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The map label for this gene is yhcC

Identifier: 157162695

GI number: 157162695

Start: 3404048

End: 3404977

Strand: Reverse

Name: yhcC

Synonym: EcHS_A3404

Alternate gene names: 157162695

Gene position: 3404977-3404048 (Counterclockwise)

Preceding gene: 157162700

Following gene: 157162694

Centisome position: 73.33

GC content: 56.13

Gene sequence:

>930_bases
ATGCAGTTACAGAAATTAGTCAATATGTTTGGTGGTGATCTCACCCGTCGTTATGGGCAAAAGGTGCATAAGCTGACGCT
GCACGGCGGTTTTAGCTGCCCTAACCGTGACGGCACCATCGGGCGTGGTGGCTGCACATTCTGTAATGTTGCCTCGTTTG
CCGATGAAGCGCAGCAGCATCGTTCCATTGCCGAGCAACTGGCGCACCAGGCGAATTTAGTTAACCGCGCTAAACGCTAT
CTGGCCTACTTTCAGGCGTATACCAGCACCTTTGCGGAAGTTCAGGTGCTGCGTTCTATGTATCAGCAGGCGGTGAGCCA
GGCCAATATTGTCGGTTTGTGTGTGGGTACCCGCCCGGACTGCGTGCCGGATGCGGTGCTGGATCTGCTTTGCGAATATA
AGGACCAGGGTTACGAAGTGTGGCTGGAGCTGGGGCTACAAACCGCCCACGACAAAACACTGCATCGCATCAACCGCGGC
CATGATTTTGCCTGTTATCAGCGTACAACCCAGCTGGCACGTCAGCGCGGGCTGAAGGTGTGTTCCCACTTAATTGTCGG
CCTGCCTGGCGAAGGGCAGGCTGAATGTTTGCAAACGCTGGAGCGAGTGGTTGAAACCGGCGTGGACGGCATAAAGCTGC
ATCCGCTGCATATTGTGAAAGGCAGCATTATGGCGAAAGCCTGGGAAGCGGGGCGTTTGAACGGTATTGAACTGGAGGAT
TACACGCTCACTGCCGGAGAAATGATTCGCCATACGCCACCGGAAGTGATCTACCACCGCATTTCCGCCAGCGCCCGTCG
CCCGACGCTGCTTGCTCCGCTGTGGTGCGAAAATCGATGGACGGGAATGGTCGAGCTGGATCGCTATCTGAATGAACATG
GCGTACAGGGATCGGCGCTGGGACGTCCGTGGCTACCTCCAACGGAGTAG

Upstream 100 bases:

>100_bases
AGTTGATAAAAGCAGGCCGGGACGATTGATCCAGGTCATCGCCGAATTGAGCTAAAAATGGCAGGCTTTGGCCTCTTTTC
AAGGCGCGGTCTATCAGATT

Downstream 100 bases:

>100_bases
GTCGTTGAGGGGAATTCCGCATTTCTCACACAATTTATAACGTAACTGTCAGAATTGGGTATTATTGGGGCAGGTTGTCG
TGAAGGAATTCCCTAATGAA

Product: radical SAM family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MQLQKLVNMFGGDLTRRYGQKVHKLTLHGGFSCPNRDGTIGRGGCTFCNVASFADEAQQHRSIAEQLAHQANLVNRAKRY
LAYFQAYTSTFAEVQVLRSMYQQAVSQANIVGLCVGTRPDCVPDAVLDLLCEYKDQGYEVWLELGLQTAHDKTLHRINRG
HDFACYQRTTQLARQRGLKVCSHLIVGLPGEGQAECLQTLERVVETGVDGIKLHPLHIVKGSIMAKAWEAGRLNGIELED
YTLTAGEMIRHTPPEVIYHRISASARRPTLLAPLWCENRWTGMVELDRYLNEHGVQGSALGRPWLPPTE

Sequences:

>Translated_309_residues
MQLQKLVNMFGGDLTRRYGQKVHKLTLHGGFSCPNRDGTIGRGGCTFCNVASFADEAQQHRSIAEQLAHQANLVNRAKRY
LAYFQAYTSTFAEVQVLRSMYQQAVSQANIVGLCVGTRPDCVPDAVLDLLCEYKDQGYEVWLELGLQTAHDKTLHRINRG
HDFACYQRTTQLARQRGLKVCSHLIVGLPGEGQAECLQTLERVVETGVDGIKLHPLHIVKGSIMAKAWEAGRLNGIELED
YTLTAGEMIRHTPPEVIYHRISASARRPTLLAPLWCENRWTGMVELDRYLNEHGVQGSALGRPWLPPTE
>Mature_309_residues
MQLQKLVNMFGGDLTRRYGQKVHKLTLHGGFSCPNRDGTIGRGGCTFCNVASFADEAQQHRSIAEQLAHQANLVNRAKRY
LAYFQAYTSTFAEVQVLRSMYQQAVSQANIVGLCVGTRPDCVPDAVLDLLCEYKDQGYEVWLELGLQTAHDKTLHRINRG
HDFACYQRTTQLARQRGLKVCSHLIVGLPGEGQAECLQTLERVVETGVDGIKLHPLHIVKGSIMAKAWEAGRLNGIELED
YTLTAGEMIRHTPPEVIYHRISASARRPTLLAPLWCENRWTGMVELDRYLNEHGVQGSALGRPWLPPTE

Specific function: Unknown

COG id: COG1242

COG function: function code R; Predicted Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To M.jannaschii MJ0486

Homologues:

Organism=Homo sapiens, GI23510283, Length=170, Percent_Identity=24.7058823529412, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI2367204, Length=309, Percent_Identity=100, Blast_Score=644, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325171, Length=174, Percent_Identity=23.5632183908046, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHCC_ECO57 (P0ADW7)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   B91140
- PIR:   E85985
- RefSeq:   NP_289785.1
- RefSeq:   NP_312117.1
- ProteinModelPortal:   P0ADW7
- MINT:   MINT-1252669
- EnsemblBacteria:   EBESCT00000028052
- EnsemblBacteria:   EBESCT00000056984
- GeneID:   916061
- GeneID:   958652
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z4575
- KEGG:   ecs:ECs4090
- GeneTree:   EBGT00050000010705
- HOGENOM:   HBG359185
- OMA:   HVILGLP
- ProtClustDB:   CLSK862206
- BioCyc:   ECOL83334:ECS4090-MONOMER
- InterPro:   IPR005911
- InterPro:   IPR006638
- InterPro:   IPR007197
- SMART:   SM00729
- TIGRFAMs:   TIGR01212

Pfam domain/function: PF04055 Radical_SAM

EC number: NA

Molecular weight: Translated: 34607; Mature: 34607

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLQKLVNMFGGDLTRRYGQKVHKLTLHGGFSCPNRDGTIGRGGCTFCNVASFADEAQQH
CCHHHHHHHHCCHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RSIAEQLAHQANLVNRAKRYLAYFQAYTSTFAEVQVLRSMYQQAVSQANIVGLCVGTRPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCC
CVPDAVLDLLCEYKDQGYEVWLELGLQTAHDKTLHRINRGHDFACYQRTTQLARQRGLKV
CCHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
CSHLIVGLPGEGQAECLQTLERVVETGVDGIKLHPLHIVKGSIMAKAWEAGRLNGIELED
HHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHCCCCCCCEECC
YTLTAGEMIRHTPPEVIYHRISASARRPTLLAPLWCENRWTGMVELDRYLNEHGVQGSAL
EEECHHHHHHCCCHHHHHHHHHCCCCCCCEECEECCCCCCCHHHHHHHHHHHHCCCCCCC
GRPWLPPTE
CCCCCCCCC
>Mature Secondary Structure
MQLQKLVNMFGGDLTRRYGQKVHKLTLHGGFSCPNRDGTIGRGGCTFCNVASFADEAQQH
CCHHHHHHHHCCHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
RSIAEQLAHQANLVNRAKRYLAYFQAYTSTFAEVQVLRSMYQQAVSQANIVGLCVGTRPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCC
CVPDAVLDLLCEYKDQGYEVWLELGLQTAHDKTLHRINRGHDFACYQRTTQLARQRGLKV
CCHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
CSHLIVGLPGEGQAECLQTLERVVETGVDGIKLHPLHIVKGSIMAKAWEAGRLNGIELED
HHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHCCCCCCCEECC
YTLTAGEMIRHTPPEVIYHRISASARRPTLLAPLWCENRWTGMVELDRYLNEHGVQGSAL
EEECHHHHHHCCCHHHHHHHHHCCCCCCCEECEECCCCCCCHHHHHHHHHHHHCCCCCCC
GRPWLPPTE
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796