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The map label for this gene is yjjN

Identifier: 157163806

GI number: 157163806

Start: 4599302

End: 4600324

Strand: Direct

Name: yjjN

Synonym: EcHS_A4590

Alternate gene names: 157163806

Gene position: 4599302-4600324 (Clockwise)

Preceding gene: 157163805

Following gene: 157163814

Centisome position: 99.05

GC content: 51.03

Gene sequence:

>1023_bases
ATGTCTACGATGAATGTTTTAATTTGCCAGCAGCCGAAAGAATTAGTCTGGAAACAACGCGAGATACCTATTCCGGGTGA
CAATGAAGCATTAATAAAAATTAAGTCTGTCGGGATTTGCGGTACCGATATTCATGCCTGGGGTGGAAATCAACCATTTT
TTAGTTATCCACGTGTTTTAGGCCATGAAATATGTGGGGAGATTGTTGGGCTGGGTAAAAATATTGCTGATCTTAAAAAT
GGTCAGCAAGTTGCTGTGATCCCTTATGTTGCCTGTCAGCAATGCCCGGCGTGTAAAAGCGGGCGTACCAATTGCTGTGA
AAAAATTTCAGTCATTGGCGTGCATCAGGATGGCGGTTTTAGTGAGTATTTGAGCGTGCCGGTGGCGAACATTTTGCCCG
CAGACGGTATTGACCCGCAGGCGGCCGCATTGATTGAACCTTTCGCTATTAGCGCTCATGCGGTGCGTCGCGCAGCCATT
GCTCCCGGCGAGCAGGTGCTGGTGGTCGGGGCGGGGCCAATCGGTTTGGGCGCGGCGGCAATCGCTAAAGCCGATGGCGC
ACAGGTGGTGGTGGCGGATACCAGTCCGGCGCGCCGTGAACATGTGGCAACGCGTCTGGAATTACCTTTACTGGACCCGT
CAGCCGAAGATTTTGACGCGCAGCTACGGGCGCAGTTTGGTGGTTCGCTGGCGCAGAAAGTGATCGACGCGACAGGTAAT
CAACATGCGATGAATAACACCGTGAATTTGATTCGTCACGGCGGCACGGTGGTATTTGTCGGCCTGTTTAAAGGTGAGTT
GCAGTTCTCCGATCCGGAATTCCATAAAAAAGAAACGACGATGATGGGCAGCCGCAACGCCACGCCGGAAGATTTTGCTA
AAGTCGGTCGACTGATGGCGGAAGGAAAAATCACTGCCGACATGATGTTAACCCATCGCTATCCGTTCGCCACGCTGGCA
GAAACCTACGAGCGCGATGTGATTAACAATCGTGAGTTGATTAAGGGTGTAATTACTTTCTGA

Upstream 100 bases:

>100_bases
ACATTTTTATGCGTGTGTTTTCACAAAACAGATTTTCCGTTCCGCTGCCATTTTTCATTTTCATTGATATCTAAGGCAAC
AAAAAATGGAGAGCCGAATC

Downstream 100 bases:

>100_bases
TAAGGCGAGATTATTAAAGTTGCCATGCAGCGTCCGGGGAAGTGTTGGGCGCTGTTTTTTTTCTGTTTCTCAATGATGTT
TTGTAGGCCGGAGAAGATGT

Product: zinc-binding dehydrogenase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSTMNVLICQQPKELVWKQREIPIPGDNEALIKIKSVGICGTDIHAWGGNQPFFSYPRVLGHEICGEIVGLGKNIADLKN
GQQVAVIPYVACQQCPACKSGRTNCCEKISVIGVHQDGGFSEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAI
APGEQVLVVGAGPIGLGAAAIAKADGAQVVVADTSPARREHVATRLELPLLDPSAEDFDAQLRAQFGGSLAQKVIDATGN
QHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHKKETTMMGSRNATPEDFAKVGRLMAEGKITADMMLTHRYPFATLA
ETYERDVINNRELIKGVITF

Sequences:

>Translated_340_residues
MSTMNVLICQQPKELVWKQREIPIPGDNEALIKIKSVGICGTDIHAWGGNQPFFSYPRVLGHEICGEIVGLGKNIADLKN
GQQVAVIPYVACQQCPACKSGRTNCCEKISVIGVHQDGGFSEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAI
APGEQVLVVGAGPIGLGAAAIAKADGAQVVVADTSPARREHVATRLELPLLDPSAEDFDAQLRAQFGGSLAQKVIDATGN
QHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHKKETTMMGSRNATPEDFAKVGRLMAEGKITADMMLTHRYPFATLA
ETYERDVINNRELIKGVITF
>Mature_339_residues
STMNVLICQQPKELVWKQREIPIPGDNEALIKIKSVGICGTDIHAWGGNQPFFSYPRVLGHEICGEIVGLGKNIADLKNG
QQVAVIPYVACQQCPACKSGRTNCCEKISVIGVHQDGGFSEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAIA
PGEQVLVVGAGPIGLGAAAIAKADGAQVVVADTSPARREHVATRLELPLLDPSAEDFDAQLRAQFGGSLAQKVIDATGNQ
HAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHKKETTMMGSRNATPEDFAKVGRLMAEGKITADMMLTHRYPFATLAE
TYERDVINNRELIKGVITF

Specific function: Putative L-galactonate oxidoreductase that is required for growth on L-galactonate as the sole carbon source

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family

Homologues:

Organism=Homo sapiens, GI156627571, Length=335, Percent_Identity=31.9402985074627, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI262073058, Length=373, Percent_Identity=24.1286863270777, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI71743840, Length=373, Percent_Identity=24.1286863270777, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI4501929, Length=372, Percent_Identity=25.2688172043011, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI34577061, Length=360, Percent_Identity=25.2777777777778, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI71565154, Length=203, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI156523966, Length=374, Percent_Identity=23.2620320855615, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI4501939, Length=374, Percent_Identity=23.2620320855615, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI4501933, Length=368, Percent_Identity=24.1847826086957, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI226510992, Length=340, Percent_Identity=100, Blast_Score=701, Evalue=0.0,
Organism=Escherichia coli, GI1787863, Length=343, Percent_Identity=31.7784256559767, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1790045, Length=330, Percent_Identity=29.6969696969697, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788073, Length=343, Percent_Identity=29.1545189504373, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1788407, Length=318, Percent_Identity=29.874213836478, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1788075, Length=347, Percent_Identity=27.6657060518732, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1790718, Length=305, Percent_Identity=29.1803278688525, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI87082125, Length=324, Percent_Identity=27.4691358024691, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1786825, Length=385, Percent_Identity=26.7532467532467, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI87081918, Length=312, Percent_Identity=28.8461538461538, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1786518, Length=257, Percent_Identity=28.4046692607004, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082401, Length=285, Percent_Identity=25.6140350877193, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1786552, Length=216, Percent_Identity=29.1666666666667, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=325, Percent_Identity=29.8461538461538, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17562878, Length=336, Percent_Identity=28.8690476190476, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71988145, Length=328, Percent_Identity=27.7439024390244, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562584, Length=275, Percent_Identity=29.8181818181818, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17562582, Length=324, Percent_Identity=27.7777777777778, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25146526, Length=352, Percent_Identity=24.7159090909091, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71997431, Length=354, Percent_Identity=24.5762711864407, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17565904, Length=347, Percent_Identity=24.207492795389, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6322619, Length=346, Percent_Identity=28.0346820809249, Blast_Score=139, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6319955, Length=346, Percent_Identity=27.7456647398844, Blast_Score=136, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6323099, Length=354, Percent_Identity=29.0960451977401, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6319257, Length=358, Percent_Identity=29.0502793296089, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6323961, Length=341, Percent_Identity=29.0322580645161, Blast_Score=105, Evalue=8e-24,
Organism=Saccharomyces cerevisiae, GI6324486, Length=333, Percent_Identity=30.03003003003, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319621, Length=342, Percent_Identity=28.6549707602339, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6319258, Length=327, Percent_Identity=26.2996941896024, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6323729, Length=345, Percent_Identity=27.2463768115942, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320033, Length=361, Percent_Identity=23.8227146814404, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323980, Length=185, Percent_Identity=33.5135135135135, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319949, Length=262, Percent_Identity=27.8625954198473, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17737897, Length=323, Percent_Identity=33.1269349845201, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI17137530, Length=323, Percent_Identity=31.8885448916409, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17737895, Length=374, Percent_Identity=24.8663101604278, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI45550770, Length=320, Percent_Identity=26.875, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI45551930, Length=320, Percent_Identity=26.875, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI221457811, Length=320, Percent_Identity=26.875, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YJJN_ECOLI (P39400)

