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The map label for this gene is mreC

Identifier: 157162727

GI number: 157162727

Start: 3442463

End: 3443566

Strand: Reverse

Name: mreC

Synonym: EcHS_A3439

Alternate gene names: 157162727

Gene position: 3443566-3442463 (Counterclockwise)

Preceding gene: 157162728

Following gene: 157162726

Centisome position: 74.16

GC content: 55.98

Gene sequence:

>1104_bases
ATGAAGCCAATTTTTAGCCGTGGCCCGTCGCTACAGATTCGCCTTATTCTGGCGGTGCTGGTGGCGCTCGGCATTATTAT
TGCCGACAGCCGCCTGGGGACGTTCAGTCAAATCCGTACTTATATGGATACCGCCGTCAGTCCTTTCTACTTTGTTTCCA
ATGCTCCTCGTGAATTGCTGGATGGCGTATCGCAGACGCTGGCCTCGCGTGACCAATTAGAACTTGAAAACCGGGCGTTA
CGTCAGGAACTGTTGCTGAAAAACAGTGAACTGCTGATGCTTGGACAATACAAACAGGAGAACGCGCGTCTGCGCGAGCT
GCTGGGTTCCCCGCTGCGTCAGGATGAGCAGAAAATGGTGACTCAGGTTATCTCCACGGTTAACGATCCTTATAGCGATC
AAGTTGTTATCGATAAAGGTAGCGTTAATGGCGTTTATGAAGGCCAGCCGGTCATCAGCGACAAAGGTGTTGTTGGTCAG
GTGGTGGCCGTCGCTAAACTGACCAGTCGCGTGCTGCTGATTTGTGATGCGACCCACGCGCTGCCAATCCAGGTGCTGCG
CAACGATATCCGCGTAATTGCAGCCGGTAACGGTTGTACGGATGATTTGCAGCTTGAGCATCTGCCGGCGAATACGGATA
TTCGTGTTGGTGATGTGCTGGTGACTTCCGGTCTGGGCGGTCGTTTCCCGGAAGGCTATCCGGTCGCGGTTGTCTCTTCC
GTAAAACTCGATACCCAGCGCGCTTATACTGTGATTCAGGCGCGTCCGACTGCAGGGCTGCAACGTTTGCGTTATCTGCT
GCTGCTGTGGGGGGCAGATCGTAACGGCGCTAACCCGATGACGCCGGAAGAGGTGCATCGTGTTGCTAATGAACGTCTGA
TGCAGATGATGCCGCAGGTATTGCCTTCGCCAGACGCGATGGGGCCAAAGTTACCTGAACCGGCAACGGGGATCGCTCAG
CCGACTCCGCAGCAACCGGCGACAGGAAATGCAGCTACTGCGCCTGCTGCGCCGACACAGCCTGCTGCTAATCGCTCTCC
ACAAAGGGCTACGCCGCCGCAAAGTGGTGCTCAACCGCCTGCGCGTGCGCCGGGAGGGCAATAG

Upstream 100 bases:

>100_bases
ACATGCACGGCGGCGACCTGTTCAGCGAAGAGTAATCGGATGCAGGCAGGGGAAGTGTCTGTTTACCCTGCCTGGTCTGA
TACGAGAATACGCATAACTT

Downstream 100 bases:

>100_bases
TGGCGAGCTATCGTAGCCAGGGACGCTGGGTAATCTGGCTCTCTTTCCTCATTGCGCTGTTGCTGCAAATCATGCCCTGG
CCGGATAACCTGATTTTTTT

Product: rod shape-determining protein MreC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MKPIFSRGPSLQIRLILAVLVALGIIIADSRLGTFSQIRTYMDTAVSPFYFVSNAPRELLDGVSQTLASRDQLELENRAL
RQELLLKNSELLMLGQYKQENARLRELLGSPLRQDEQKMVTQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQ
VVAVAKLTSRVLLICDATHALPIQVLRNDIRVIAAGNGCTDDLQLEHLPANTDIRVGDVLVTSGLGGRFPEGYPVAVVSS
VKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNGANPMTPEEVHRVANERLMQMMPQVLPSPDAMGPKLPEPATGIAQ
PTPQQPATGNAATAPAAPTQPAANRSPQRATPPQSGAQPPARAPGGQ

Sequences:

