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The map label for this gene is yeiI [H]

Identifier: 157161642

GI number: 157161642

Start: 2293927

End: 2295015

Strand: Direct

Name: yeiI [H]

Synonym: EcHS_A2296

Alternate gene names: 157161642

Gene position: 2293927-2295015 (Clockwise)

Preceding gene: 157161641

Following gene: 157161645

Centisome position: 49.4

GC content: 51.97

Gene sequence:

>1089_bases
ATGAATAACCGGGAAAAGGAGATCCTTGCAATTTTACGGCGTAACCCGCTGATTCAGCAGAACGAAATTGCGGACATGCT
GCAAATCAGTCGTTCGCGCGTTGCGGCGCATATTATGGATTTAATGCGCAAAGGGCGGATTAAAGGCAAAGGTTACATTC
TCACCGAGCAGGAATACTGCGTAGTGGTGGGGACAATCAATATGGATATTCGCGGGATGGCGGATATCCGTTACCCGCAA
GCGGCTTCTCATCCCGGTACAATTCATTGCTCGGCGGGCGGCGTGGGACGCAACATCGCCCACAATCTGGCGCTGTTAGG
CCGTGACGTCCATTTGCTTTCAGTGATTGGCGATGACTTTTATGGCGAAATGCTCCTGGAAGAAACGCGCCGTGCCGGCG
TGAATGTCTCCGGCTGCGTTCGTTTGCATGGTCAAAGCACATCGACGTATCTGGCAATTGCCAATCGAGACGATCAAACC
GTGCTGGCGATTAACGATACCCATCTGCTGGAACAGTTGACACCGCAACTACTGAACGGGTCGCGCGATTTACTTCGTCA
TGCGGGCGTGGTACTGGCTGATTGCAACCTGACAGCCGAGGCGCTGGAATGGGTCTTTACCCTCGCTGATGAAATCCCGG
TGTTTGTCGATACCGTTTCAGAATTCAAAGCGGGCAAAATCAAACACTGGCTGGCGCATATTCACACCCTGAAACCCACT
TTACCGGAGCTGGAAATTTTATGGGGACAGGCGATCACCAGCGATGCTGACCGTAATGCCGCAGTGAATGCATTGCATCA
GCAAGGTGTTCAGCAACTGTTTGTTTATTTGCCCGATGAGTCAGTTTATTGCAGCGAAAAGGATGGAGAACAATTTTTGC
TGACCGCGCCAGCGCATACGACAGTAGACAGTTTTGGTGCTGACGATGGTTTTATGGCGGGCCTGGTATATAGCTTTCTT
GAAGGATACAGTTTCCGCGACAGCGCCCGTTTTGCGGTAGCCTGCGCGGCAATTTCGCGCGCCAGCGGCAGCTTAAACAA
CCCTACCCTGTCTGCCGATAACGCGCTTTCATTAGTGCCAATGGTGTAA

Upstream 100 bases:

>100_bases
ACGGCATTCCGCTGATCCTTGAAACCATCAACCCGGATATCTGGGCAGAAGAGATCGCCTGGCTGAAAGCGCAACAAACT
GAAAAAGCGGTAGCCTGAAG

Downstream 100 bases:

>100_bases
CAATGTTGCCGGATTCGACGCTTGACCGCATCTTATCCGGCTCATAAATTGCGCACTACGCTAAACCAATAAAGAATCCT
GCAATAGTAGCACTCATCAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MNNREKEILAILRRNPLIQQNEIADMLQISRSRVAAHIMDLMRKGRIKGKGYILTEQEYCVVVGTINMDIRGMADIRYPQ
AASHPGTIHCSAGGVGRNIAHNLALLGRDVHLLSVIGDDFYGEMLLEETRRAGVNVSGCVRLHGQSTSTYLAIANRDDQT
VLAINDTHLLEQLTPQLLNGSRDLLRHAGVVLADCNLTAEALEWVFTLADEIPVFVDTVSEFKAGKIKHWLAHIHTLKPT
LPELEILWGQAITSDADRNAAVNALHQQGVQQLFVYLPDESVYCSEKDGEQFLLTAPAHTTVDSFGADDGFMAGLVYSFL
EGYSFRDSARFAVACAAISRASGSLNNPTLSADNALSLVPMV

Sequences:

>Translated_362_residues
MNNREKEILAILRRNPLIQQNEIADMLQISRSRVAAHIMDLMRKGRIKGKGYILTEQEYCVVVGTINMDIRGMADIRYPQ
AASHPGTIHCSAGGVGRNIAHNLALLGRDVHLLSVIGDDFYGEMLLEETRRAGVNVSGCVRLHGQSTSTYLAIANRDDQT
VLAINDTHLLEQLTPQLLNGSRDLLRHAGVVLADCNLTAEALEWVFTLADEIPVFVDTVSEFKAGKIKHWLAHIHTLKPT
LPELEILWGQAITSDADRNAAVNALHQQGVQQLFVYLPDESVYCSEKDGEQFLLTAPAHTTVDSFGADDGFMAGLVYSFL
EGYSFRDSARFAVACAAISRASGSLNNPTLSADNALSLVPMV
>Mature_362_residues
MNNREKEILAILRRNPLIQQNEIADMLQISRSRVAAHIMDLMRKGRIKGKGYILTEQEYCVVVGTINMDIRGMADIRYPQ
AASHPGTIHCSAGGVGRNIAHNLALLGRDVHLLSVIGDDFYGEMLLEETRRAGVNVSGCVRLHGQSTSTYLAIANRDDQT
VLAINDTHLLEQLTPQLLNGSRDLLRHAGVVLADCNLTAEALEWVFTLADEIPVFVDTVSEFKAGKIKHWLAHIHTLKPT
LPELEILWGQAITSDADRNAAVNALHQQGVQQLFVYLPDESVYCSEKDGEQFLLTAPAHTTVDSFGADDGFMAGLVYSFL
EGYSFRDSARFAVACAAISRASGSLNNPTLSADNALSLVPMV

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788484, Length=362, Percent_Identity=99.4475138121547, Blast_Score=746, Evalue=0.0,
Organism=Escherichia coli, GI1788491, Length=307, Percent_Identity=39.413680781759, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1790193, Length=262, Percent_Identity=23.2824427480916, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87081971, Length=266, Percent_Identity=24.4360902255639, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24580669, Length=284, Percent_Identity=26.4084507042254, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: NA

Molecular weight: Translated: 39665; Mature: 39665

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNREKEILAILRRNPLIQQNEIADMLQISRSRVAAHIMDLMRKGRIKGKGYILTEQEYC
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEE
VVVGTINMDIRGMADIRYPQAASHPGTIHCSAGGVGRNIAHNLALLGRDVHLLSVIGDDF
EEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCHH
YGEMLLEETRRAGVNVSGCVRLHGQSTSTYLAIANRDDQTVLAINDTHLLEQLTPQLLNG
HHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEECCCCCEEEEECCHHHHHHHHHHHHCC
SRDLLRHAGVVLADCNLTAEALEWVFTLADEIPVFVDTVSEFKAGKIKHWLAHIHTLKPT
CHHHHHHCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCCC
LPELEILWGQAITSDADRNAAVNALHQQGVQQLFVYLPDESVYCSEKDGEQFLLTAPAHT
CCCHHHHHCHHHCCCCCCHHHHHHHHHHHHHEEEEECCCCCEEECCCCCCEEEEECCCCC
TVDSFGADDGFMAGLVYSFLEGYSFRDSARFAVACAAISRASGSLNNPTLSADNALSLVP
CHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEC
MV
CC
>Mature Secondary Structure
MNNREKEILAILRRNPLIQQNEIADMLQISRSRVAAHIMDLMRKGRIKGKGYILTEQEYC
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEE
VVVGTINMDIRGMADIRYPQAASHPGTIHCSAGGVGRNIAHNLALLGRDVHLLSVIGDDF
EEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCHH
YGEMLLEETRRAGVNVSGCVRLHGQSTSTYLAIANRDDQTVLAINDTHLLEQLTPQLLNG
HHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEEECCCCCEEEEECCHHHHHHHHHHHHCC
SRDLLRHAGVVLADCNLTAEALEWVFTLADEIPVFVDTVSEFKAGKIKHWLAHIHTLKPT
CHHHHHHCCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCCC
LPELEILWGQAITSDADRNAAVNALHQQGVQQLFVYLPDESVYCSEKDGEQFLLTAPAHT
CCCHHHHHCHHHCCCCCCHHHHHHHHHHHHHEEEEECCCCCEEECCCCCCEEEEECCCCC
TVDSFGADDGFMAGLVYSFLEGYSFRDSARFAVACAAISRASGSLNNPTLSADNALSLVP
CHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEC
MV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 2460435 [H]