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The map label for this gene is yeaD [H]

Identifier: 157161241

GI number: 157161241

Start: 1881806

End: 1882711

Strand: Direct

Name: yeaD [H]

Synonym: EcHS_A1865

Alternate gene names: 157161241

Gene position: 1881806-1882711 (Clockwise)

Preceding gene: 157161240

Following gene: 157161244

Centisome position: 40.53

GC content: 49.67

Gene sequence:

>906_bases
ATGAAGTTAAAGGACTGCGTCATGATTAAGAAAATTTTTGCCCTTCCGGTCATCGAACAAATCTCCCCTGTCCTCTCCCG
TCGTAAACTGGATGAACTGGACCTCATTGTGGTCGATCATCCCCAGGTAAAAGCCTCTTTTGCATTACAGGGCGCACACC
TTCTCTCGTGGAAACCTGCGGGTGAAGAAGAAGTTCTGTGGTTGAGCAACAACACACCGTTCAAAAATGGCGTCGCTATT
CGCGGTGGCGTACCGGTTTGCTGGCCGTGGTTTGGTCCGGCGGCACAACAAGGTCTGCCTGCGCACGGTTTTGCCCGCAA
CCTGCCGTGGACGCTGAAATCACATCATGAAGATGCTGATGGCGTAGCGCTGACTTTTGAATTGACGCAAAGCGAAGAGA
CGAAAAAATTCTGGCCGCACGACTTTACGCTGTTAGCGCATTTCCGCGTGGGTAAAACTTGTGAAATCGATCTTGAATCA
CATGGCGAATTTGAAACCACCTCTGCCCTGCATACCTACTTTAACGTGGGTGATATCGCTAAGGTAAGCGTCAGTGGGCT
GGGCGATCGCTTCATTGATAAAGTGAATGACGCGAAAGAAAATGTACTGACCGATGGTATTCAGACCTTCCCTGACCGTA
CCGATCGCGTGTATCTGAATCCACAAGATTGCAGCGTGATTAATGATGAAGCGCTGAATCGTATTATCGCCGTAGGCCAC
CAGCATCATCTGAACGTTGTCGGCTGGAACCCGGGACCGGCGCTTTCAATTAGCATGGGCGATATGCCGGATGATGGCTA
CAAAACATTTGTTTGTGTAGAAACGGCTTACGCTTCAGAAACGCAAAAAGTGACCAAAGAGAAACCTGCACATCTGGCGC
AATCCATTCGCGTTGCGAAACGTTAA

Upstream 100 bases:

>100_bases
ACAAAGTTCTGGACCTGATCGCTCACATCTCCAAATAAGTTGAGATGACACTGTGATCTAAAAAGAGCGACTTCGGTCGC
TCTTTTTTTTACCTGATAAA

Downstream 100 bases:

>100_bases
TTTACGTTAATGTTGTGTGCCGGGTGCGATGCATCCGGCACACAACATCACACCATATCCAGCGCAGTTTTTCCTTTTGG
TGCCGGATATGCCTTATCCA

Product: aldose 1-epimerase family protein

Products: NA

Alternate protein names: Putative D-hexose-6-phosphate mutarotase; Unknown protein from 2D-page spots T26/PR37 [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MKLKDCVMIKKIFALPVIEQISPVLSRRKLDELDLIVVDHPQVKASFALQGAHLLSWKPAGEEEVLWLSNNTPFKNGVAI
RGGVPVCWPWFGPAAQQGLPAHGFARNLPWTLKSHHEDADGVALTFELTQSEETKKFWPHDFTLLAHFRVGKTCEIDLES
HGEFETTSALHTYFNVGDIAKVSVSGLGDRFIDKVNDAKENVLTDGIQTFPDRTDRVYLNPQDCSVINDEALNRIIAVGH
QHHLNVVGWNPGPALSISMGDMPDDGYKTFVCVETAYASETQKVTKEKPAHLAQSIRVAKR

Sequences:

>Translated_301_residues
MKLKDCVMIKKIFALPVIEQISPVLSRRKLDELDLIVVDHPQVKASFALQGAHLLSWKPAGEEEVLWLSNNTPFKNGVAI
RGGVPVCWPWFGPAAQQGLPAHGFARNLPWTLKSHHEDADGVALTFELTQSEETKKFWPHDFTLLAHFRVGKTCEIDLES
HGEFETTSALHTYFNVGDIAKVSVSGLGDRFIDKVNDAKENVLTDGIQTFPDRTDRVYLNPQDCSVINDEALNRIIAVGH
QHHLNVVGWNPGPALSISMGDMPDDGYKTFVCVETAYASETQKVTKEKPAHLAQSIRVAKR
>Mature_301_residues
MKLKDCVMIKKIFALPVIEQISPVLSRRKLDELDLIVVDHPQVKASFALQGAHLLSWKPAGEEEVLWLSNNTPFKNGVAI
RGGVPVCWPWFGPAAQQGLPAHGFARNLPWTLKSHHEDADGVALTFELTQSEETKKFWPHDFTLLAHFRVGKTCEIDLES
HGEFETTSALHTYFNVGDIAKVSVSGLGDRFIDKVNDAKENVLTDGIQTFPDRTDRVYLNPQDCSVINDEALNRIIAVGH
QHHLNVVGWNPGPALSISMGDMPDDGYKTFVCVETAYASETQKVTKEKPAHLAQSIRVAKR

Specific function: Unknown

COG id: COG0676

COG function: function code G; Uncharacterized enzymes related to aldose 1-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glucose-6-phosphate 1-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI87081973, Length=294, Percent_Identity=100, Blast_Score=611, Evalue=1e-176,
Organism=Saccharomyces cerevisiae, GI6323746, Length=265, Percent_Identity=30.9433962264151, Blast_Score=89, Evalue=8e-19,
Organism=Drosophila melanogaster, GI19921284, Length=250, Percent_Identity=29.6, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008183
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.15 [H]

Molecular weight: Translated: 33484; Mature: 33484

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKDCVMIKKIFALPVIEQISPVLSRRKLDELDLIVVDHPQVKASFALQGAHLLSWKPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEECCCEEEEECCC
GEEEVLWLSNNTPFKNGVAIRGGVPVCWPWFGPAAQQGLPAHGFARNLPWTLKSHHEDAD
CCCEEEEEECCCCCCCCEEEECCCCEEECCCCCHHHCCCCCCCHHCCCCCCCCCCCCCCC
GVALTFELTQSEETKKFWPHDFTLLAHFRVGKTCEIDLESHGEFETTSALHTYFNVGDIA
CEEEEEEECCCCCCHHCCCCCEEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHCCCCEE
KVSVSGLGDRFIDKVNDAKENVLTDGIQTFPDRTDRVYLNPQDCSVINDEALNRIIAVGH
EEEHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEECHHHHHHHHHCCC
QHHLNVVGWNPGPALSISMGDMPDDGYKTFVCVETAYASETQKVTKEKPAHLAQSIRVAK
CCEEEEEEECCCCEEEEECCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHC
R
C
>Mature Secondary Structure
MKLKDCVMIKKIFALPVIEQISPVLSRRKLDELDLIVVDHPQVKASFALQGAHLLSWKPA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEECCCEEEEECCC
GEEEVLWLSNNTPFKNGVAIRGGVPVCWPWFGPAAQQGLPAHGFARNLPWTLKSHHEDAD
CCCEEEEEECCCCCCCCEEEECCCCEEECCCCCHHHCCCCCCCHHCCCCCCCCCCCCCCC
GVALTFELTQSEETKKFWPHDFTLLAHFRVGKTCEIDLESHGEFETTSALHTYFNVGDIA
CEEEEEEECCCCCCHHCCCCCEEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHCCCCEE
KVSVSGLGDRFIDKVNDAKENVLTDGIQTFPDRTDRVYLNPQDCSVINDEALNRIIAVGH
EEEHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEECHHHHHHHHHCCC
QHHLNVVGWNPGPALSISMGDMPDDGYKTFVCVETAYASETQKVTKEKPAHLAQSIRVAK
CCEEEEEEECCCCEEEEECCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9298646; 10493123 [H]