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The map label for this gene is gapC [H]

Identifier: 157160894

GI number: 157160894

Start: 1510141

End: 1511142

Strand: Reverse

Name: gapC [H]

Synonym: EcHS_A1499

Alternate gene names: 157160894

Gene position: 1511142-1510141 (Counterclockwise)

Preceding gene: 157160897

Following gene: 157160890

Centisome position: 32.54

GC content: 48.0

Gene sequence:

>1002_bases
ATGAGTAAAGTTGGTATTAACGGTTTTGGTCGTATCGGTCGACTGGTGTTGCGTCGATTACTTGAAGTCAAAAGCAACAT
AGACGTTGTCGCTATTAATGATCTCACTTCCCCAAAAATTCTCGCCTACCTGCTGAAACATGATTCAAACTACGGACCAT
TCCCCTGGAGCGTTGATTTTACGGAAGATTCACTTATCGTTGATGGGAAAAGTATCGCGGTTTACGCCGAAAAAGAGGCT
AAAAATATTCCGTGGAAAGCGAAAGGTGCAGAAATCATTGTCGAATGTACTGGCTTTTATACCTCCGCCGAGAAATCGCA
GGCGCATCTTGATGCTGGTGCGAAGAAGGTGTTGATTTCCGCCCCTGCCGGTGAAATGAAAACTATCGTTTATAACGTCA
ATGACGACACTCTGGATGGCAACGACACCATTGTTTCCGTGGCGTCATGCACCACTAACTGTCTTGCGCCGATGGCCAAA
GCCTTGCATGACAGTTTCGGGATAGAAGTCGGCACGATGACGACCATTCATGCCTATACTGGCACCCAGTCACTGGTGGA
TGGCCCGCGTGGTAAAGATTTACGTGCTTCACGCGCAGCGGCAGAAAATATCATTCCCCACACTACGGGGGCGGCAAAAG
CCATTGGTCTGGTGATCCCGGAACTGAGCGGCAAACTGAAAGGTCATGCGCAACGCGTGCCGGTGAAAACAGGTTCGGTC
ACTGAACTGGTATCGATTCTCGGAAAAAAAGTGACTGCCGAAGAGGTGAATAACGCACTTAAACAAGCAACCACCAATAA
CGAGTCATTTGGTTATACCGATGAAGAAATAGTCTCTTCCGATATCATTGGCAGCCATTTCGGTTCGGTGTTTGATGCCA
CGCAAACGGAAATTACCGCCGTGGGCGATTTACAACTGGTGAAAACGGTCGCCTGGTACGATAACGAATATGGCTTCGTC
ACACAGCTTATTCGCACCCTCGAAAAATTCGCTAAACTCTGA

Upstream 100 bases:

>100_bases
TTACGTTTCACTGTGAGAATGGAGATTGCCCATCCCGCCATCCTGGTCTAAGCCTGGAAAGGATCAATTTTCATCCGAAC
GTTCCTGACAGGAGAAAACC

Downstream 100 bases:

>100_bases
CGCGCACAGGCGGAGGAAAAAACCTCCGCCTCTTTCACTCATTAAGACTGTAAATAAACCACCTGGGTCTGCAGATATTC
ATGCAAGCCATGTTTACCAT

Product: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)

Products: NA

Alternate protein names: GAPDH-C [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSKVGINGFGRIGRLVLRRLLEVKSNIDVVAINDLTSPKILAYLLKHDSNYGPFPWSVDFTEDSLIVDGKSIAVYAEKEA
KNIPWKAKGAEIIVECTGFYTSAEKSQAHLDAGAKKVLISAPAGEMKTIVYNVNDDTLDGNDTIVSVASCTTNCLAPMAK
ALHDSFGIEVGTMTTIHAYTGTQSLVDGPRGKDLRASRAAAENIIPHTTGAAKAIGLVIPELSGKLKGHAQRVPVKTGSV
TELVSILGKKVTAEEVNNALKQATTNNESFGYTDEEIVSSDIIGSHFGSVFDATQTEITAVGDLQLVKTVAWYDNEYGFV
TQLIRTLEKFAKL

Sequences:

>Translated_333_residues
MSKVGINGFGRIGRLVLRRLLEVKSNIDVVAINDLTSPKILAYLLKHDSNYGPFPWSVDFTEDSLIVDGKSIAVYAEKEA
KNIPWKAKGAEIIVECTGFYTSAEKSQAHLDAGAKKVLISAPAGEMKTIVYNVNDDTLDGNDTIVSVASCTTNCLAPMAK
ALHDSFGIEVGTMTTIHAYTGTQSLVDGPRGKDLRASRAAAENIIPHTTGAAKAIGLVIPELSGKLKGHAQRVPVKTGSV
TELVSILGKKVTAEEVNNALKQATTNNESFGYTDEEIVSSDIIGSHFGSVFDATQTEITAVGDLQLVKTVAWYDNEYGFV
TQLIRTLEKFAKL
>Mature_332_residues
SKVGINGFGRIGRLVLRRLLEVKSNIDVVAINDLTSPKILAYLLKHDSNYGPFPWSVDFTEDSLIVDGKSIAVYAEKEAK
NIPWKAKGAEIIVECTGFYTSAEKSQAHLDAGAKKVLISAPAGEMKTIVYNVNDDTLDGNDTIVSVASCTTNCLAPMAKA
LHDSFGIEVGTMTTIHAYTGTQSLVDGPRGKDLRASRAAAENIIPHTTGAAKAIGLVIPELSGKLKGHAQRVPVKTGSVT
ELVSILGKKVTAEEVNNALKQATTNNESFGYTDEEIVSSDIIGSHFGSVFDATQTEITAVGDLQLVKTVAWYDNEYGFVT
QLIRTLEKFAKL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=331, Percent_Identity=46.5256797583082, Blast_Score=285, Evalue=4e-77,
Organism=Homo sapiens, GI7669492, Length=332, Percent_Identity=44.578313253012, Blast_Score=278, Evalue=6e-75,
Organism=Escherichia coli, GI1788079, Length=333, Percent_Identity=46.2462462462462, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1789295, Length=330, Percent_Identity=40.3030303030303, Blast_Score=237, Evalue=9e-64,
Organism=Caenorhabditis elegans, GI32566163, Length=337, Percent_Identity=46.2908011869436, Blast_Score=275, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=46.2908011869436, Blast_Score=275, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17534677, Length=335, Percent_Identity=47.4626865671642, Blast_Score=274, Evalue=4e-74,
Organism=Caenorhabditis elegans, GI17534679, Length=335, Percent_Identity=46.865671641791, Blast_Score=274, Evalue=6e-74,
Organism=Saccharomyces cerevisiae, GI6321631, Length=336, Percent_Identity=45.5357142857143, Blast_Score=293, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6322468, Length=339, Percent_Identity=46.3126843657817, Blast_Score=290, Evalue=2e-79,
Organism=Saccharomyces cerevisiae, GI6322409, Length=336, Percent_Identity=44.9404761904762, Blast_Score=286, Evalue=3e-78,
Organism=Drosophila melanogaster, GI19922412, Length=327, Percent_Identity=46.177370030581, Blast_Score=289, Evalue=2e-78,
Organism=Drosophila melanogaster, GI17933600, Length=331, Percent_Identity=47.1299093655589, Blast_Score=285, Evalue=4e-77,
Organism=Drosophila melanogaster, GI18110149, Length=331, Percent_Identity=47.1299093655589, Blast_Score=285, Evalue=4e-77,
Organism=Drosophila melanogaster, GI85725000, Length=331, Percent_Identity=46.8277945619335, Blast_Score=282, Evalue=2e-76,
Organism=Drosophila melanogaster, GI22023983, Length=331, Percent_Identity=46.8277945619335, Blast_Score=282, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35749; Mature: 35618

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00071 GAPDH ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVGINGFGRIGRLVLRRLLEVKSNIDVVAINDLTSPKILAYLLKHDSNYGPFPWSVDF
CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEC
TEDSLIVDGKSIAVYAEKEAKNIPWKAKGAEIIVECTGFYTSAEKSQAHLDAGAKKVLIS
CCCCEEECCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHCCCCCEEEEE
APAGEMKTIVYNVNDDTLDGNDTIVSVASCTTNCLAPMAKALHDSFGIEVGTMTTIHAYT
CCCCCEEEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCEEECCEEEEEEEC
GTQSLVDGPRGKDLRASRAAAENIIPHTTGAAKAIGLVIPELSGKLKGHAQRVPVKTGSV
CCHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHEEECCCCCCCCCCCEECCCCCCCH
TELVSILGKKVTAEEVNNALKQATTNNESFGYTDEEIVSSDIIGSHFGSVFDATQTEITA
HHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEE
VGDLQLVKTVAWYDNEYGFVTQLIRTLEKFAKL
ECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKVGINGFGRIGRLVLRRLLEVKSNIDVVAINDLTSPKILAYLLKHDSNYGPFPWSVDF
CCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEC
TEDSLIVDGKSIAVYAEKEAKNIPWKAKGAEIIVECTGFYTSAEKSQAHLDAGAKKVLIS
CCCCEEECCCEEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHCCCCCEEEEE
APAGEMKTIVYNVNDDTLDGNDTIVSVASCTTNCLAPMAKALHDSFGIEVGTMTTIHAYT
CCCCCEEEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCEEECCEEEEEEEC
GTQSLVDGPRGKDLRASRAAAENIIPHTTGAAKAIGLVIPELSGKLKGHAQRVPVKTGSV
CCHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHEEECCCCCCCCCCCEECCCCCCCH
TELVSILGKKVTAEEVNNALKQATTNNESFGYTDEEIVSSDIIGSHFGSVFDATQTEITA
HHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEE
VGDLQLVKTVAWYDNEYGFVTQLIRTLEKFAKL
ECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]