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The map label for this gene is yfcH [H]

Identifier: 157161792

GI number: 157161792

Start: 2463279

End: 2464172

Strand: Direct

Name: yfcH [H]

Synonym: EcHS_A2454

Alternate gene names: 157161792

Gene position: 2463279-2464172 (Clockwise)

Preceding gene: 157161791

Following gene: 157161809

Centisome position: 53.05

GC content: 55.03

Gene sequence:

>894_bases
ATGAACATAGTGATCACCGGAGGGACGGGATTAATTGGTCGCCATTTGATTCCGCGTTTGCTGGAGCTGGGCCATCAAAT
TACGGTAGTGACGCGTAACCCGCAGAAAGCCAGTTCCGTTCTCGGCCCTCGGGTGACACTATGGCAAGGGCTTGCCGATC
AAAGCAACCTCAACAGCGTTGATGCGGTAATCAACCTGGCCGGAGAACCGATTGCTGATAAACGCTGGACTCACGAGCAA
AAAGAGCGTCTCTGCCAAAGCCGCTGGAATATCACGCAAAAACTGGTCGATTTGATTAATGCCAGCGACACGCCACCGTC
GGTACTCATTTCCGGCTCGGCAACGGGCTATTATGGTGACTTAGGTGAAGTGGTGGTTACCGAAGAGGAACCGCCGCATA
ACGAATTTACCCATAAACTCTGCGCCCGCTGGGAAGAAATTGCCTGCCGGGCGCAAAGTGACAAAACGCGAGTGTGCCTG
CTGCGTACCGGTGTAGTGCTGGCACCGGATGGCGGTATTCTCGGTAAAATGCTGCCGCCGTTTCGTCTTGGCCTGGGCGG
GCCGATTGGCTCTGGTCGGCAGTATCTGGCCTGGATTCATATTGATGATATGGTCAACGGTATTCTCTGGCTGCTGGATA
ACGAGCTGCGCGGGCCATTTAATATGGTTTCGCCCTACCCGGTACGCAATGAACAATTTGCCCATGCGCTCGGTCATGCG
CTGCATCGCCCGGCCATTTTGCGCGTCCCCGCGACCGCCATTCGACTGTTAATGGGCGAATCTTCAGTACTGGTATTAGG
TGGACAACGCGCGCTGCCTAAACGGCTGGAAGAAGCGGGTTTTGCGTTTCGCTGGTACGATTTAGAAGAGGCGCTGGCGG
ATGTCGTTCGCTGA

Upstream 100 bases:

>100_bases
ATGCTGAAGTGGAGATCGATAAACTGCACGCGCTGCGCTACGCCGATTCGGTATCCATGACCTTAAGCTGGCAGCGTTAA
TCGCCATATCGGGAGGCTGC

Downstream 100 bases:

>100_bases
TGTGGTTTACAGCAAACATCCGCCAGTTAACTCCCGGTGTTACAGGATTAGTGGCTTTGCGCGATAAGATCGTCTGGTGA
AAGTCGGGTCACCATCATAA

Product: NAD-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNIVITGGTGLIGRHLIPRLLELGHQITVVTRNPQKASSVLGPRVTLWQGLADQSNLNSVDAVINLAGEPIADKRWTHEQ
KERLCQSRWNITQKLVDLINASDTPPSVLISGSATGYYGDLGEVVVTEEEPPHNEFTHKLCARWEEIACRAQSDKTRVCL
LRTGVVLAPDGGILGKMLPPFRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLDNELRGPFNMVSPYPVRNEQFAHALGHA
LHRPAILRVPATAIRLLMGESSVLVLGGQRALPKRLEEAGFAFRWYDLEEALADVVR

Sequences:

>Translated_297_residues
MNIVITGGTGLIGRHLIPRLLELGHQITVVTRNPQKASSVLGPRVTLWQGLADQSNLNSVDAVINLAGEPIADKRWTHEQ
KERLCQSRWNITQKLVDLINASDTPPSVLISGSATGYYGDLGEVVVTEEEPPHNEFTHKLCARWEEIACRAQSDKTRVCL
LRTGVVLAPDGGILGKMLPPFRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLDNELRGPFNMVSPYPVRNEQFAHALGHA
LHRPAILRVPATAIRLLMGESSVLVLGGQRALPKRLEEAGFAFRWYDLEEALADVVR
>Mature_297_residues
MNIVITGGTGLIGRHLIPRLLELGHQITVVTRNPQKASSVLGPRVTLWQGLADQSNLNSVDAVINLAGEPIADKRWTHEQ
KERLCQSRWNITQKLVDLINASDTPPSVLISGSATGYYGDLGEVVVTEEEPPHNEFTHKLCARWEEIACRAQSDKTRVCL
LRTGVVLAPDGGILGKMLPPFRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLDNELRGPFNMVSPYPVRNEQFAHALGHA
LHRPAILRVPATAIRLLMGESSVLVLGGQRALPKRLEEAGFAFRWYDLEEALADVVR

Specific function: Unknown

COG id: COG1090

COG function: function code R; Predicted nucleoside-diphosphate sugar epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family. SDR39U1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI116812630, Length=301, Percent_Identity=36.5448504983389, Blast_Score=181, Evalue=1e-45,
Organism=Escherichia coli, GI1788642, Length=297, Percent_Identity=99.6632996632997, Blast_Score=603, Evalue=1e-174,
Organism=Drosophila melanogaster, GI28573846, Length=296, Percent_Identity=30.7432432432432, Blast_Score=165, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013549
- InterPro:   IPR001509
- InterPro:   IPR016040
- InterPro:   IPR010099 [H]

Pfam domain/function: PF08338 DUF1731; PF01370 Epimerase [H]

EC number: NA

Molecular weight: Translated: 32729; Mature: 32729

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVITGGTGLIGRHLIPRLLELGHQITVVTRNPQKASSVLGPRVTLWQGLADQSNLNSV
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCHHHHHCCCCCCCCCHH
DAVINLAGEPIADKRWTHEQKERLCQSRWNITQKLVDLINASDTPPSVLISGSATGYYGD
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
LGEVVVTEEEPPHNEFTHKLCARWEEIACRAQSDKTRVCLLRTGVVLAPDGGILGKMLPP
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCHHCCCCC
FRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLDNELRGPFNMVSPYPVRNEQFAHALGHA
HHCCCCCCCCCCCEEEEEEEHHHHHHHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
LHRPAILRVPATAIRLLMGESSVLVLGGQRALPKRLEEAGFAFRWYDLEEALADVVR
HCCCEEEECCHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCEEEEECHHHHHHHHCC
>Mature Secondary Structure
MNIVITGGTGLIGRHLIPRLLELGHQITVVTRNPQKASSVLGPRVTLWQGLADQSNLNSV
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCHHHHHCCCCCCCCCHH
DAVINLAGEPIADKRWTHEQKERLCQSRWNITQKLVDLINASDTPPSVLISGSATGYYGD
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
LGEVVVTEEEPPHNEFTHKLCARWEEIACRAQSDKTRVCLLRTGVVLAPDGGILGKMLPP
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCHHCCCCC
FRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLDNELRGPFNMVSPYPVRNEQFAHALGHA
HHCCCCCCCCCCCEEEEEEEHHHHHHHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
LHRPAILRVPATAIRLLMGESSVLVLGGQRALPKRLEEAGFAFRWYDLEEALADVVR
HCCCEEEECCHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCEEEEECHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]