>Translated_367_residues
MKPIFSRGPSLQIRLILAVLVALGIIIADSRLGTFSQIRTYMDTAVSPFYFVSNAPRELLDGVSQTLASRDQLELENRAL
RQELLLKNSELLMLGQYKQENARLRELLGSPLRQDEQKMVTQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQ
VVAVAKLTSRVLLICDATHALPIQVLRNDIRVIAAGNGCTDDLQLEHLPANTDIRVGDVLVTSGLGGRFPEGYPVAVVSS
VKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNGANPMTPEEVHRVANERLMQMMPQVLPSPDAMGPKLPEPATGIAQ
PTPQQPATGNAATAPAAPTQPAANRSPQRATPPQSGAQPPARAPGGQ
>Mature_367_residues
MKPIFSRGPSLQIRLILAVLVALGIIIADSRLGTFSQIRTYMDTAVSPFYFVSNAPRELLDGVSQTLASRDQLELENRAL
RQELLLKNSELLMLGQYKQENARLRELLGSPLRQDEQKMVTQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQ
VVAVAKLTSRVLLICDATHALPIQVLRNDIRVIAAGNGCTDDLQLEHLPANTDIRVGDVLVTSGLGGRFPEGYPVAVVSS
VKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNGANPMTPEEVHRVANERLMQMMPQVLPSPDAMGPKLPEPATGIAQ
PTPQQPATGNAATAPAAPTQPAANRSPQRATPPQSGAQPPARAPGGQ

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins

COG id: COG1792

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Inner Membrane-Anchored [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreC family

Homologues:

Organism=Escherichia coli, GI1789648, Length=367, Percent_Identity=100, Blast_Score=737, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MREC_ECOLI (P16926)

Other databases:

- EMBL:   M31792
- EMBL:   U18997
- EMBL:   U00096
- EMBL:   AP009048
- EMBL:   M22055
- PIR:   JV0059
- RefSeq:   AP_003791.1
- RefSeq:   NP_417716.1
- ProteinModelPortal:   P16926
- SMR:   P16926
- DIP:   DIP-10256N
- MINT:   MINT-7012243
- STRING:   P16926
- EnsemblBacteria:   EBESCT00000001839
- EnsemblBacteria:   EBESCT00000001840
- EnsemblBacteria:   EBESCT00000001841
- EnsemblBacteria:   EBESCT00000014491
- GeneID:   947655
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW3219
- KEGG:   eco:b3250
- EchoBASE:   EB0604
- EcoGene:   EG10609
- eggNOG:   COG1792
- GeneTree:   EBGT00050000009738
- HOGENOM:   HBG751983
- OMA:   NPFTHRI
- ProtClustDB:   PRK13922
- BioCyc:   EcoCyc:EG10609-MONOMER
- Genevestigator:   P16926
- InterPro:   IPR007221
- InterPro:   IPR005223
- TIGRFAMs:   TIGR00219

Pfam domain/function: PF04085 MreC

EC number: NA

Molecular weight: Translated: 39531; Mature: 39531

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPIFSRGPSLQIRLILAVLVALGIIIADSRLGTFSQIRTYMDTAVSPFYFVSNAPRELL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEECCCHHHHH
DGVSQTLASRDQLELENRALRQELLLKNSELLMLGQYKQENARLRELLGSPLRQDEQKMV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHHH
TQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQVVAVAKLTSRVLLICDATHA
HHHHHHHCCCCCCEEEEECCCCCCEECCCCCCCCCCHHHHHHHHHHHHHCEEEEECCCCH
LPIQVLRNDIRVIAAGNGCTDDLQLEHLPANTDIRVGDVLVTSGLGGRFPEGYPVAVVSS
HHHHHHHCCEEEEECCCCCCCCCEEEECCCCCCEEECCEEEECCCCCCCCCCCCEEEEEE
VKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNGANPMTPEEVHRVANERLMQMMPQV
EEECHHHHEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LPSPDAMGPKLPEPATGIAQPTPQQPATGNAATAPAAPTQPAANRSPQRATPPQSGAQPP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ARAPGGQ
CCCCCCC
>Mature Secondary Structure
MKPIFSRGPSLQIRLILAVLVALGIIIADSRLGTFSQIRTYMDTAVSPFYFVSNAPRELL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEECCCHHHHH
DGVSQTLASRDQLELENRALRQELLLKNSELLMLGQYKQENARLRELLGSPLRQDEQKMV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHHH
TQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQVVAVAKLTSRVLLICDATHA
HHHHHHHCCCCCCEEEEECCCCCCEECCCCCCCCCCHHHHHHHHHHHHHCEEEEECCCCH
LPIQVLRNDIRVIAAGNGCTDDLQLEHLPANTDIRVGDVLVTSGLGGRFPEGYPVAVVSS
HHHHHHHCCEEEEECCCCCCCCCEEEECCCCCCEEECCEEEECCCCCCCCCCCCEEEEEE
VKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNGANPMTPEEVHRVANERLMQMMPQV
EEECHHHHEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LPSPDAMGPKLPEPATGIAQPTPQQPATGNAATAPAAPTQPAANRSPQRATPPQSGAQPP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ARAPGGQ
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2687239; 9278503; 3049542