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The map label for this gene is aroC [H]

Identifier: 157161818

GI number: 157161818

Start: 2487959

End: 2489044

Strand: Reverse

Name: aroC [H]

Synonym: EcHS_A2481

Alternate gene names: 157161818

Gene position: 2489044-2487959 (Counterclockwise)

Preceding gene: 157161819

Following gene: 157161817

Centisome position: 53.6

GC content: 57.0

Gene sequence:

>1086_bases
ATGGCTGGAAACACAATTGGACAACTCTTTCGCGTAACCACCTTCGGCGAATCGCACGGGCTGGCGCTCGGCTGCATCGT
CGATGGTGTTCCGCCAGGCATTCCGCTGACGGAAGCGGACCTGCAACATGACCTCGACCGTCGTCGCCCTGGGACATCGC
GCTATACCACCCAGCGCCGCGAGCCGGATCAGGTCAAAATTCTCTCCGGTGTTTTTGAAGGCGTTACTACCGGCACCAGC
ATTGGCTTGTTGATCGAAAACACTGACCAGCGCTCTCAGGATTACAGTGCGATTAAGGACGTTTTCCGTCCAGGCCATGC
CGATTACACCTACGAACAAAAATACGGTCTGCGCGATTATCGCGGCGGTGGACGTTCTTCCGCCCGCGAAACCGCCATGC
GCGTGGCGGCAGGAGCTATTGCCAAAAAATATCTCGCCGAGAAATTTGGTATTGAAATCCGTGGCTGCCTGACCCAGATG
GGCGACATTCCGCTGGATATCAAAGACTGGTCGCAGGTCGAGCAAAATCCGTTTTTTTGCCCGGACCCCGACAAAATCGA
CGCGTTAGACGAGTTGATGCGTGCGCTGAAAAAAGAGGGCGACTCCATCGGCGCTAAAGTCACCGTTGTTGCCAGTGGCG
TTCCTGCCGGACTTGGCGAGCCGGTCTTTGACCGCCTGGATGCTGACATCGCCCATGCGCTGATGAGCATCAACGCGGTG
AAAGGCGTGGAAATTGGCGACGGCTTTGACGTGGTGGCGCTGCGCGGCAGCCAGAACCGCGACGAAATCACCAAAGACGG
TTTCCAGAGCAACCATGCGGGCGGCATTCTCGGCGGTATCAGCAGCGGGCAGCAAATCATTGCTCATATGGCGCTGAAAC
CGACCTCCAGTATCACCGTGCCGGGGCGTACCATTAACCGCTTTGGCGAAGAAGTTGAGATGATCACCAAAGGCCGTCAC
GATCCCTGTGTCGGGATCCGCGCCGTGCCGATCGCAGAAGCGATGCTGGCGATCGTATTAATGGATCACCTGTTACGGCA
GCGGGCGCAAAATGCCGATGTGAAGACTGATATTCCACGCTGGTAA

Upstream 100 bases:

>100_bases
GTGTTTATGCTCACCAAAGAGCAGCTTATTGCCGCACGAGAACATTTCGCGATTTATAAAGATTAAGTAAACACGCAAAC
ACAACAATAACGGAGCCGTG

Downstream 100 bases:

>100_bases
AAAATGAACAAAACCGCGATTGCGCTGCTGGCCCTGCTTGCCAGTAGCGCCAGCCTGGCAGCGACGCCGTGGCAAAAAAT
AACCCAACCTGTGCCGGGTA

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTS
IGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQM
GDIPLDIKDWSQVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGLGEPVFDRLDADIAHALMSINAV
KGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGILGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRH
DPCVGIRAVPIAEAMLAIVLMDHLLRQRAQNADVKTDIPRW

Sequences:

>Translated_361_residues
MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTS
IGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQM
GDIPLDIKDWSQVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGLGEPVFDRLDADIAHALMSINAV
KGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGILGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRH
DPCVGIRAVPIAEAMLAIVLMDHLLRQRAQNADVKTDIPRW
>Mature_360_residues
AGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTSI
GLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQMG
DIPLDIKDWSQVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGLGEPVFDRLDADIAHALMSINAVK
GVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGILGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRHD
PCVGIRAVPIAEAMLAIVLMDHLLRQRAQNADVKTDIPRW

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=361, Percent_Identity=100, Blast_Score=738, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321290, Length=368, Percent_Identity=45.6521739130435, Blast_Score=311, Evalue=7e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 39138; Mature: 39007

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRR
CCCCHHHHHHHHEECCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
EPDQVKILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDY
CCCHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCHHC
RGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQMGDIPLDIKDWSQVEQNPFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCC
PDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGLGEPVFDRLDADIAHALMSINAV
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGILGGISSGQQIIAHMALKPTSSITV
CCCEECCCCEEEEECCCCCHHHHHHCCCCCCCCCCEECCCCCHHHHHHHHHCCCCCCEEE
PGRTINRFGEEVEMITKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRQRAQNADVKTDIPR
CCHHHHHHHHHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
W
C
>Mature Secondary Structure 
AGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRR
CCCHHHHHHHHEECCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
EPDQVKILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDY
CCCHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCHHC
RGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQMGDIPLDIKDWSQVEQNPFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCC
PDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGLGEPVFDRLDADIAHALMSINAV
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGILGGISSGQQIIAHMALKPTSSITV
CCCEECCCCEEEEECCCCCHHHHHHCCCCCCCCCCEECCCCCHHHHHHHHHCCCCCCEEE
PGRTINRFGEEVEMITKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRQRAQNADVKTDIPR
CCHHHHHHHHHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
W
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA