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The map label for this gene is yddK [H]

Identifier: 157160946

GI number: 157160946

Start: 1561196

End: 1562527

Strand: Reverse

Name: yddK [H]

Synonym: EcHS_A1554

Alternate gene names: 157160946

Gene position: 1562527-1561196 (Counterclockwise)

Preceding gene: 157160947

Following gene: 157160945

Centisome position: 33.65

GC content: 33.41

Gene sequence:

>1332_bases
ATGATCACTGACCTTATATTACACAATCATCCCAGGATGAAAACAATCACTTTAAACGACAACCATATTGCACATTTAAA
CGCCAAAAACACTACAAAACTGGAATATTTAAACTTAAGCAATAACAATTTACTGCCAACCAATGACATTGATCAACTAA
TATCATCAAAGCATCTTTGGCATGTATTAGTTAACGGCATCAACAATGATCCACTTGCACAAATGCAGTACTGGACTGCA
GTAAGAAATATAATTGATGACACTAATGAAGTGACCATTGATTTATCAGGACTTAATTTAACCACTCAACCACCAGGGCT
GCAAAACTTCACCTCTATCAATCTTGATAATAACCAACTCACACATTTTGATGCAACCAACTACGATAGACTCGTAAAGC
TAAGTCTGAATAGTAATACTCTTGAGTCAATAAATTTTCCTCAAGGCAGAAATGTAAGTATTACACATATATCTATGAAT
AATAATGCTCTCAGAAATATTGATATAGATAGGCTTTCATCAGTTACTTATTTTAGTGCGGCACATAATCAACTAGAGTT
TGTGCAATTAGAATCTTGCGAATGGCTGCAATACCTGAATCTCAGCCATAATCAATTAACTGATATTGTTGCAGGTAATA
AAGATGAACTCTTACTGCTGGATCTATCCCATAATAAACTAACAAGTTTACACAATGACTTATTTCCCAACTTGAATACG
TTACTTATTAACAACAATTTGCTTTCTGAAATTAAAATATTCTATAGCAACTTCTGCAATGTTCAGACATTAAACGCTGC
TAACAACCAGTTGAAATATATAAATCTTGATTTCCTGACTTATCTTCCATCTATCAAAAGTTTAAGACTGGACAATAATA
AAATAACCCACACTGATACTAATAATACATCCGATATTGGAACTTTATTCCCCATAATAAAACAGAGCAAAAACTTAAAT
TTTTTAAATGTTTCTGGGAAGAACAATTGCCCTACTATGCAGCTCATGTTATTTAATTTATTTTCCCCAGCACTTAAGCT
TAATACTGGCCCGGCAATTCTTTCGCCTGGTGCATTTGAAGTTCACTCTGACGGAATAGATGTGGATAACGAATTGTTTC
ACTATCCTATTAAAAAAGCATATACCCCATATAATATACACACTTACAAGACAGAGGAAGTTGTAAACCAGAGGAATATA
AAAGTTAAAAACATGACCTTAGATGAAATAAACAATACTTACTGTAATAACGATTATTACAATCAGGCAATAAGAGAGGA
ACCGATAGACCTTCTGGACAGATCGTTTTCCTCCAGTTCATGGCCTTTTTAG

Upstream 100 bases:

>100_bases
TTGGTTTTGGTCACTGGGAATATGATTTTAAAGGCTATAACGATGAAGCCAACGGCTCGCGCGGCAAGAATCTCTGATTG
AGTTAAGTGCCCATCACAAT

Downstream 100 bases:

>100_bases
TGAATAAATCATCACTAATTCTATAAGTGTCTGGTCTTGTTGATAATATAGTTAATATGTAACCCTTTAGATTCACGATC
TGAAGGGTTGAAACATGACA

Product: leucine-rich repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MITDLILHNHPRMKTITLNDNHIAHLNAKNTTKLEYLNLSNNNLLPTNDIDQLISSKHLWHVLVNGINNDPLAQMQYWTA
VRNIIDDTNEVTIDLSGLNLTTQPPGLQNFTSINLDNNQLTHFDATNYDRLVKLSLNSNTLESINFPQGRNVSITHISMN
NNALRNIDIDRLSSVTYFSAAHNQLEFVQLESCEWLQYLNLSHNQLTDIVAGNKDELLLLDLSHNKLTSLHNDLFPNLNT
LLINNNLLSEIKIFYSNFCNVQTLNAANNQLKYINLDFLTYLPSIKSLRLDNNKITHTDTNNTSDIGTLFPIIKQSKNLN
FLNVSGKNNCPTMQLMLFNLFSPALKLNTGPAILSPGAFEVHSDGIDVDNELFHYPIKKAYTPYNIHTYKTEEVVNQRNI
KVKNMTLDEINNTYCNNDYYNQAIREEPIDLLDRSFSSSSWPF

Sequences:

