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The map label for this gene is mqo [H]

Identifier: 157161692

GI number: 157161692

Start: 2346089

End: 2347735

Strand: Reverse

Name: mqo [H]

Synonym: EcHS_A2349

Alternate gene names: 157161692

Gene position: 2347735-2346089 (Counterclockwise)

Preceding gene: 157161693

Following gene: 157161691

Centisome position: 50.56

GC content: 54.1

Gene sequence:

>1647_bases
ATGAAAAAAGTGACTGCCATGCTCTTCTCGATGGCCGTGGGGCTTAATGCCGTTTCGATGGCGGCAAAAGCGAAAGCGTC
CGAGGAGCAGGAAACTGATGTACTGTTGATTGGCGGCGGCATTATGAGCGCCACGTTGGGGACCTATTTACGCGAGCTGG
AGCCTGAATGGTCGATGACCATGGTGGAGCGCCTGGAGGGTGTCGCGCAGGAGAGTTCGAACGGCTGGAATAACGCCGGA
ACCGGGCATTCTGCACTGATGGAACTGAACTACACCCCGCAAAACGCCGATGGCAGCATCAGTATTGAAAAAGCAGTCGC
CATTAACGAAGCATTTCAGATTTCCCGCCAGTTCTGGGCGCACCAGGTTGAGCGCGGCGTGCTGCGTACTCCGCGTTCAT
TTATCAATACCGTTCCGCATATGAGCTTTGTCTGGGGCGAGGATAACGTTAATTTCCTGCGCGCCCGTTACGCCGCGTTG
CAACAAAGCTCGCTGTTTCGCGGTATGCGTTACTCTGAAGATCACGCGCAGATCAAAGAGTGGGCACCGTTAGTGATGGA
AGGGCGCGATCCGCAACAGAAAGTGGCAGCCACGCGTACGGAAATTGGTACCGATGTGAACTACGGCGAGATCACCCGCC
AGTTAATTGCTTCCTTGCAGAAGAAATCTAACTTCTCGCTGCAACTCAGCAGCGAAGTCCGCGCCCTAAAGCGTAATGAC
GATAACACCTGGACCGTTACCGTTGCCGATCTGAAAAATGGCACTGCACAGAACATTCGTGCCAAATTTGTCTTTATCGG
CGCGGGCGGTGCGGCGCTGAAGCTGTTACAGGAATCGGGGATTCCGGAAGCGAAAGACTACGCCGGTTTCCCGGTGGGCG
GACAGTTCCTTGTTTCGGAAAACCCGGACGTGGTTAATCACCATCTGGCGAAGGTTTACGGTAAAGCATCCGTTGGCGCA
CCACCGATGTCGGTTCCGCATATCGATACCCGCGTTCTGGACGGTAAACGCGTAGTGCTGTTTGGGCCATTTGCCACCTT
CTCAACCAAATTCCTCAAAAACGGTTCATTGTGGGATCTGATGAGTTCCACCACCACCTCTAACGTGATGCCGATGATGC
ACGTCGGGCTGGATAATTTCGATCTGGTGAAATATCTGGTGAGTCAGGTGATGTTGAGTGAAGAGGATCGTTTTGAAGCG
TTGAAAGAGTACTATCCGCAGGCGAAAAAAGAGGACTGGCGTTTGTGGCAAGCGGGGCAGCGCGTGCAGATTATCAAGCG
TGATGCCGAGAAAGGTGGCGTACTGCGTCTGGGTACTGAAGTCGTCAGTGACCAGCAAGGGACCATTGCCGCGCTCCTGG
GGGCATCGCCAGGGGCGTCAACCGCCGCGCCGATTATGTTGGATCTGCTGGAAAAAGTATTTGGCGATCGCGTTTCCAGC
CCGCAATGGCAGGCTATGTTGAAAGCGATCGTTCCGTCTTATGGACGCAAGCTGAACGGTGATGTAGCGGCAACAGAACG
CGAGTTGCAGTACACCAGCGAAGTGCTGGGGCTGAAATACGACAAGCCGCAGGCAGCAGATAGTACGCCGAAACCGCAGT
TGAAACCGAAACCCGTTCAAAAAGAAGTGGCGGATATTGCGTTGTAA

Upstream 100 bases:

>100_bases
AATTTATAAACATTATTTAAATGTTGTTACTTAAGTGTTACCGTTGATGCCGCGCAAATCTCACCTGCAATAAAGCGACT
AAAAGTAAGGCATTAACAAG

Downstream 100 bases:

>100_bases
TGATGTGCCACATCCGGCATGGTATGCCGGGGATGTGGCGTATGCTGATAAGACGCGCCAGCGTCTTATCAGGCAACCGG
CTCGGGCGTTAGATGTCGGA

Product: malate:quinone oxidoreductase

Products: NA

Alternate protein names: MQO; Malate dehydrogenase [quinone] [H]

