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The map label for this gene is intZ [H]

Identifier: 157161980

GI number: 157161980

Start: 2667104

End: 2668291

Strand: Reverse

Name: intZ [H]

Synonym: EcHS_A2656

Alternate gene names: 157161980

Gene position: 2668291-2667104 (Counterclockwise)

Preceding gene: 157161981

Following gene: 157161976

Centisome position: 57.46

GC content: 47.47

Gene sequence:

>1188_bases
ATGTTGACTGACACCAGGCTGCGTCACCTTAAGCCGAAGGAGAAACTCTATAAAGTTAATGACCGTGATGGTCTGTATGT
TGCGGTCACTCCGGCTGGAACGATCTCATTTCGTTATAACTATTCAATAAACGGAAGACAGGAGACCGTTACTTTTGGCC
GCTATGGTGTGGGAGGGATCACGCTTGCAGAAGCGCGTGAACGGCTCAATGAAGCTAAAAAAATGGTTGCCGGTGGAAGA
TCTCCAGCGAGGGAAAAAGCTAGAGATAAAGCGCGTATCAAAGATGCGGAGACTTTTGGTGCATGGGCTGAGAAATGGTT
ACGCGGCTATCAAATGGCTGAATCGACGCGTGATATGCGGCGTTCGGTATATCAAAGGGAGTTGAAGTCTAAATTTGCGC
AGCAGAAATTGGCCGAGATTACACATGAAGACTTACGCGCATTAACCGATAACATTGTCGAGAGAGGGGCACCGGCGACA
GCTGTACACGCCAGAGAGATTGTATTGCAAGTCTATCGCTGGGCTATTGAGCGCGGTCAGAAGGTTGAGAATCCCGCTGA
TCTGGTACGGCCTGCAAGCATAGCGAAATTTGAGCCTCGTGACAGGGCATTGACGCCAGTTGAAATTGGTCTGATGTATC
GGTACATGGAACGGGTAGGAACGACGCCATCAATCAGAGCAGCGGTTAAACTTTTGCTGTTAACGATGGTACGTAAAAGT
GAGCTTACTAACGCAACCTGGAACGAGATCAATTTTAGTGAAGCATTATGGACGATACCAAAGGAGAGGATGAAAAGACG
TAATCCACATTTGGTTTTTCTTTCCAGACAGGCAATGGATATCATGATTGCTCTCAAAACTTTTGCCGGTAGCTCTGATT
TTATCCTTCCTTCGCGGTACGATTCCGATGCGCCTATGAGTAGTGCTACTTTAAACCGGGTTTTGACCTTGACGTATCGC
CTGGCACAGAAAGAAGGGGAGTCATTGCCGAAGTTTGGTCCTCATGACTTACGGCGTACAGCCAGCACTTTGCTACATGA
GGCCGGGTACAATACTGACTGGATCGAAAAATGCCTGGCACATGAACAGAAAGGGGTTAGGGCGGTATACAACAAAGCTG
AATATCGAGAGCAAAGAGCATCAATGCTACAGGATTGGGCTGATATGATAGATGAATGGGTTGCGTAA

Upstream 100 bases:

>100_bases
ATGGTATTTGTTTTTATAAATCGATTAAAAACAGATAGTTAAATAAATTTTCTGAATTTTTTACAACATGGTATTTTTTG
ATAAAGGAAAACAATAAATC

Downstream 100 bases:

>100_bases
TGTGTGAGCTTAAACTTAGTTTGACACTCTACGGAAAGAGCTAGCTAAATTTGACAGGATGCTCGATGCCGGGAGCAGAT
GTTTCCGACATCAGTTTATG

Product: phage integrase family site specific recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MLTDTRLRHLKPKEKLYKVNDRDGLYVAVTPAGTISFRYNYSINGRQETVTFGRYGVGGITLAEARERLNEAKKMVAGGR
SPAREKARDKARIKDAETFGAWAEKWLRGYQMAESTRDMRRSVYQRELKSKFAQQKLAEITHEDLRALTDNIVERGAPAT
AVHAREIVLQVYRWAIERGQKVENPADLVRPASIAKFEPRDRALTPVEIGLMYRYMERVGTTPSIRAAVKLLLLTMVRKS
ELTNATWNEINFSEALWTIPKERMKRRNPHLVFLSRQAMDIMIALKTFAGSSDFILPSRYDSDAPMSSATLNRVLTLTYR
LAQKEGESLPKFGPHDLRRTASTLLHEAGYNTDWIEKCLAHEQKGVRAVYNKAEYREQRASMLQDWADMIDEWVA