>Translated_443_residues
MITDLILHNHPRMKTITLNDNHIAHLNAKNTTKLEYLNLSNNNLLPTNDIDQLISSKHLWHVLVNGINNDPLAQMQYWTA
VRNIIDDTNEVTIDLSGLNLTTQPPGLQNFTSINLDNNQLTHFDATNYDRLVKLSLNSNTLESINFPQGRNVSITHISMN
NNALRNIDIDRLSSVTYFSAAHNQLEFVQLESCEWLQYLNLSHNQLTDIVAGNKDELLLLDLSHNKLTSLHNDLFPNLNT
LLINNNLLSEIKIFYSNFCNVQTLNAANNQLKYINLDFLTYLPSIKSLRLDNNKITHTDTNNTSDIGTLFPIIKQSKNLN
FLNVSGKNNCPTMQLMLFNLFSPALKLNTGPAILSPGAFEVHSDGIDVDNELFHYPIKKAYTPYNIHTYKTEEVVNQRNI
KVKNMTLDEINNTYCNNDYYNQAIREEPIDLLDRSFSSSSWPF
>Mature_443_residues
MITDLILHNHPRMKTITLNDNHIAHLNAKNTTKLEYLNLSNNNLLPTNDIDQLISSKHLWHVLVNGINNDPLAQMQYWTA
VRNIIDDTNEVTIDLSGLNLTTQPPGLQNFTSINLDNNQLTHFDATNYDRLVKLSLNSNTLESINFPQGRNVSITHISMN
NNALRNIDIDRLSSVTYFSAAHNQLEFVQLESCEWLQYLNLSHNQLTDIVAGNKDELLLLDLSHNKLTSLHNDLFPNLNT
LLINNNLLSEIKIFYSNFCNVQTLNAANNQLKYINLDFLTYLPSIKSLRLDNNKITHTDTNNTSDIGTLFPIIKQSKNLN
FLNVSGKNNCPTMQLMLFNLFSPALKLNTGPAILSPGAFEVHSDGIDVDNELFHYPIKKAYTPYNIHTYKTEEVVNQRNI
KVKNMTLDEINNTYCNNDYYNQAIREEPIDLLDRSFSSSSWPF

Specific function: Unknown

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 9 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Escherichia coli, GI1787744, Length=111, Percent_Identity=98.1981981981982, Blast_Score=229, Evalue=3e-61,
Organism=Drosophila melanogaster, GI281362655, Length=300, Percent_Identity=24.3333333333333, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281362653, Length=300, Percent_Identity=24.3333333333333, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281362657, Length=300, Percent_Identity=24.3333333333333, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281362651, Length=300, Percent_Identity=24.3333333333333, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24650334, Length=300, Percent_Identity=24.3333333333333, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24650332, Length=300, Percent_Identity=24.3333333333333, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24650330, Length=300, Percent_Identity=24.3333333333333, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI62472958, Length=300, Percent_Identity=24.3333333333333, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI116007092, Length=300, Percent_Identity=24.3333333333333, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001611 [H]

Pfam domain/function: PF00560 LRR_1 [H]

EC number: NA

Molecular weight: Translated: 50605; Mature: 50605

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITDLILHNHPRMKTITLNDNHIAHLNAKNTTKLEYLNLSNNNLLPTNDIDQLISSKHLW
CCCEEEECCCCCEEEEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHCCCCEE
HVLVNGINNDPLAQMQYWTAVRNIIDDTNEVTIDLSGLNLTTQPPGLQNFTSINLDNNQL
EHEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCEEECCCCCCCCCEEEECCCCEE
THFDATNYDRLVKLSLNSNTLESINFPQGRNVSITHISMNNNALRNIDIDRLSSVTYFSA
EEECCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCEEECCHHHHCCEEEEHH
AHNQLEFVQLESCEWLQYLNLSHNQLTDIVAGNKDELLLLDLSHNKLTSLHNDLFPNLNT
CCCCEEEEEECCCCHHHHHCCCCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCEE
LLINNNLLSEIKIFYSNFCNVQTLNAANNQLKYINLDFLTYLPSIKSLRLDNNKITHTDT
EEEECCHHHHHHHHHHCCCCEEEECCCCCEEEEEEEHHHHHCCCHHEEEECCCEEEECCC
NNTSDIGTLFPIIKQSKNLNFLNVSGKNNCPTMQLMLFNLFSPALKLNTGPAILSPGAFE
CCCCCHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHCCCEEECCCCCEECCCCEE
VHSDGIDVDNELFHYPIKKAYTPYNIHTYKTEEVVNQRNIKVKNMTLDEINNTYCNNDYY
EECCCCCCCCHHEECCHHHCCCCCEEEEEEHHHHHCCCCEEEEEEEHHHCCCCCCCCHHH
NQAIREEPIDLLDRSFSSSSWPF
HHHHHHCCHHHHHCCCCCCCCCC
>Mature Secondary Structure
MITDLILHNHPRMKTITLNDNHIAHLNAKNTTKLEYLNLSNNNLLPTNDIDQLISSKHLW
CCCEEEECCCCCEEEEEECCCEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHCCCCEE
HVLVNGINNDPLAQMQYWTAVRNIIDDTNEVTIDLSGLNLTTQPPGLQNFTSINLDNNQL
EHEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCEEECCCCCCCCCEEEECCCCEE
THFDATNYDRLVKLSLNSNTLESINFPQGRNVSITHISMNNNALRNIDIDRLSSVTYFSA
EEECCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCEEECCHHHHCCEEEEHH
AHNQLEFVQLESCEWLQYLNLSHNQLTDIVAGNKDELLLLDLSHNKLTSLHNDLFPNLNT
CCCCEEEEEECCCCHHHHHCCCCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCEE
LLINNNLLSEIKIFYSNFCNVQTLNAANNQLKYINLDFLTYLPSIKSLRLDNNKITHTDT
EEEECCHHHHHHHHHHCCCCEEEECCCCCEEEEEEEHHHHHCCCHHEEEECCCEEEECCC
NNTSDIGTLFPIIKQSKNLNFLNVSGKNNCPTMQLMLFNLFSPALKLNTGPAILSPGAFE
CCCCCHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHCCCEEECCCCCEECCCCEE
VHSDGIDVDNELFHYPIKKAYTPYNIHTYKTEEVVNQRNIKVKNMTLDEINNTYCNNDYY
EECCCCCCCCHHEECCHHHCCCCCEEEEEEHHHHHCCCCEEEEEEEHHHCCCCCCCCHHH
NQAIREEPIDLLDRSFSSSSWPF
HHHHHHCCHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]