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The map label for this gene is ydbC

Identifier: 157160884

GI number: 157160884

Start: 1494648

End: 1495508

Strand: Direct

Name: ydbC

Synonym: EcHS_A1489

Alternate gene names: 157160884

Gene position: 1494648-1495508 (Clockwise)

Preceding gene: 157160883

Following gene: 157160885

Centisome position: 32.19

GC content: 52.96

Gene sequence:

>861_bases
ATGAGCAGCAATACATTTACTCTCGGTACAAAATCCGTTAACCGTCTTGGTTATGGCGCGATGCAACTGGCAGGTCCTGG
AGTTTTTGGCCCCCCACGAGATCGCCACGTCGCTATAACCGTGCTGCGTGAGGCGCTGGCATTGGGCGTCAATCATATTG
ATACCAGCGACTTTTATGGTCCGCACGTCACCAATCAGATTATCCGCGAAGCGCTTTATCCTTACTCTGACGACCTGACA
ATTGTCACTAAAATTGGTGCGCGGCGTGGAGAGGACGCATCCTGGTTGCCCGCATTTTCTCCGGCAGAGCTGCAAAAAGC
GGTGCACGATAATCTACGTAATCTCGGGCTGGACGTGCTGGATGTGGTTAACCTGCGCGTTATGATGGGGGATGGTCATG
GCCCAGCGGAAGGATCGATTGAGGCCAGCCTGACCGTGCTGGCAGAGATGCAACAACAAGGCTTGGTAAAACATATTGGC
CTGAGCAACGTCACACCGACGCAGGTTGCAGAGGCGCGCAAGATTGCCGAAATTGTCTGTGTGCAAAACGAATACAACAT
CGCGCACCGTGCTGATGATGCAATGATTGATGCTTTGGCCCACGATGGCATTGCCTACGTGCCGTTCTTCCCGCTCGGGG
GCTTTACACCGCTGCAATCGTCCACACTTTCCGATGTTGCTGCGAGCCTGGGTGCAACACCCATGCAGGTGGCGCTGGCG
TGGCTGTTACAACGTTCACCGAATATTTTGCTGATCCCAGGGACGTCTTCGGTTGCGCATTTACGGGAGAATATGGCTGC
TGAAAAATTGCATCTTTCTGAGGAAGTGTTGTCTACGTTGGATGGTATTTCGCGAGAATAA

Upstream 100 bases:

>100_bases
GCAACTCATCCAGTAATCTTGTTTACACCTTCGCATTATTTATCTCTTTTCGTTTCTATACTGATTTTTCTTAATCCGTT
TTATTACAGGGCAGGGTGCG

Downstream 100 bases:

>100_bases
CGAATATACAAAAGGGAAAGATGCATTTCCCTTTTGTTTCTTTTTTAATGGCATGGAGTGCATATGTTTAAGGCCAGGAT
TTGCGGCTGGATAGGTTTAC

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MSSNTFTLGTKSVNRLGYGAMQLAGPGVFGPPRDRHVAITVLREALALGVNHIDTSDFYGPHVTNQIIREALYPYSDDLT
IVTKIGARRGEDASWLPAFSPAELQKAVHDNLRNLGLDVLDVVNLRVMMGDGHGPAEGSIEASLTVLAEMQQQGLVKHIG
LSNVTPTQVAEARKIAEIVCVQNEYNIAHRADDAMIDALAHDGIAYVPFFPLGGFTPLQSSTLSDVAASLGATPMQVALA
WLLQRSPNILLIPGTSSVAHLRENMAAEKLHLSEEVLSTLDGISRE

Sequences:

>Translated_286_residues
MSSNTFTLGTKSVNRLGYGAMQLAGPGVFGPPRDRHVAITVLREALALGVNHIDTSDFYGPHVTNQIIREALYPYSDDLT
IVTKIGARRGEDASWLPAFSPAELQKAVHDNLRNLGLDVLDVVNLRVMMGDGHGPAEGSIEASLTVLAEMQQQGLVKHIG
LSNVTPTQVAEARKIAEIVCVQNEYNIAHRADDAMIDALAHDGIAYVPFFPLGGFTPLQSSTLSDVAASLGATPMQVALA
WLLQRSPNILLIPGTSSVAHLRENMAAEKLHLSEEVLSTLDGISRE
>Mature_285_residues
SSNTFTLGTKSVNRLGYGAMQLAGPGVFGPPRDRHVAITVLREALALGVNHIDTSDFYGPHVTNQIIREALYPYSDDLTI
VTKIGARRGEDASWLPAFSPAELQKAVHDNLRNLGLDVLDVVNLRVMMGDGHGPAEGSIEASLTVLAEMQQQGLVKHIGL
SNVTPTQVAEARKIAEIVCVQNEYNIAHRADDAMIDALAHDGIAYVPFFPLGGFTPLQSSTLSDVAASLGATPMQVALAW
LLQRSPNILLIPGTSSVAHLRENMAAEKLHLSEEVLSTLDGISRE

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family

Homologues:

Organism=Escherichia coli, GI1787674, Length=286, Percent_Identity=100, Blast_Score=585, Evalue=1e-168,
Organism=Escherichia coli, GI87081735, Length=328, Percent_Identity=28.0487804878049, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788070, Length=309, Percent_Identity=25.5663430420712, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786400, Length=257, Percent_Identity=27.6264591439689, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788081, Length=260, Percent_Identity=23.0769230769231, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YDBC_ECOLI (P25906)

Other databases:

- EMBL:   X62680
- EMBL:   U00096
- EMBL:   AP009048
- EMBL:   X97452
- PIR:   A48399
- RefSeq:   AP_002031.1
- RefSeq:   NP_415924.1
- ProteinModelPortal:   P25906
- SMR:   P25906
- DIP:   DIP-11632N
- IntAct:   P25906
- STRING:   P25906
- SWISS-2DPAGE:   P25906
- EnsemblBacteria:   EBESCT00000002131
- EnsemblBacteria:   EBESCT00000014323
- GeneID:   945980
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW1403
- KEGG:   eco:b1406
- EchoBASE:   EB1285
- EcoGene:   EG11309
- eggNOG:   COG0667
- GeneTree:   EBGT00050000009263
- HOGENOM:   HBG605727
- OMA:   MFDVHGP
- ProtClustDB:   PRK10376
- BioCyc:   EcoCyc:EG11309-MONOMER
- Genevestigator:   P25906
- InterPro:   IPR001395
- InterPro:   IPR023210
- Gene3D:   G3DSA:3.20.20.100
- PANTHER:   PTHR11732

Pfam domain/function: PF00248 Aldo_ket_red; SSF51430 Aldo/ket_red

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30706; Mature: 30575

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: ACT_SITE 59-59

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNTFTLGTKSVNRLGYGAMQLAGPGVFGPPRDRHVAITVLREALALGVNHIDTSDFYG
CCCCEEEECCHHHHHHCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
PHVTNQIIREALYPYSDDLTIVTKIGARRGEDASWLPAFSPAELQKAVHDNLRNLGLDVL
CHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHH
DVVNLRVMMGDGHGPAEGSIEASLTVLAEMQQQGLVKHIGLSNVTPTQVAEARKIAEIVC
HHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHE
VQNEYNIAHRADDAMIDALAHDGIAYVPFFPLGGFTPLQSSTLSDVAASLGATPMQVALA
ECCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
WLLQRSPNILLIPGTSSVAHLRENMAAEKLHLSEEVLSTLDGISRE
HHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SSNTFTLGTKSVNRLGYGAMQLAGPGVFGPPRDRHVAITVLREALALGVNHIDTSDFYG
CCCEEEECCHHHHHHCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
PHVTNQIIREALYPYSDDLTIVTKIGARRGEDASWLPAFSPAELQKAVHDNLRNLGLDVL
CHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHH
DVVNLRVMMGDGHGPAEGSIEASLTVLAEMQQQGLVKHIGLSNVTPTQVAEARKIAEIVC
HHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHE
VQNEYNIAHRADDAMIDALAHDGIAYVPFFPLGGFTPLQSSTLSDVAASLGATPMQVALA
ECCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
WLLQRSPNILLIPGTSSVAHLRENMAAEKLHLSEEVLSTLDGISRE
HHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1665988; 9097039; 9278503; 9748275