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The map label for this gene is fliG

Identifier: 157161410

GI number: 157161410

Start: 2034620

End: 2035615

Strand: Direct

Name: fliG

Synonym: EcHS_A2039

Alternate gene names: 157161410

Gene position: 2034620-2035615 (Clockwise)

Preceding gene: 157161409

Following gene: 157161411

Centisome position: 43.82

GC content: 55.72

Gene sequence:

>996_bases
ATGAGTAACCTGACAGGCACCGATAAAAGCGTCATCCTGCTGATGACCATTGGCGAAGACCGGGCGGCAGAGGTGTTCAA
GCACCTCTCCCAGCGCGAAGTGCAAACCCTGAGCGCTGCAATGGCGAACGTCACGCAGATCTCCAACAAGCAGCTAACCG
ATGTGCTGGCGGAGTTTGAGCAAGAAGCTGAACAGTTTGCCGCACTGAATATCAACGCCAACGATTATCTGCGTTCGGTA
TTGGTCAAAGCTCTGGGTGAGGAACGTGCCGCCAGCCTGCTGGAAGATATTCTCGAAACTCGCGATACCGCCAGCGGTAT
TGAAACGCTCAACTTTATGGAGCCGCAGAGTGCCGCCGATCTGATTCGCGATGAGCATCCGCAAATTATCGCCACCATTC
TGGTGCATCTGAAGCGCGCCCAGGCCGCCGATATTCTGGCGTTGTTCGATGAACGTCTGCGCCACGACGTGATGTTGCGT
ATCGCCACCTTTGGCGGCGTGCAGCCAGCCGCGCTGGCGGAACTGACCGAAGTACTGAATGGCTTGCTCGACGGTCAGAA
TCTCAAGCGCAGCAAAATGGGCGGCGTGAGAACGGCAGCCGAAATTATCAACCTGATGAAAACTCAGCAGGAAGAAGCCG
TTATTACCGCCGTGCGTGAATTCGACGGCGAACTGGCGCAAAAAATTATCGACGAGATGTTCCTGTTCGAGAATCTGGTG
GATGTCGACGATCGCAGCATTCAGCGTCTGTTGCAGGAAGTGGATTCCGAATCGTTGCTGATCGCGCTGAAAGGGGCCGA
GCAGCCACTGCGCGAGAAATTCCTGCGCAATATGTCGCAACGTGCCGCCGATATTCTGCGCGACGATCTCGCCAACCGTG
GTCCGGTGCGTCTGTCGCAGGTGGAAAACGAACAGAAAGCGATTCTGCTGATTGTGCGCCGTCTTGCCGAAACCGGCGAG
ATGGTGATTGGCAGCGGCGAGGATACCTATGTCTGA

Upstream 100 bases:

>100_bases
CGTCTGGGGGCAGAAGTCATGAGCCAGCGTATCCGTGAAATGTCTGATAACGATCCGCGCGTGGTGGCGCTGGTCATTCG
CCAGTGGATAAATAACGATC

Downstream 100 bases:

>100_bases
TAATCTGCCGTGGAAAACCTGGATGCCGGACGATCTTGCGCCACCACCGGCAGAGTTTGTGCCAATAGTCGAGCCGGAAG
AAACCATCATTGAAGAGGCC

Product: flagellar motor switch protein G

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANVTQISNKQLTDVLAEFEQEAEQFAALNINANDYLRSV
LVKALGEERAASLLEDILETRDTASGIETLNFMEPQSAADLIRDEHPQIIATILVHLKRAQAADILALFDERLRHDVMLR
IATFGGVQPAALAELTEVLNGLLDGQNLKRSKMGGVRTAAEIINLMKTQQEEAVITAVREFDGELAQKIIDEMFLFENLV
DVDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLRNMSQRAADILRDDLANRGPVRLSQVENEQKAILLIVRRLAETGE
MVIGSGEDTYV

Sequences:

>Translated_331_residues
MSNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANVTQISNKQLTDVLAEFEQEAEQFAALNINANDYLRSV
LVKALGEERAASLLEDILETRDTASGIETLNFMEPQSAADLIRDEHPQIIATILVHLKRAQAADILALFDERLRHDVMLR
IATFGGVQPAALAELTEVLNGLLDGQNLKRSKMGGVRTAAEIINLMKTQQEEAVITAVREFDGELAQKIIDEMFLFENLV
DVDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLRNMSQRAADILRDDLANRGPVRLSQVENEQKAILLIVRRLAETGE
MVIGSGEDTYV
>Mature_330_residues
SNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANVTQISNKQLTDVLAEFEQEAEQFAALNINANDYLRSVL
VKALGEERAASLLEDILETRDTASGIETLNFMEPQSAADLIRDEHPQIIATILVHLKRAQAADILALFDERLRHDVMLRI
ATFGGVQPAALAELTEVLNGLLDGQNLKRSKMGGVRTAAEIINLMKTQQEEAVITAVREFDGELAQKIIDEMFLFENLVD
VDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLRNMSQRAADILRDDLANRGPVRLSQVENEQKAILLIVRRLAETGEM
VIGSGEDTYV

Specific function: FliG is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the mot

COG id: COG1536

COG function: function code N; Flagellar motor switch protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Bacterial flagellum basal body (By similarity)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FliG family

Homologues:

Organism=Escherichia coli, GI1788249, Length=331, Percent_Identity=100, Blast_Score=657, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): FLIG_ECO57 (P0ABZ3)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   F90963
- RefSeq:   NP_288400.1
- RefSeq:   NP_310705.1
- ProteinModelPortal:   P0ABZ3
- SMR:   P0ABZ3
- EnsemblBacteria:   EBESCT00000024797
- EnsemblBacteria:   EBESCT00000056660
- GeneID:   912982
- GeneID:   961939
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z3029
- KEGG:   ecs:ECs2678
- GeneTree:   EBGT00050000009332
- HOGENOM:   HBG368483
- OMA:   ESLKWMD
- ProtClustDB:   PRK05686
- BioCyc:   ECOL83334:ECS2678-MONOMER
- GO:   GO:0006935
- InterPro:   IPR000090
- InterPro:   IPR023087
- InterPro:   IPR011002
- Gene3D:   G3DSA:1.10.220.30
- PRINTS:   PR00954
- TIGRFAMs:   TIGR00207

Pfam domain/function: PF01706 FliG_C; SSF48029 FliG_like

EC number: NA

Molecular weight: Translated: 36777; Mature: 36645

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANVTQISNKQLTDVLAEFE
CCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEAEQFAALNINANDYLRSVLVKALGEERAASLLEDILETRDTASGIETLNFMEPQSAAD
HHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LIRDEHPQIIATILVHLKRAQAADILALFDERLRHDVMLRIATFGGVQPAALAELTEVLN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GLLDGQNLKRSKMGGVRTAAEIINLMKTQQEEAVITAVREFDGELAQKIIDEMFLFENLV
HHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLRNMSQRAADILRDDLANRGPVRLSQ
CCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VENEQKAILLIVRRLAETGEMVIGSGEDTYV
HCCHHHHHHHHHHHHHHCCCEEEECCCCCCC
>Mature Secondary Structure 
SNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANVTQISNKQLTDVLAEFE
CCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QEAEQFAALNINANDYLRSVLVKALGEERAASLLEDILETRDTASGIETLNFMEPQSAAD
HHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LIRDEHPQIIATILVHLKRAQAADILALFDERLRHDVMLRIATFGGVQPAALAELTEVLN
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GLLDGQNLKRSKMGGVRTAAEIINLMKTQQEEAVITAVREFDGELAQKIIDEMFLFENLV
HHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLRNMSQRAADILRDDLANRGPVRLSQ
CCCHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
VENEQKAILLIVRRLAETGEMVIGSGEDTYV
HCCHHHHHHHHHHHHHHCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796