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The map label for this gene is mntH [H]

Identifier: 157161865

GI number: 157161865

Start: 2542870

End: 2544108

Strand: Reverse

Name: mntH [H]

Synonym: EcHS_A2529

Alternate gene names: 157161865

Gene position: 2544108-2542870 (Counterclockwise)

Preceding gene: 157161867

Following gene: 157161861

Centisome position: 54.79

GC content: 52.78

Gene sequence:

>1239_bases
ATGACGAACTATCGCGTTGAGAGTAGCAGCGGACGGGCGGCGCGCAAGACGAGGCTCGCATTAATGGGACCTGCGTTCAT
TGCGGCGATTGGTTATATCGATCCCGGTAACTTTGCGACCAATATTCAGGCGGGTGCCAGCTTCGGCTATCAGCTCCTGT
GGGTTGTCGTTTGGGCCAACCTGATGGCGATGTTGATTCAGATCCTCTCTGCCAAACTAGGGATTGCCACCGGTAAAAAT
CTGGCGGAGCAAATTCGCGATCACTATCCGCGTCCCGTAGTGTGGTTCTATTGGGTTCAGGCAGAAATTATTGCGATGGC
AACCGACCTGGCGGAATTTATTGGTGCGGCGATCGGTTTTAAACTCATTCTTGGTGTTTCGTTGTTGCAAGGTGCGGTGC
TGACGGGGATCGCGACTTTCCTGATTTTAATGCTGCAACGTCGCGGGCAAAAACCGCTGGAGAAAGTGATTGGCGGGTTA
CTGTTGTTTGTTGCCGCGGCTTACATTGTCGAGTTGATTTTCTCCCAGCCTAACCTGGCGCAGCTGGGTAAAGGAATGGT
GATCCCGAGTTTACCTACTTCGGAAGCGGTCTTCCTTGCAGCAGGCGTGTTAGGGGCGACGATTATGCCGCATGTGATTT
ATTTGCACTCTTCGCTCACTCAGCATTTACATGGCGGTTCGCGTCAACAACGTTATTCCGCCACCAAATGGGATGTGGCT
ATCGCCATGACTATTGCCGGTTTTGTCAATCTGGCGATGATGGCTACAGCTGCGGCGGCGTTCCACTTTTCTGGTCATAC
TGGTGTTGCCGATCTTGATGAGGCATATCTGACGCTGCAACCGTTGTTAAGCCATGCTGCGGCAACGGTCTTTGGATTAA
GCCTGGTTGCTGCCGGACTGTCCTCAACGGTGGTGGGGACACTGGCGGGGCAGGTGGTGATGCAGGGGTTCATTCGCTTC
CATATCCCGCTGTGGGTGCGTCGTACAGTCACCATGTTGCCGTCATTTATTGTCATTCTGATGGGATTAGATCCGACACG
GATTCTGGTTATGAGTCAGGTGCTGTTAAGTTTTGGTATCGCCCTGGCGCTGGTTCCACTGCTGATTTTCACCAGTGACA
GCAAGTTGATGGGCGATCTGGTGAACAGCAAACGCGTAAAACAGACAGGCTGGGTGATTGTGGTGCTGGTAGTGGCGCTG
AATATCTGGTTGTTGGTGGGTACGGCACTGGGATTGTAG

Upstream 100 bases:

>100_bases
CTATCAAAGAAATCACCACAACCCATTTAAATGAATTTGATAATCATTCTCGTTTGGCATAGCATGAAACATAGCAAAGG
CTATGTTTTAGAGGCACAAG

Downstream 100 bases:

>100_bases
TTGAATGAGCGTCGCATCTGGCACTATTGGCGGATGCGGCGTAAACGCCTTACCCGCCCTACGCGTTAAAGAGCCGGTTT
GTAGGCCTGATAAGACGCGC

Product: manganese transport protein MntH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MTNYRVESSSGRAARKTRLALMGPAFIAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKN
LAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGL
LLFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGSRQQRYSATKWDVA
IAMTIAGFVNLAMMATAAAAFHFSGHTGVADLDEAYLTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRF
HIPLWVRRTVTMLPSFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWVIVVLVVAL
NIWLLVGTALGL

Sequences:

>Translated_412_residues
MTNYRVESSSGRAARKTRLALMGPAFIAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKN
LAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGL
LLFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGSRQQRYSATKWDVA
IAMTIAGFVNLAMMATAAAAFHFSGHTGVADLDEAYLTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRF
HIPLWVRRTVTMLPSFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWVIVVLVVAL
NIWLLVGTALGL
>Mature_411_residues
TNYRVESSSGRAARKTRLALMGPAFIAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNL
AEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGLL
LFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGSRQQRYSATKWDVAI
AMTIAGFVNLAMMATAAAAFHFSGHTGVADLDEAYLTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRFH
IPLWVRRTVTMLPSFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWVIVVLVVALN
IWLLVGTALGL

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=439, Percent_Identity=31.4350797266515, Blast_Score=198, Evalue=7e-51,
Organism=Homo sapiens, GI295293167, Length=426, Percent_Identity=31.2206572769953, Blast_Score=168, Evalue=8e-42,
Organism=Homo sapiens, GI295293178, Length=439, Percent_Identity=31.2072892938497, Blast_Score=168, Evalue=9e-42,
Organism=Homo sapiens, GI295293175, Length=439, Percent_Identity=31.2072892938497, Blast_Score=168, Evalue=9e-42,
Organism=Homo sapiens, GI295293173, Length=439, Percent_Identity=31.2072892938497, Blast_Score=168, Evalue=9e-42,
Organism=Homo sapiens, GI10835169, Length=439, Percent_Identity=31.2072892938497, Blast_Score=168, Evalue=9e-42,
Organism=Homo sapiens, GI295293171, Length=439, Percent_Identity=31.2072892938497, Blast_Score=168, Evalue=9e-42,
Organism=Homo sapiens, GI295293169, Length=439, Percent_Identity=31.2072892938497, Blast_Score=168, Evalue=9e-42,
Organism=Escherichia coli, GI1788736, Length=412, Percent_Identity=99.7572815533981, Blast_Score=814, Evalue=0.0,
Organism=Caenorhabditis elegans, GI193210616, Length=432, Percent_Identity=30.3240740740741, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17569473, Length=372, Percent_Identity=31.989247311828, Blast_Score=181, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI71999499, Length=439, Percent_Identity=28.9293849658314, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71993856, Length=225, Percent_Identity=36.4444444444444, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6323062, Length=390, Percent_Identity=33.8461538461538, Blast_Score=189, Evalue=6e-49,
Organism=Saccharomyces cerevisiae, GI6324450, Length=415, Percent_Identity=30.1204819277108, Blast_Score=172, Evalue=7e-44,
Organism=Saccharomyces cerevisiae, GI6321841, Length=418, Percent_Identity=31.3397129186603, Blast_Score=158, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24648607, Length=430, Percent_Identity=30.9302325581395, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI281362176, Length=430, Percent_Identity=30.9302325581395, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI24648609, Length=430, Percent_Identity=30.9302325581395, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI45553443, Length=406, Percent_Identity=31.7733990147783, Blast_Score=203, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 44164; Mature: 44033

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNYRVESSSGRAARKTRLALMGPAFIAAIGYIDPGNFATNIQAGASFGYQLLWVVVWAN
CCCEECCCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
LMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
KLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGLLLFVAAAYIVELIFSQPNLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
QLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGSRQQRYSATKWDVA
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHH
IAMTIAGFVNLAMMATAAAAFHFSGHTGVADLDEAYLTLQPLLSHAAATVFGLSLVAAGL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSTVVGTLAGQVVMQGFIRFHIPLWVRRTVTMLPSFIVILMGLDPTRILVMSQVLLSFGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ALALVPLLIFTSDSKLMGDLVNSKRVKQTGWVIVVLVVALNIWLLVGTALGL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA