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The map label for this gene is ydiO

Identifier: 157161159

GI number: 157161159

Start: 1799221

End: 1800372

Strand: Direct

Name: ydiO

Synonym: EcHS_A1777

Alternate gene names: 157161159

Gene position: 1799221-1800372 (Clockwise)

Preceding gene: 157161158

Following gene: 157161164

Centisome position: 38.75

GC content: 51.74

Gene sequence:

>1152_bases
ATGGATTTTTCTTTAACTGAAGAACAAGAACTGCTGCTGGCCAGTATTCGCGAACTGATTACGACTAACTTTCCGGAAGA
GTATTTCCGCACCTGCGATCAAAACGGGACATATCCGCGTGAGTTTATGCGGGCGCTGGCGGATAACGGTATTTCCATGC
TTGGCGTGCCGGAAGAATTTGGTGGTATCCCTGCGGATTACGTCACCCAAATGCTGGCGCTGATGGAAGTGTCAAAATGC
GGTGCTCCGGCATTTTTAATTACCAACGGTCAATGTATTCACAGTATGCGCCGTTTCGGTTCTGCAGAGCAGCTACGTAA
AACGGCAGAAAGCACCCTGGAAACCGGCGACCCCGCCTATGCCCTGGCGTTGACGGAACCAGGTGCTGGCTCAGATAACA
ACAGTGCCACCACCACTTACACGCGTAAAAACGGCAAGGTTTACATCAACGGACAGAAAACCTTTATTACCGGTGCGAAA
GAGTACCCGTATATGCTGGTGTTGGCGCGCGATCCGCAACCGAAAGATCCCAAAAAAGCCTTCACCCTGTGGTGGGTCGA
CTCCAGTAAGCCCGGCATTAAGATTAACCCGCTGCATAAAATCGGCTGGCATATGCTCAGCACCTGCGAAGTCTATCTCG
ACAACGTGGAAGTTGAAGAGAGCGACATGGTGGGCGAAGAAGGAATGGGTTTCCTCAATGTGATGTACAACTTTGAGATG
GAGCGCCTGATCAACGCCGCGCGCAGCACCGGCTTTGCCGAATGCGCCTTTGAAGATGCCGCCCGCTATGCCAACCAACG
TATCGCTTTTGGTAAGCCCATTGGTCATAACCAGATGATCCAGGAAAAACTGGCGCTGATGGCGATTAAGATTGACAACA
TGCGCAACATGGTGCTGAAAGTGGCATGGCAAGCCGATCAGCATCAGTCACTGCGCACCAGCGCGGCGCTGGCAAAACTG
TATTGCGCACGTACCGCAATGGAAGTCATTGATGATGCGATTCAAATCATGGGCGGTCTGGGCTATACCGATGAAGCGCG
CGTCTCCCGCTTCTGGCGTGATGTCCGTTGTGAACGTATCGGCGGCGGTACAGACGAAATTATGATTTACGTAGCAGGTC
GGCAGATCCTGAAAGACTATCAGAACAAATAA

Upstream 100 bases:

>100_bases
GTGATTTCGCCAGAACTCAAACTGATGGACGAAAGATTATTTATCGATGCGGCGATGGGTTTTGTCCTGCCTGAAGCGGC
TCATTAACAGGAGTATAATG

Downstream 100 bases:

>100_bases
TCTGCAGGCGGCGCAGCTTCTTAACAAACTGCGCCGCCAGATTTATCCAACAAGACTTACCGGTTGAGGAAATTCAGATA
GGATTTCTTGTTCCGCAAAA

Product: putative acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MDFSLTEEQELLLASIRELITTNFPEEYFRTCDQNGTYPREFMRALADNGISMLGVPEEFGGIPADYVTQMLALMEVSKC
GAPAFLITNGQCIHSMRRFGSAEQLRKTAESTLETGDPAYALALTEPGAGSDNNSATTTYTRKNGKVYINGQKTFITGAK
EYPYMLVLARDPQPKDPKKAFTLWWVDSSKPGIKINPLHKIGWHMLSTCEVYLDNVEVEESDMVGEEGMGFLNVMYNFEM
ERLINAARSTGFAECAFEDAARYANQRIAFGKPIGHNQMIQEKLALMAIKIDNMRNMVLKVAWQADQHQSLRTSAALAKL
YCARTAMEVIDDAIQIMGGLGYTDEARVSRFWRDVRCERIGGGTDEIMIYVAGRQILKDYQNK

Sequences:

>Translated_383_residues
MDFSLTEEQELLLASIRELITTNFPEEYFRTCDQNGTYPREFMRALADNGISMLGVPEEFGGIPADYVTQMLALMEVSKC
GAPAFLITNGQCIHSMRRFGSAEQLRKTAESTLETGDPAYALALTEPGAGSDNNSATTTYTRKNGKVYINGQKTFITGAK
EYPYMLVLARDPQPKDPKKAFTLWWVDSSKPGIKINPLHKIGWHMLSTCEVYLDNVEVEESDMVGEEGMGFLNVMYNFEM
ERLINAARSTGFAECAFEDAARYANQRIAFGKPIGHNQMIQEKLALMAIKIDNMRNMVLKVAWQADQHQSLRTSAALAKL
YCARTAMEVIDDAIQIMGGLGYTDEARVSRFWRDVRCERIGGGTDEIMIYVAGRQILKDYQNK
>Mature_383_residues
MDFSLTEEQELLLASIRELITTNFPEEYFRTCDQNGTYPREFMRALADNGISMLGVPEEFGGIPADYVTQMLALMEVSKC
GAPAFLITNGQCIHSMRRFGSAEQLRKTAESTLETGDPAYALALTEPGAGSDNNSATTTYTRKNGKVYINGQKTFITGAK
EYPYMLVLARDPQPKDPKKAFTLWWVDSSKPGIKINPLHKIGWHMLSTCEVYLDNVEVEESDMVGEEGMGFLNVMYNFEM
ERLINAARSTGFAECAFEDAARYANQRIAFGKPIGHNQMIQEKLALMAIKIDNMRNMVLKVAWQADQHQSLRTSAALAKL
YCARTAMEVIDDAIQIMGGLGYTDEARVSRFWRDVRCERIGGGTDEIMIYVAGRQILKDYQNK

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family

Homologues:

Organism=Homo sapiens, GI4557233, Length=383, Percent_Identity=30.5483028720627, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI4501857, Length=382, Percent_Identity=28.7958115183246, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI226958412, Length=384, Percent_Identity=28.3854166666667, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI226958414, Length=347, Percent_Identity=29.3948126801153, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI187960098, Length=389, Percent_Identity=29.8200514138817, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI4557231, Length=389, Percent_Identity=29.8200514138817, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI4501859, Length=381, Percent_Identity=27.0341207349081, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI7656849, Length=355, Percent_Identity=28.169014084507, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI21361497, Length=366, Percent_Identity=31.4207650273224, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI76496475, Length=386, Percent_Identity=31.3471502590674, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI4557235, Length=386, Percent_Identity=31.3471502590674, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI38505218, Length=314, Percent_Identity=26.7515923566879, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI48976061, Length=302, Percent_Identity=27.8145695364238, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI211971008, Length=302, Percent_Identity=27.8145695364238, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI4503943, Length=301, Percent_Identity=27.5747508305648, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI7669494, Length=276, Percent_Identity=27.8985507246377, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI87081958, Length=383, Percent_Identity=100, Blast_Score=804, Evalue=0.0,
Organism=Escherichia coli, GI1786223, Length=382, Percent_Identity=47.9057591623037, Blast_Score=367, Evalue=1e-102,
Organism=Escherichia coli, GI87082384, Length=258, Percent_Identity=26.3565891472868, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=385, Percent_Identity=32.7272727272727, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17569725, Length=355, Percent_Identity=31.830985915493, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17570075, Length=388, Percent_Identity=30.1546391752577, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17534899, Length=352, Percent_Identity=29.8295454545455, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17505929, Length=345, Percent_Identity=29.8550724637681, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17551932, Length=381, Percent_Identity=28.0839895013123, Blast_Score=144, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI17508101, Length=383, Percent_Identity=25.8485639686684, Blast_Score=138, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17506239, Length=384, Percent_Identity=26.3020833333333, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17533517, Length=352, Percent_Identity=26.9886363636364, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71985184, Length=352, Percent_Identity=28.125, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71990804, Length=280, Percent_Identity=27.8571428571429, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17534353, Length=289, Percent_Identity=27.3356401384083, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71982178, Length=275, Percent_Identity=25.0909090909091, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562446, Length=304, Percent_Identity=26.6447368421053, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71985192, Length=299, Percent_Identity=26.7558528428094, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17531909, Length=247, Percent_Identity=25.1012145748988, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356377, Length=382, Percent_Identity=32.4607329842932, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24646207, Length=380, Percent_Identity=31.3157894736842, Blast_Score=174, Evalue=6e-44,
Organism=Drosophila melanogaster, GI21355753, Length=347, Percent_Identity=31.1239193083574, Blast_Score=154, Evalue=7e-38,
Organism=Drosophila melanogaster, GI24660351, Length=385, Percent_Identity=31.9480519480519, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24666513, Length=380, Percent_Identity=27.8947368421053, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI281363737, Length=342, Percent_Identity=30.9941520467836, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI19920834, Length=281, Percent_Identity=28.1138790035587, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YDIO_ECO57 (P0A9V0)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- RefSeq:   NP_288129.2
- RefSeq:   NP_310429.2
- ProteinModelPortal:   P0A9V0
- SMR:   P0A9V0
- EnsemblBacteria:   EBESCT00000027813
- EnsemblBacteria:   EBESCT00000056876
- GeneID:   914999
- GeneID:   961666
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z2723
- KEGG:   ecs:ECs2402
- GeneTree:   EBGT00050000008857
- HOGENOM:   HBG699365
- OMA:   CLARNSE
- ProtClustDB:   PRK12341
- BioCyc:   ECOL83334:ECS2402-MONOMER
- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100
- Gene3D:   G3DSA:2.40.110.10
- Gene3D:   G3DSA:1.10.540.10
- Gene3D:   G3DSA:1.20.140.10

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N; SSF56645 AcylCoA_dehyd_NM; SSF47203 AcylCoADH_C_like

EC number: NA

Molecular weight: Translated: 43003; Mature: 43003

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00072 ACYL_COA_DH_1; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSLTEEQELLLASIRELITTNFPEEYFRTCDQNGTYPREFMRALADNGISMLGVPEEF
CCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCEEEECCHHH
GGIPADYVTQMLALMEVSKCGAPAFLITNGQCIHSMRRFGSAEQLRKTAESTLETGDPAY
CCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCHHHHHHHHHHHHCCCCCEE
ALALTEPGAGSDNNSATTTYTRKNGKVYINGQKTFITGAKEYPYMLVLARDPQPKDPKKA
EEEEECCCCCCCCCCCEEEEEECCCEEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCE
FTLWWVDSSKPGIKINPLHKIGWHMLSTCEVYLDNVEVEESDMVGEEGMGFLNVMYNFEM
EEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHH
ERLINAARSTGFAECAFEDAARYANQRIAFGKPIGHNQMIQEKLALMAIKIDNMRNMVLK
HHHHHHHHCCCCHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VAWQADQHQSLRTSAALAKLYCARTAMEVIDDAIQIMGGLGYTDEARVSRFWRDVRCERI
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
GGGTDEIMIYVAGRQILKDYQNK
CCCCCEEEEEECCHHHHHHHCCC
>Mature Secondary Structure
MDFSLTEEQELLLASIRELITTNFPEEYFRTCDQNGTYPREFMRALADNGISMLGVPEEF
CCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCEEEECCHHH
GGIPADYVTQMLALMEVSKCGAPAFLITNGQCIHSMRRFGSAEQLRKTAESTLETGDPAY
CCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHCCCHHHHHHHHHHHHCCCCCEE
ALALTEPGAGSDNNSATTTYTRKNGKVYINGQKTFITGAKEYPYMLVLARDPQPKDPKKA
EEEEECCCCCCCCCCCEEEEEECCCEEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCE
FTLWWVDSSKPGIKINPLHKIGWHMLSTCEVYLDNVEVEESDMVGEEGMGFLNVMYNFEM
EEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHH
ERLINAARSTGFAECAFEDAARYANQRIAFGKPIGHNQMIQEKLALMAIKIDNMRNMVLK
HHHHHHHHCCCCHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VAWQADQHQSLRTSAALAKLYCARTAMEVIDDAIQIMGGLGYTDEARVSRFWRDVRCERI
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
GGGTDEIMIYVAGRQILKDYQNK
CCCCCEEEEEECCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796