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSATLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAG
TGHSALMELNYTPQNADGSISIEKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAAL
QQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIASLQKKSNFSLQLSSEVRALKRND
DNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLLQESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGA
PPMSVPHIDTRVLDGKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVMLSEEDRFEA
LKEYYPQAKKEDWRLWQAGQRVQIIKRDAEKGGVLRLGTEVVSDQQGTIAALLGASPGASTAAPIMLDLLEKVFGDRVSS
PQWQAMLKAIVPSYGRKLNGDVAATERELQYTSEVLGLKYDKPQAADSTPKPQLKPKPVQKEVADIAL

Sequences:

>Translated_548_residues
MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSATLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAG
TGHSALMELNYTPQNADGSISIEKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAAL
QQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIASLQKKSNFSLQLSSEVRALKRND
DNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLLQESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGA
PPMSVPHIDTRVLDGKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVMLSEEDRFEA
LKEYYPQAKKEDWRLWQAGQRVQIIKRDAEKGGVLRLGTEVVSDQQGTIAALLGASPGASTAAPIMLDLLEKVFGDRVSS
PQWQAMLKAIVPSYGRKLNGDVAATERELQYTSEVLGLKYDKPQAADSTPKPQLKPKPVQKEVADIAL
>Mature_548_residues
MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSATLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAG
TGHSALMELNYTPQNADGSISIEKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAAL
QQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIASLQKKSNFSLQLSSEVRALKRND
DNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLLQESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGA
PPMSVPHIDTRVLDGKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVMLSEEDRFEA
LKEYYPQAKKEDWRLWQAGQRVQIIKRDAEKGGVLRLGTEVVSDQQGTIAALLGASPGASTAAPIMLDLLEKVFGDRVSS
PQWQAMLKAIVPSYGRKLNGDVAATERELQYTSEVLGLKYDKPQAADSTPKPQLKPKPVQKEVADIAL

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0579

COG function: function code R; Predicted dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MQO family [H]

Homologues:

Organism=Escherichia coli, GI1788539, Length=548, Percent_Identity=99.2700729927007, Blast_Score=1121, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006231 [H]

Pfam domain/function: PF06039 Mqo [H]

EC number: =1.1.5.4 [H]

Molecular weight: Translated: 60275; Mature: 60275

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSATLGTYLRELEPEWSMT
CHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCHHHH
MVERLEGVAQESSNGWNNAGTGHSALMELNYTPQNADGSISIEKAVAINEAFQISRQFWA
HHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHH
HQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAALQQSSLFRGMRYSEDHAQIKE
HHHHHHHHCCCHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
WAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIASLQKKSNFSLQLSSEVRALKRND
CCCCEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCC
DNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLLQESGIPEAKDYAGFPVGGQFLVSE
CCEEEEEEEECCCCCCCCEEEEEEEEECCHHHHHHHHHCCCCCCHHCCCCCCCCEEEECC
NPDVVNHHLAKVYGKASVGAPPMSVPHIDTRVLDGKRVVLFGPFATFSTKFLKNGSLWDL
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCEEEEEECHHHHHHHHHCCCCHHHH
MSSTTTSNVMPMMHVGLDNFDLVKYLVSQVMLSEEDRFEALKEYYPQAKKEDWRLWQAGQ
HHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHCCC
RVQIIKRDAEKGGVLRLGTEVVSDQQGTIAALLGASPGASTAAPIMLDLLEKVFGDRVSS
EEEEHHHHCCCCCEEEECHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCC
PQWQAMLKAIVPSYGRKLNGDVAATERELQYTSEVLGLKYDKPQAADSTPKPQLKPKPVQ
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
KEVADIAL
HHHHHHCC
>Mature Secondary Structure
MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSATLGTYLRELEPEWSMT
CHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCHHHH
MVERLEGVAQESSNGWNNAGTGHSALMELNYTPQNADGSISIEKAVAINEAFQISRQFWA
HHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHHH
HQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAALQQSSLFRGMRYSEDHAQIKE
HHHHHHHHCCCHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
WAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIASLQKKSNFSLQLSSEVRALKRND
CCCCEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCC
DNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLLQESGIPEAKDYAGFPVGGQFLVSE
CCEEEEEEEECCCCCCCCEEEEEEEEECCHHHHHHHHHCCCCCCHHCCCCCCCCEEEECC
NPDVVNHHLAKVYGKASVGAPPMSVPHIDTRVLDGKRVVLFGPFATFSTKFLKNGSLWDL
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCEEEEEECHHHHHHHHHCCCCHHHH
MSSTTTSNVMPMMHVGLDNFDLVKYLVSQVMLSEEDRFEALKEYYPQAKKEDWRLWQAGQ
HHCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHCCC
RVQIIKRDAEKGGVLRLGTEVVSDQQGTIAALLGASPGASTAAPIMLDLLEKVFGDRVSS
EEEEHHHHCCCCCEEEECHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCC
PQWQAMLKAIVPSYGRKLNGDVAATERELQYTSEVLGLKYDKPQAADSTPKPQLKPKPVQ
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
KEVADIAL
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA