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The map label for this gene is ydhJ

Identifier: 157161107

GI number: 157161107

Start: 1743217

End: 1744074

Strand: Direct

Name: ydhJ

Synonym: EcHS_A1721

Alternate gene names: 157161107

Gene position: 1743217-1744074 (Clockwise)

Preceding gene: 157161106

Following gene: 157161108

Centisome position: 37.54

GC content: 50.23

Gene sequence:

>858_bases
ATGTCAATTAAAACAATTAAGTATTTCTCAACAATCATTGTAGCGGTAGTTGCGGTTCTTGCCGGATGGTGGCTGTGGAA
TTATTACATGCAATCTCCGTGGACACGCGACGGGAAAATACGCGCAGAACAGGTTTCTATCACCCCACAGGTGTCGGGAC
GTATTGTTGAGCTGAATATAAAAGACAACCAGCTGGTTAACGCGGGGGATCTTCTGCTCACGATCGATAAAACGCCCTTT
CAGATCGCCGAGCTGAACGCACAGGCTCAGCTGGCGAAAGCGCAATCTGACCTCGCAAAAGCCAATAACGAAGCGAATCG
TCGTCGTCATCTCTCACAAAATTTTATTTCTGCCGAAGAACTCGATACCGCTAACCTCAATGTTAAAGCGATGCAGGCCA
GTGTTGATGCCGCACAGGCGACGCTGAAACAGGCACAATGGCAACTGGCGCAAACGGAAATTCGCGCCCCGGTGAGTGGA
TGGGTGACTAACCTTACTACCCGCATCGGCGATTACGCTGATACCGGGAAACCGCTGTTTGCCCTTGTCGACAGCCACTC
GTTTTACGTCATTGGTTATTTTGAAGAAACCAAGTTGCGCCATATCCGCGAAGGTGCACCAGCACAAATTACCCTCTATA
GTGATAACAAAACGTTACAGGGTCACGTTTCCAGTATCGGTCGGGCGATTTATGATCAGAGCGTTGAAAGTGACTCAAGC
CTTATTCCGGATGTTAAACCTAACGTCCCCTGGGTTCGACTCGCCCAACGCGTTCCCGTCCGCTTTGCGCTGGATAAAGT
CCCAGGCGATGTCACGTTGGTGTCGGGCACCACCTGTAGCATTGCCGTAGGTCAATAA

Upstream 100 bases:

>100_bases
GGATCTACGCCGGTGACATCTGGCATCCCTTGTTAATGGATTTATCGCTGTTTGCGATTTGCGTTTGCCTTGCTCTGGCA
ATACTGATTGCGTGGTAACT

Downstream 100 bases:

>100_bases
TGAACGCATCGTCATGGTCCTTGCGCAATTTGCCCTGGTTCAGGGCCACGCTGGCGCAATGGCGTTATGCGTTACGCAAT
ACCATTGCCATGTGTCTGGC

Product: MFP family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MSIKTIKYFSTIIVAVVAVLAGWWLWNYYMQSPWTRDGKIRAEQVSITPQVSGRIVELNIKDNQLVNAGDLLLTIDKTPF
QIAELNAQAQLAKAQSDLAKANNEANRRRHLSQNFISAEELDTANLNVKAMQASVDAAQATLKQAQWQLAQTEIRAPVSG
WVTNLTTRIGDYADTGKPLFALVDSHSFYVIGYFEETKLRHIREGAPAQITLYSDNKTLQGHVSSIGRAIYDQSVESDSS
LIPDVKPNVPWVRLAQRVPVRFALDKVPGDVTLVSGTTCSIAVGQ

Sequences:

>Translated_285_residues
MSIKTIKYFSTIIVAVVAVLAGWWLWNYYMQSPWTRDGKIRAEQVSITPQVSGRIVELNIKDNQLVNAGDLLLTIDKTPF
QIAELNAQAQLAKAQSDLAKANNEANRRRHLSQNFISAEELDTANLNVKAMQASVDAAQATLKQAQWQLAQTEIRAPVSG
WVTNLTTRIGDYADTGKPLFALVDSHSFYVIGYFEETKLRHIREGAPAQITLYSDNKTLQGHVSSIGRAIYDQSVESDSS
LIPDVKPNVPWVRLAQRVPVRFALDKVPGDVTLVSGTTCSIAVGQ
>Mature_284_residues
SIKTIKYFSTIIVAVVAVLAGWWLWNYYMQSPWTRDGKIRAEQVSITPQVSGRIVELNIKDNQLVNAGDLLLTIDKTPFQ
IAELNAQAQLAKAQSDLAKANNEANRRRHLSQNFISAEELDTANLNVKAMQASVDAAQATLKQAQWQLAQTEIRAPVSGW
VTNLTTRIGDYADTGKPLFALVDSHSFYVIGYFEETKLRHIREGAPAQITLYSDNKTLQGHVSSIGRAIYDQSVESDSSL
IPDVKPNVPWVRLAQRVPVRFALDKVPGDVTLVSGTTCSIAVGQ

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family

Homologues:

Organism=Escherichia coli, GI87081951, Length=285, Percent_Identity=100, Blast_Score=584, Evalue=1e-168,
Organism=Escherichia coli, GI1789637, Length=282, Percent_Identity=40.7801418439716, Blast_Score=201, Evalue=3e-53,
Organism=Escherichia coli, GI1790519, Length=293, Percent_Identity=33.4470989761092, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1788711, Length=311, Percent_Identity=27.9742765273312, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1789041, Length=304, Percent_Identity=27.6315789473684, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87082036, Length=161, Percent_Identity=30.4347826086957, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790012, Length=269, Percent_Identity=23.7918215613383, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790024, Length=254, Percent_Identity=24.4094488188976, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789929, Length=130, Percent_Identity=35.3846153846154, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YDHJ_ECOLI (P76185)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   F64921
- RefSeq:   AP_002266.1
- RefSeq:   NP_416161.4
- ProteinModelPortal:   P76185
- SMR:   P76185
- DIP:   DIP-11733N
- STRING:   P76185
- EnsemblBacteria:   EBESCT00000004207
- EnsemblBacteria:   EBESCT00000015049
- GeneID:   946499
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW1636
- KEGG:   eco:b1644
- EchoBASE:   EB3702
- EcoGene:   EG13944
- eggNOG:   COG1566
- GeneTree:   EBGT00070000031781
- HOGENOM:   HBG624965
- OMA:   HASSIGR
- ProtClustDB:   CLSK880153
- BioCyc:   EcoCyc:G6884-MONOMER
- Genevestigator:   P76185
- InterPro:   IPR006143

Pfam domain/function: PF00529 HlyD

EC number: NA

Molecular weight: Translated: 31496; Mature: 31365

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x14d17750)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKTIKYFSTIIVAVVAVLAGWWLWNYYMQSPWTRDGKIRAEQVSITPQVSGRIVELNI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEEEEE
KDNQLVNAGDLLLTIDKTPFQIAELNAQAQLAKAQSDLAKANNEANRRRHLSQNFISAEE
CCCCEECCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHH
LDTANLNVKAMQASVDAAQATLKQAQWQLAQTEIRAPVSGWVTNLTTRIGDYADTGKPLF
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEE
ALVDSHSFYVIGYFEETKLRHIREGAPAQITLYSDNKTLQGHVSSIGRAIYDQSVESDSS
EEEECCCEEEEEEECHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCC
LIPDVKPNVPWVRLAQRVPVRFALDKVPGDVTLVSGTTCSIAVGQ
CCCCCCCCCCHHHHHHHCCEEEEEECCCCCEEEEECCEEEEEECH
>Mature Secondary Structure 
SIKTIKYFSTIIVAVVAVLAGWWLWNYYMQSPWTRDGKIRAEQVSITPQVSGRIVELNI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEEEEE
KDNQLVNAGDLLLTIDKTPFQIAELNAQAQLAKAQSDLAKANNEANRRRHLSQNFISAEE
CCCCEECCCCEEEEECCCCCEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHH
LDTANLNVKAMQASVDAAQATLKQAQWQLAQTEIRAPVSGWVTNLTTRIGDYADTGKPLF
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEE
ALVDSHSFYVIGYFEETKLRHIREGAPAQITLYSDNKTLQGHVSSIGRAIYDQSVESDSS
EEEECCCEEEEEEECHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCC
LIPDVKPNVPWVRLAQRVPVRFALDKVPGDVTLVSGTTCSIAVGQ
CCCCCCCCCCHHHHHHHCCEEEEEECCCCCEEEEECCEEEEEECH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503