Sequences:

>Translated_395_residues
MLTDTRLRHLKPKEKLYKVNDRDGLYVAVTPAGTISFRYNYSINGRQETVTFGRYGVGGITLAEARERLNEAKKMVAGGR
SPAREKARDKARIKDAETFGAWAEKWLRGYQMAESTRDMRRSVYQRELKSKFAQQKLAEITHEDLRALTDNIVERGAPAT
AVHAREIVLQVYRWAIERGQKVENPADLVRPASIAKFEPRDRALTPVEIGLMYRYMERVGTTPSIRAAVKLLLLTMVRKS
ELTNATWNEINFSEALWTIPKERMKRRNPHLVFLSRQAMDIMIALKTFAGSSDFILPSRYDSDAPMSSATLNRVLTLTYR
LAQKEGESLPKFGPHDLRRTASTLLHEAGYNTDWIEKCLAHEQKGVRAVYNKAEYREQRASMLQDWADMIDEWVA
>Mature_395_residues
MLTDTRLRHLKPKEKLYKVNDRDGLYVAVTPAGTISFRYNYSINGRQETVTFGRYGVGGITLAEARERLNEAKKMVAGGR
SPAREKARDKARIKDAETFGAWAEKWLRGYQMAESTRDMRRSVYQRELKSKFAQQKLAEITHEDLRALTDNIVERGAPAT
AVHAREIVLQVYRWAIERGQKVENPADLVRPASIAKFEPRDRALTPVEIGLMYRYMERVGTTPSIRAAVKLLLLTMVRKS
ELTNATWNEINFSEALWTIPKERMKRRNPHLVFLSRQAMDIMIALKTFAGSSDFILPSRYDSDAPMSSATLNRVLTLTYR
LAQKEGESLPKFGPHDLRRTASTLLHEAGYNTDWIEKCLAHEQKGVRAVYNKAEYREQRASMLQDWADMIDEWVA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=403, Percent_Identity=34.7394540942928, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1788974, Length=402, Percent_Identity=30.5970149253731, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788690, Length=396, Percent_Identity=27.5252525252525, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 45331; Mature: 45331

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDTRLRHLKPKEKLYKVNDRDGLYVAVTPAGTISFRYNYSINGRQETVTFGRYGVGGI
CCCCCHHHHCCCHHHHEEECCCCCEEEEEECCCEEEEEEEEEECCCCEEEEECCCCCCCE
TLAEARERLNEAKKMVAGGRSPAREKARDKARIKDAETFGAWAEKWLRGYQMAESTRDMR
EHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSVYQRELKSKFAQQKLAEITHEDLRALTDNIVERGAPATAVHAREIVLQVYRWAIERGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
KVENPADLVRPASIAKFEPRDRALTPVEIGLMYRYMERVGTTPSIRAAVKLLLLTMVRKS
CCCCHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ELTNATWNEINFSEALWTIPKERMKRRNPHLVFLSRQAMDIMIALKTFAGSSDFILPSRY
HHCCCCCCCCCHHHHHHHCCHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCC
DSDAPMSSATLNRVLTLTYRLAQKEGESLPKFGPHDLRRTASTLLHEAGYNTDWIEKCLA
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
HEQKGVRAVYNKAEYREQRASMLQDWADMIDEWVA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLTDTRLRHLKPKEKLYKVNDRDGLYVAVTPAGTISFRYNYSINGRQETVTFGRYGVGGI
CCCCCHHHHCCCHHHHEEECCCCCEEEEEECCCEEEEEEEEEECCCCEEEEECCCCCCCE
TLAEARERLNEAKKMVAGGRSPAREKARDKARIKDAETFGAWAEKWLRGYQMAESTRDMR
EHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSVYQRELKSKFAQQKLAEITHEDLRALTDNIVERGAPATAVHAREIVLQVYRWAIERGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCC
KVENPADLVRPASIAKFEPRDRALTPVEIGLMYRYMERVGTTPSIRAAVKLLLLTMVRKS
CCCCHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ELTNATWNEINFSEALWTIPKERMKRRNPHLVFLSRQAMDIMIALKTFAGSSDFILPSRY
HHCCCCCCCCCHHHHHHHCCHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCC
DSDAPMSSATLNRVLTLTYRLAQKEGESLPKFGPHDLRRTASTLLHEAGYNTDWIEKCLA
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
HEQKGVRAVYNKAEYREQRASMLQDWADMIDEWVA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]