGCGG
CGATTTCGGTAGTATCAGCATTGCATTAACCCTGCTGTGGGCGCTCTTTACCACCATGTTACTCATCTCCTGGTATGTGA
TTCGCCGGATGGTTAGCAACATGTATGTTCTGCAAAGCTCGTTGCAGTGGCAGGCGTGGCACGACACCTTAACCCGTTTA
TATAATAGTGGCGCACTGTTTGAAAAAGCCCGTCCGCTCGCGAAATTGTGTCAGACGCACCAACATCCTTTTTCTGTCAT
TCAGGTCGATCTTGACCATTTTAAAGCGATTAATGACCGCTTTGGTCATCAGGCGGGCGACCGTGTTCTTTCTCATGCTG
CCGGATTAATTAGCAGTTCCTTGCGTGCGCAGGACGTTGCCGGGCGGGTCGGTGGTGAGGAGTTTTGTGTGATTCTGCCA
GGCGCGAGTCTGACGGAGGCTGCGGAAGTCGCAGAACGTATTCGCCTGAAGTTAAATGAAAAAGAGATGCTGATTGCTAA
GAGTACGACGATACGCATCAGTGCCTCGTTGGGGGTTAGTAGCAGCGAGGAAACCGGTGATTATGATTTTGAACAACTCC
AGTCACTGGCTGACCGTCGGCTTTATCTCGCTAAACAGGCCGGGCGTAATCTGGTATGCGCGAGCGATAACGCTTAA

Upstream 100 bases:

>100_bases
ATTATAAAATTATCGCTGTTTTGCGGTACGCTATCGCCAGGTTATGCCAGAATCATAAAAAAGCAGGTTGGGAGTCGTCA
GGGTGCAGCACGAGACAAAA

Downstream 100 bases:

>100_bases
CGAGCGGAGAAAAAATGGTCCAGCCCTTCACGCCAGCCTTCCGGTCCTTCACGCTGCGTTCGCCAGACGCGGGTCGGATC
CTCATCATGCAGATGCACCC

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 558

Protein sequence:

>558_residues
MENQSWLKKLARRLGPGHVVNLCFIVVLLFSTLLTWREVVVLEDAYISSQRNHLENVANALDKHLQYNVDKLIFLRNGMR
EALVAPLDFTSLRNAVTEFEQHRDEHAWQIELNRRRTLPVNGVSDALVSEGNLLSRENESLDNEITAALEVGYLLRLAHN
SSSMVEQAMYVSRAGFYVSTQPTLFTRNVPTRYYGYVTQPWFIGHSQRENRHRAVRWFTSQPEHASNTEPQVTVSVPVDS
NNYWYGVLGMSIPVRTMQQFLRNAIDKNLDGEYQLYDSKLRFLTSSNPDHPTGNIFDPRELALLAQAMEHDTRGGIRMDS
RYVSWERLDHFDGVLVRVHTLSEGVRGDFGSISIALTLLWALFTTMLLISWYVIRRMVSNMYVLQSSLQWQAWHDTLTRL
YNSGALFEKARPLAKLCQTHQHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILP
GASLTEAAEVAERIRLKLNEKEMLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRRLYLAKQAGRNLVCASDNA

Sequences:

>Translated_558_residues
MENQSWLKKLARRLGPGHVVNLCFIVVLLFSTLLTWREVVVLEDAYISSQRNHLENVANALDKHLQYNVDKLIFLRNGMR
EALVAPLDFTSLRNAVTEFEQHRDEHAWQIELNRRRTLPVNGVSDALVSEGNLLSRENESLDNEITAALEVGYLLRLAHN
SSSMVEQAMYVSRAGFYVSTQPTLFTRNVPTRYYGYVTQPWFIGHSQRENRHRAVRWFTSQPEHASNTEPQVTVSVPVDS
NNYWYGVLGMSIPVRTMQQFLRNAIDKNLDGEYQLYDSKLRFLTSSNPDHPTGNIFDPRELALLAQAMEHDTRGGIRMDS
RYVSWERLDHFDGVLVRVHTLSEGVRGDFGSISIALTLLWALFTTMLLISWYVIRRMVSNMYVLQSSLQWQAWHDTLTRL
YNSGALFEKARPLAKLCQTHQHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILP
GASLTEAAEVAERIRLKLNEKEMLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRRLYLAKQAGRNLVCASDNA
>Mature_558_residues
MENQSWLKKLARRLGPGHVVNLCFIVVLLFSTLLTWREVVVLEDAYISSQRNHLENVANALDKHLQYNVDKLIFLRNGMR
EALVAPLDFTSLRNAVTEFEQHRDEHAWQIELNRRRTLPVNGVSDALVSEGNLLSRENESLDNEITAALEVGYLLRLAHN
SSSMVEQAMYVSRAGFYVSTQPTLFTRNVPTRYYGYVTQPWFIGHSQRENRHRAVRWFTSQPEHASNTEPQVTVSVPVDS
NNYWYGVLGMSIPVRTMQQFLRNAIDKNLDGEYQLYDSKLRFLTSSNPDHPTGNIFDPRELALLAQAMEHDTRGGIRMDS
RYVSWERLDHFDGVLVRVHTLSEGVRGDFGSISIALTLLWALFTTMLLISWYVIRRMVSNMYVLQSSLQWQAWHDTLTRL
YNSGALFEKARPLAKLCQTHQHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILP
GASLTEAAEVAERIRLKLNEKEMLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRRLYLAKQAGRNLVCASDNA

