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The map label for this gene is lytS [H]

Identifier: 157162726

GI number: 157162726

Start: 3441975

End: 3442463

Strand: Reverse

Name: lytS [H]

Synonym: EcHS_A3438

Alternate gene names: 157162726

Gene position: 3442463-3441975 (Counterclockwise)

Preceding gene: 157162727

Following gene: 157162725

Centisome position: 74.13

GC content: 51.12

Gene sequence:

>489_bases
GTGGCGAGCTATCGTAGCCAGGGACGCTGGGTAATCTGGCTCTCTTTCCTCATTGCGCTGTTGCTGCAAATCATGCCCTG
GCCGGATAACCTGATTTTTTTCCGGCCAAACTGGGTGTTACTCATCTTGTTGTATTGGATCCTGGCCTTGCCTCATCGCG
TAAATGTGGGCACAGGTTTTGTGATGGGTGCCATACTGGATCTGATCAGCGGCTCGACGCTTGGCGTACGCGTATTGGCG
ATGAGCATCATTGCTTACCTGGTGGCGCTGAAATACCAGCTTTTCCGCAACCTCGCATTATGGCAGCAGGCGCTGGTCGT
CATGTTGCTTTCGCTGGTGGTGGATATTATTGTTTTCTGGGCAGAGTTTTTAGTGATTAACGTCTCTTTCAGACCGGAAG
TGTTCTGGAGTAGTGTAGTCAATGGGGTGCTCTGGCCGTGGATTTTCTTGCTGATGCGCAAAGTCCGTCAGCAGTTTGCA
GTGCAATAA

Upstream 100 bases:

>100_bases
CTGCTGCGCCGACACAGCCTGCTGCTAATCGCTCTCCACAAAGGGCTACGCCGCCGCAAAGTGGTGCTCAACCGCCTGCG
CGTGCGCCGGGAGGGCAATA

Downstream 100 bases:

>100_bases
AGGTTTCTATGACTTCTCTGTATTTAGCTTCCGGTTCTCCGCGTCGTCAGGAGTTACTTGCGCAACTTGGCGTGACCTTT
GAACGTATTGTTACGGGCAT

Product: rod shape-determining protein MreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MASYRSQGRWVIWLSFLIALLLQIMPWPDNLIFFRPNWVLLILLYWILALPHRVNVGTGFVMGAILDLISGSTLGVRVLA
MSIIAYLVALKYQLFRNLALWQQALVVMLLSLVVDIIVFWAEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFA
VQ

Sequences:

>Translated_162_residues
MASYRSQGRWVIWLSFLIALLLQIMPWPDNLIFFRPNWVLLILLYWILALPHRVNVGTGFVMGAILDLISGSTLGVRVLA
MSIIAYLVALKYQLFRNLALWQQALVVMLLSLVVDIIVFWAEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFA
VQ
>Mature_161_residues
ASYRSQGRWVIWLSFLIALLLQIMPWPDNLIFFRPNWVLLILLYWILALPHRVNVGTGFVMGAILDLISGSTLGVRVLAM
SIIAYLVALKYQLFRNLALWQQALVVMLLSLVVDIIVFWAEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFAV
Q

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG2891

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreD family [H]

Homologues:

Organism=Escherichia coli, GI1789647, Length=162, Percent_Identity=99.3827160493827, Blast_Score=308, Evalue=8e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007227 [H]

Pfam domain/function: PF04093 MreD [H]

EC number: NA

Molecular weight: Translated: 18836; Mature: 18705

Theoretical pI: Translated: 10.98; Mature: 10.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASYRSQGRWVIWLSFLIALLLQIMPWPDNLIFFRPNWVLLILLYWILALPHRVNVGTGF
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHH
VMGAILDLISGSTLGVRVLAMSIIAYLVALKYQLFRNLALWQQALVVMLLSLVVDIIVFW
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFAVQ
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASYRSQGRWVIWLSFLIALLLQIMPWPDNLIFFRPNWVLLILLYWILALPHRVNVGTGF
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHH
VMGAILDLISGSTLGVRVLAMSIIAYLVALKYQLFRNLALWQQALVVMLLSLVVDIIVFW
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFAVQ
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]