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The map label for this gene is lsrC [H]

Identifier: 157160986

GI number: 157160986

Start: 1619841

End: 1620869

Strand: Direct

Name: lsrC [H]

Synonym: EcHS_A1596

Alternate gene names: 157160986

Gene position: 1619841-1620869 (Clockwise)

Preceding gene: 157160985

Following gene: 157160987

Centisome position: 34.88

GC content: 54.23

Gene sequence:

>1029_bases
ATGCTGAAGTTTATTCAGAACAACCGTGAAATCACGGCACTGCTGGCGGTGGTGCTGCTGTTTGTATTACCCGGTTTTCT
CGACCGCCAGTATTTAAGTGTGCAAACGCTGACCATGGTTTATAGCAGCGCGCAAATCCTGATCCTGCTGGCAATGGGCG
CGACGCTGGTAATGCTTACGCGCAATATTGATGTTTCAGTGGGTTCGATTACCGGAATGTGCGCGGTGCTGTTGGGGATG
TTACTGAACGCAGGATATTCACTACCTGTTGCCTGTGTCACGACTTTACTGCTTGGTTTGCTCGCGGGATTTTTCAACGG
TGTCCTGGTCGCGTGGCTAAAGATTCCTGCCATTGTTGCCACCCTTGGCACGTTAGGGTTGTACAGAGGCATCATGTTGC
TGTGGACTGGCGGTAAATGGATTGAAGGGTTACCCGCCGAACTGAAACAGCTCTCCGCACCGCTGCTGTTTGGCGTTTCC
GCGATTGGTTGGTTGACGATAATTCTGGTGGCATTTATGGCCTGGCTGCTGGCGAAGACGGCGTTTGGACGCAGTTTTTA
TGCCACGGGCGATAATTTACAGGGCGCTCGTCAACTGGGCGTTCGTACGGAAGCCATTCGCATTGTGGCATTTTCGTTGA
ACGGCTGCATGGCGGCACTGGCGGGAATTGTGTTTGCTTCGCAGATTGGTTTTATCCCCAACCAGACCGGTACCGGGCTG
GAGATGAAAGCAATTGCAGCCTGCGTGCTGGGCGGCATTAGTTTGCTCGGCGGTTCCGGTGCGATCATCGGTGCGGTACT
CGGCGCATGGTTCCTGACGCAGATCGATAGCGTACTGGTGCTGTTGCGCATTCCGGCATGGTGGAACGATTTTATCGCGG
GCCTCGTGCTGCTGGCGGTGCTGGTGTTTGATGGACGCCTGCGTTGTGCGCTGGAACGTAATCTACGGCGGCAAAAATAT
GCCCGCTTTATGACGCCACCGCCATCCGTTAAACCCGCTTCGTCAGGTAAAAAACGGGAGGCCGCATAA

Upstream 100 bases:

>100_bases
ATCAGGGCGAAATTGCCCACTCTGCACTGACCGGGCGCGATATTAATGTCGAGACTATTATGCGCGTTGCCTTCGGCGAT
AGTCAGCGTCAGGAGGCGTC

Downstream 100 bases:

>100_bases
TGCGTATTCGCTACGGTTGGGAACTGGCTCTTGCCGCACTGCTCGTTATTGAGATTGTCGCATTTGGTGCAATTAACCCG
CGGATGTTAGATCTCAATAT

Product: autoinducer-2 ABC transporter, permease protein LsrC

Products: NA

Alternate protein names: AI-2 import system permease protein lsrC [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSVQTLTMVYSSAQILILLAMGATLVMLTRNIDVSVGSITGMCAVLLGM
LLNAGYSLPVACVTTLLLGLLAGFFNGVLVAWLKIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLFGVS
AIGWLTIILVAFMAWLLAKTAFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQTGTGL
EMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQIDSVLVLLRIPAWWNDFIAGLVLLAVLVFDGRLRCALERNLRRQKY
ARFMTPPPSVKPASSGKKREAA

Sequences:

>Translated_342_residues
MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSVQTLTMVYSSAQILILLAMGATLVMLTRNIDVSVGSITGMCAVLLGM
LLNAGYSLPVACVTTLLLGLLAGFFNGVLVAWLKIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLFGVS
AIGWLTIILVAFMAWLLAKTAFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQTGTGL
EMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQIDSVLVLLRIPAWWNDFIAGLVLLAVLVFDGRLRCALERNLRRQKY
ARFMTPPPSVKPASSGKKREAA
>Mature_342_residues
MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSVQTLTMVYSSAQILILLAMGATLVMLTRNIDVSVGSITGMCAVLLGM
LLNAGYSLPVACVTTLLLGLLAGFFNGVLVAWLKIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLFGVS
AIGWLTIILVAFMAWLLAKTAFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQTGTGL
EMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQIDSVLVLLRIPAWWNDFIAGLVLLAVLVFDGRLRCALERNLRRQKY
ARFMTPPPSVKPASSGKKREAA

Specific function: Part of the ABC transporter complex lsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787793, Length=342, Percent_Identity=99.4152046783626, Blast_Score=664, Evalue=0.0,
Organism=Escherichia coli, GI1789992, Length=362, Percent_Identity=30.6629834254144, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI145693152, Length=267, Percent_Identity=34.4569288389513, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1790191, Length=308, Percent_Identity=31.1688311688312, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788896, Length=303, Percent_Identity=30.6930693069307, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1790524, Length=277, Percent_Identity=27.0758122743682, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI145693214, Length=283, Percent_Identity=34.2756183745583, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI87082395, Length=325, Percent_Identity=29.8461538461538, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787794, Length=311, Percent_Identity=30.5466237942122, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788471, Length=307, Percent_Identity=29.6416938110749, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 36459; Mature: 36459

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSVQTLTMVYSSAQILILLAMGATLVMLT
CCCCCCCCCHHHHHHHHHHHHHHCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNIDVSVGSITGMCAVLLGMLLNAGYSLPVACVTTLLLGLLAGFFNGVLVAWLKIPAIVA
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLFGVSAIGWLTIILVAFMAWLLAKT
HHHHHHHHHHHHEEECCCHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQTGTGL
HHCCCEECCCCCCCHHHHHCCHHHHHEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQIDSVLVLLRIPAWWNDFIAGLVLLAV
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LVFDGRLRCALERNLRRQKYARFMTPPPSVKPASSGKKREAA
HHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSVQTLTMVYSSAQILILLAMGATLVMLT
CCCCCCCCCHHHHHHHHHHHHHHCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNIDVSVGSITGMCAVLLGMLLNAGYSLPVACVTTLLLGLLAGFFNGVLVAWLKIPAIVA
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLFGVSAIGWLTIILVAFMAWLLAKT
HHHHHHHHHHHHEEECCCHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQTGTGL
HHCCCEECCCCCCCHHHHHCCHHHHHEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQIDSVLVLLRIPAWWNDFIAGLVLLAV
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LVFDGRLRCALERNLRRQKYARFMTPPPSVKPASSGKKREAA
HHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]