Specific function: Involves in the regulation of cellulose production [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87082007, Length=558, Percent_Identity=99.1039426523297, Blast_Score=1142, Evalue=0.0,
Organism=Escherichia coli, GI1787262, Length=246, Percent_Identity=30.4878048780488, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI145693134, Length=187, Percent_Identity=34.2245989304813, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788381, Length=165, Percent_Identity=33.9393939393939, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87081881, Length=172, Percent_Identity=34.3023255813954, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787802, Length=170, Percent_Identity=36.4705882352941, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786584, Length=163, Percent_Identity=34.9693251533742, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI87081974, Length=215, Percent_Identity=29.7674418604651, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081977, Length=164, Percent_Identity=32.3170731707317, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788085, Length=190, Percent_Identity=30.5263157894737, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787056, Length=121, Percent_Identity=37.1900826446281, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787541, Length=130, Percent_Identity=36.9230769230769, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787816, Length=124, Percent_Identity=36.2903225806452, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160 [H]

Pfam domain/function: PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 63372; Mature: 63372

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENQSWLKKLARRLGPGHVVNLCFIVVLLFSTLLTWREVVVLEDAYISSQRNHLENVANA
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHH
LDKHLQYNVDKLIFLRNGMREALVAPLDFTSLRNAVTEFEQHRDEHAWQIELNRRRTLPV
HHHHHHCCHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
NGVSDALVSEGNLLSRENESLDNEITAALEVGYLLRLAHNSSSMVEQAMYVSRAGFYVST
CCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEC
QPTLFTRNVPTRYYGYVTQPWFIGHSQRENRHRAVRWFTSQPEHASNTEPQVTVSVPVDS
CCEEEECCCCCHHEEEECCCEEECCCCCCCCHHHEEEECCCCCCCCCCCCEEEEEEEECC
NNYWYGVLGMSIPVRTMQQFLRNAIDKNLDGEYQLYDSKLRFLTSSNPDHPTGNIFDPRE
CCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHEECCCCCCCCCCCCCHHH
LALLAQAMEHDTRGGIRMDSRYVSWERLDHFDGVLVRVHTLSEGVRGDFGSISIALTLLW
HHHHHHHHHHCCCCCEEECCCCCCHHHHHCCCCEEEEEEEHHCCCCCCCCHHHHHHHHHH
ALFTTMLLISWYVIRRMVSNMYVLQSSLQWQAWHDTLTRLYNSGALFEKARPLAKLCQTH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHCCHHHHHHHCC
QHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILP
CCCCEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
GASLTEAAEVAERIRLKLNEKEMLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRR
CCCHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHH
LYLAKQAGRNLVCASDNA
HHHHHHHCCEEEECCCCC
>Mature Secondary Structure
MENQSWLKKLARRLGPGHVVNLCFIVVLLFSTLLTWREVVVLEDAYISSQRNHLENVANA
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHH
LDKHLQYNVDKLIFLRNGMREALVAPLDFTSLRNAVTEFEQHRDEHAWQIELNRRRTLPV
HHHHHHCCHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
NGVSDALVSEGNLLSRENESLDNEITAALEVGYLLRLAHNSSSMVEQAMYVSRAGFYVST
CCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEC
QPTLFTRNVPTRYYGYVTQPWFIGHSQRENRHRAVRWFTSQPEHASNTEPQVTVSVPVDS
CCEEEECCCCCHHEEEECCCEEECCCCCCCCHHHEEEECCCCCCCCCCCCEEEEEEEECC
NNYWYGVLGMSIPVRTMQQFLRNAIDKNLDGEYQLYDSKLRFLTSSNPDHPTGNIFDPRE
CCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHEECCCCCCCCCCCCCHHH
LALLAQAMEHDTRGGIRMDSRYVSWERLDHFDGVLVRVHTLSEGVRGDFGSISIALTLLW
HHHHHHHHHHCCCCCEEECCCCCCHHHHHCCCCEEEEEEEHHCCCCCCCCHHHHHHHHHH
ALFTTMLLISWYVIRRMVSNMYVLQSSLQWQAWHDTLTRLYNSGALFEKARPLAKLCQTH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHCCHHHHHHHCC
QHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILP
CCCCEEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
GASLTEAAEVAERIRLKLNEKEMLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRR
CCCHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHH
LYLAKQAGRNLVCASDNA
HHHHHHHCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]