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The map label for this gene is inaA

Identifier: 157161720

GI number: 157161720

Start: 2389804

End: 2390454

Strand: Reverse

Name: inaA

Synonym: EcHS_A2377

Alternate gene names: 157161720

Gene position: 2390454-2389804 (Counterclockwise)

Preceding gene: 157161722

Following gene: 157161716

Centisome position: 51.48

GC content: 49.46

Gene sequence:

>651_bases
ATGGCAGTTTCAGCAAAGTACGACGAATTTAATCACTGGTGGGCAACAGAGGGCGACTGGGTTGAAGAGCCTAACTATCG
CCGTAATGGTATGAGCGGGGTGCAATGCGTCGAGCGCAACGGCAAAAAGCTGTATGTAAAGCGCATGACGCATCATCTGT
TTCATTCCGTACGTTATCCGTTCGGCCGACCAACGATTGTCCGTGAGGTTGCGGTAATTAAAGAACTGGAACGGGCCGGT
GTCATCGTGCCGAAGATCGTTTTTGGTGAAGCGGTGAAAATTGAGGGTGAATGGCGAGCGTTGCTGGTGACTGAAGATAT
GGCGGGGTTCATCAGCATTGCTGACTGGTATGCCCAGCATGCAGTATCGCCTTATTCTGACGAAGTACGGCAAGCCATGT
TGAAAGCAGTGGCGCTGGCGTTTAAGAAAATGCATAGCATTAATCGTCAGCATGGCTGTTGTTATGTTCGCCATATCTAT
GTGAAAACAGAAGGTAATGCAGAAGCTGGTTTTCTTGACCTGGAGAAAAGTCGTCGCCGCTTGCGTCGCGATAAAGCGAT
TAATCATGACTTCCGCCAGCTGGAAAAATATCTGGAGCCAATCCCCAAAGCGGACTGGGAGCAGGTGAAAGCGTATTACT
ACGCCATGTAA

Upstream 100 bases:

>100_bases
GTGGCAAAAGAAATTCATTAATACGACACGTTTCATTAAGATTTTCCTCAGGTAACCACCTATAGTCATTGTCGTTAATA
AAAATGACAGGCGATAGGGT

Downstream 100 bases:

>100_bases
TCGTTGTAGGCCAGATAAGACGCATAAGCGTTGTATCTGGCACTACAACCAATTCACATCTCGATTTCAATATCGCCTTT
TGCCCGGCAACAACAGGGCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MAVSAKYDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKLYVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAG
VIVPKIVFGEAVKIEGEWRALLVTEDMAGFISIADWYAQHAVSPYSDEVRQAMLKAVALAFKKMHSINRQHGCCYVRHIY
VKTEGNAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM

Sequences:

>Translated_216_residues
MAVSAKYDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKLYVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAG
VIVPKIVFGEAVKIEGEWRALLVTEDMAGFISIADWYAQHAVSPYSDEVRQAMLKAVALAFKKMHSINRQHGCCYVRHIY
VKTEGNAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM
>Mature_215_residues
AVSAKYDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKLYVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAGV
IVPKIVFGEAVKIEGEWRALLVTEDMAGFISIADWYAQHAVSPYSDEVRQAMLKAVALAFKKMHSINRQHGCCYVRHIYV
KTEGNAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM

Specific function: May be an environmental sensor responsive to several stimuli, including internal pH, proton motive force, temperature, and possibly other unknown factors

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. KdkA/rfaP family

Homologues:

Organism=Escherichia coli, GI1788569, Length=216, Percent_Identity=100, Blast_Score=451, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): INAA_ECOLI (P27294)

Other databases:

- EMBL:   K02672
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   C64994
- RefSeq:   AP_002834.1
- RefSeq:   NP_416740.1
- ProteinModelPortal:   P27294
- IntAct:   P27294
- STRING:   P27294
- EnsemblBacteria:   EBESCT00000001899
- EnsemblBacteria:   EBESCT00000017109
- GeneID:   946731
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW2231
- KEGG:   eco:b2237
- EchoBASE:   EB1392
- EcoGene:   EG11422
- eggNOG:   NOG13306
- GeneTree:   EBGT00050000011292
- HOGENOM:   HBG639303
- OMA:   REARTST
- ProtClustDB:   PRK09902
- BioCyc:   EcoCyc:EG11422-MONOMER
- Genevestigator:   P27294
- GO:   GO:0016020
- InterPro:   IPR011009
- InterPro:   IPR010440

Pfam domain/function: PF06293 Kdo; SSF56112 Kinase_like

EC number: NA

Molecular weight: Translated: 25296; Mature: 25165

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSAKYDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKLYVKRMTHHLFHSVRYP
CCCCCCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHCCCEEHHHHHHHHHHHHHCCC
FGRPTIVREVAVIKELERAGVIVPKIVFGEAVKIEGEWRALLVTEDMAGFISIADWYAQH
CCCCHHHHHHHHHHHHHHCCCEECCEECCCEEEECCCEEEEEEECCHHHHHHHHHHHHHH
AVSPYSDEVRQAMLKAVALAFKKMHSINRQHGCCYVRHIYVKTEGNAEAGFLDLEKSRRR
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCEEEHHHHHHH
LRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM
HHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
AVSAKYDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKLYVKRMTHHLFHSVRYP
CCCCCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHCCCEEHHHHHHHHHHHHHCCC
FGRPTIVREVAVIKELERAGVIVPKIVFGEAVKIEGEWRALLVTEDMAGFISIADWYAQH
CCCCHHHHHHHHHHHHHHCCCEECCEECCCEEEECCCEEEEEEECCHHHHHHHHHHHHHH
AVSPYSDEVRQAMLKAVALAFKKMHSINRQHGCCYVRHIYVKTEGNAEAGFLDLEKSRRR
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCEEEHHHHHHH
LRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM
HHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6087316; 9205837; 9278503; 1537798