Other databases:

- EMBL:   U14003
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   S56585
- RefSeq:   AP_004847.1
- RefSeq:   NP_418778.4
- ProteinModelPortal:   P39400
- SMR:   P39400
- STRING:   P39400
- EnsemblBacteria:   EBESCT00000004995
- EnsemblBacteria:   EBESCT00000016729
- GeneID:   948883
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5793
- KEGG:   eco:b4358
- EchoBASE:   EB2475
- EcoGene:   EG12590
- eggNOG:   COG1063
- GeneTree:   EBGT00050000008795
- HOGENOM:   HBG753318
- ProtClustDB:   CLSK880912
- BioCyc:   EcoCyc:G7945-MONOMER
- Genevestigator:   P39400
- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR11695

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 36448; Mature: 36317

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTMNVLICQQPKELVWKQREIPIPGDNEALIKIKSVGICGTDIHAWGGNQPFFSYPRVL
CCCCEEEEECCCHHHHHHCCCCCCCCCCCEEEEEEECCEECCCEECCCCCCCCHHHHHHH
GHEICGEIVGLGKNIADLKNGQQVAVIPYVACQQCPACKSGRTNCCEKISVIGVHQDGGF
HHHHHHHHHHCCCCHHHHCCCCEEEEEEHHHHCCCCCCCCCCCHHHHEEEEEEEECCCCH
SEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAIAPGEQVLVVGAGPIGLGAAA
HHHHHCCHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHH
IAKADGAQVVVADTSPARREHVATRLELPLLDPSAEDFDAQLRAQFGGSLAQKVIDATGN
HHCCCCCEEEEECCCCHHHHHHHHHEECCCCCCCCCCHHHHHHHHHCHHHHHHHHHCCCC
QHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHKKETTMMGSRNATPEDFAKVGRLMA
CHHHHHHHHHHCCCCEEEEEEEEECEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
EGKITADMMLTHRYPFATLAETYERDVINNRELIKGVITF
CCCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure 
STMNVLICQQPKELVWKQREIPIPGDNEALIKIKSVGICGTDIHAWGGNQPFFSYPRVL
CCCEEEEECCCHHHHHHCCCCCCCCCCCEEEEEEECCEECCCEECCCCCCCCHHHHHHH
GHEICGEIVGLGKNIADLKNGQQVAVIPYVACQQCPACKSGRTNCCEKISVIGVHQDGGF
HHHHHHHHHHCCCCHHHHCCCCEEEEEEHHHHCCCCCCCCCCCHHHHEEEEEEEECCCCH
SEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAIAPGEQVLVVGAGPIGLGAAA
HHHHHCCHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHH
IAKADGAQVVVADTSPARREHVATRLELPLLDPSAEDFDAQLRAQFGGSLAQKVIDATGN
HHCCCCCEEEEECCCCHHHHHHHHHEECCCCCCCCCCHHHHHHHHHCHHHHHHHHHCCCC
QHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHKKETTMMGSRNATPEDFAKVGRLMA
CHHHHHHHHHHCCCCEEEEEEEEECEEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
EGKITADMMLTHRYPFATLAETYERDVINNRELIKGVITF
CCCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503