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The map label for this gene is nsrR

Identifier: 157163642

GI number: 157163642

Start: 4430926

End: 4431351

Strand: Direct

Name: nsrR

Synonym: EcHS_A4421

Alternate gene names: 157163642

Gene position: 4430926-4431351 (Clockwise)

Preceding gene: 157163641

Following gene: 157163643

Centisome position: 95.42

GC content: 48.59

Gene sequence:

>426_bases
GTGCAGTTAACGAGTTTCACTGATTACGGATTACGTGCGCTGATCTACATGGCGTCATTGCCAGAAGGGCGGATGACCAG
TATTTCTGAAGTGACTGACGTCTACGGCGTCTCCCGTAATCATATGGTCAAAATAATCAATCAACTTAGTCGTGCCGGCT
ACGTGACTGCTGTTCGTGGAAAAAATGGCGGCATTCGCCTGGGTAAATCGGCGAGTGCGATACGTATTGGTGATGTGGTG
CGCGAGCTGGAGCCCTTATCGCTGGTGAATTGCAGCAGTGAGTTTTGCCACATTACACCTGCCTGTCGGTTGAAACAGGC
GCTTTCTAAGGCCGTGCAAAGTTTTCTTACGGAACTGGATAACTACACGCTTGCCGATTTGGTTGAAGAGAATCAACCGC
TTTATAAATTATTGCTGGTGGAGTGA

Upstream 100 bases:

>100_bases
TTTTTCCTTCCCCGAACTGAAATAAATTAGCGACACAGCTTGTGGCTGGTTTATCATCAATATAAATGTATTTTTTCCCG
ATTTCCCTTTTGAGGTTGAT

Downstream 100 bases:

>100_bases
CGAAAATCTTCATCAGAGATGACAACGGAGGAACCGAGATGTCACAAGATCCTTTCCAGGAACGCGAAGCTGAAAAATAC
GCGAATCCCATCCCTAGTCG

Product: transcriptional repressor NsrR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVKIINQLSRAGYVTAVRGKNGGIRLGKSASAIRIGDVV
RELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE

Sequences:

>Translated_141_residues
MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVKIINQLSRAGYVTAVRGKNGGIRLGKSASAIRIGDVV
RELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE
>Mature_141_residues
MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVKIINQLSRAGYVTAVRGKNGGIRLGKSASAIRIGDVV
RELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE

Specific function: Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1790621, Length=141, Percent_Identity=99.290780141844, Blast_Score=288, Evalue=1e-79,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NSRR_ECO24 (A7ZV48)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001465677.1
- ProteinModelPortal:   A7ZV48
- STRING:   A7ZV48
- EnsemblBacteria:   EBESCT00000022406
- GeneID:   5588542
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_4737
- eggNOG:   COG1959
- GeneTree:   EBGT00050000009265
- HOGENOM:   HBG725923
- OMA:   VMAVRGK
- ProtClustDB:   PRK11014
- BioCyc:   ECOL331111:ECE24377A_4737-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_01177
- InterPro:   IPR000944
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- TIGRFAMs:   TIGR00738

Pfam domain/function: PF02082 Rrf2

EC number: NA

Molecular weight: Translated: 15583; Mature: 15583

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS01332 HTH_RRF2_1; PS51197 HTH_RRF2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVKIINQLSRAGYVTAVRG
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEC
KNGGIRLGKSASAIRIGDVVRELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLTELD
CCCCEEECCCCCHHHHHHHHHHCCCCCEECCCCCCEECCHHHHHHHHHHHHHHHHHHHHC
NYTLADLVEENQPLYKLLLVE
CCHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure
MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVKIINQLSRAGYVTAVRG
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEC
KNGGIRLGKSASAIRIGDVVRELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLTELD
CCCCEEECCCCCHHHHHHHHHHCCCCCEECCCCCCEECCHHHHHHHHHHHHHHHHHHHHC
NYTLADLVEENQPLYKLLLVE
CCHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA