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The map label for this gene is feaR [H]

Identifier: 157160866

GI number: 157160866

Start: 1469570

End: 1470475

Strand: Reverse

Name: feaR [H]

Synonym: EcHS_A1471

Alternate gene names: 157160866

Gene position: 1470475-1469570 (Counterclockwise)

Preceding gene: 157160868

Following gene: 157160862

Centisome position: 31.67

GC content: 49.01

Gene sequence:

>906_bases
ATGAACCCCGCAGTGGATAATGAGTTTCAGCAATGGCTTTCCCAAATCAATCAGGTATGCGGAAATTTTACCGGACGCCT
GCTGACTGAGCGTTACACGGGTGTACTGGACACGCATTTTGCCAAAGGACTAAAGCTGAGTACCGTGACAACCAGCGGGG
TGAATTTATCCCGCACCTGGCAGGAAGTAAAAGGCAGCGACGATGCCTGGTTTTACACCGTTTTTCAGCTTAGTGGTCAG
GCAATAATGGAGCAGGATGAGCGTCAGGTGCAGATTGGCGCAGGCGATATTACGTTACTCGATGCCTCACGCCCCTGTTC
GCTTTACTGGCAGGAGTCTTCTAAACAGATTTCATTACTTTTGCCACGCACTCTGCTGGAACAATATTTTCCCCATCAAA
AACCTGTCTGCGCAGAAAGACTGGACGCTGACTTACCCATGGTGCAACTCAGTCATCGTCTGTTACAGGAAAGCATGAAT
AACCCGGCACTTTCTGAAACAGAAAGTGAAGCTGCGCTACAGGCGATGGTGTGTCTGCTGCGCCCGGTACTTCATCAGCG
GGAATCTGTCCAACCTCGCCGTGAACGTCAGTTTCAAAAAGTGGTTACGTTGATAGACGATAATATTCGCGAAGAGATAT
TACGCCCGGAGTGGATAGCCGCAGAGACGGGTATGTCAGTACGTAGTTTGTACCGAATGTTTGCCGATAAAGGTTTGGTC
GTCGCGCAATATATTCGTAACCGTCGTCTCGATTTTTGTGCAGATGCGATTCGCCATGCCGCAGATGATGAAAAACTGGC
AGGCATCGGCTTTCATTGGGGATTTTCTGACCAGAGTCATTTTTCAACGGTATTTAAGCAACGCTTTGGGATGACGCCAG
GCGAGTATCGACGTAAATTCCGCTAA

Upstream 100 bases:

>100_bases
TGCCTGACAAGACTTATTTCCTATAGTCAGGCTCATTAGCTTCGTTTATCGCAACACAAATGCAACAATAAAAATACATT
TCACAGAGCGAAAACGTGCC

Downstream 100 bases:

>100_bases
CTAATTCGCGTTGCATGTACTGCAACGCCAATTAGTTAAAACAGATATTTGACTACGCATATTTCAGGGCAAAAGGCAAT
TTGACAGGAGTTTTTGAATA

Product: DNA-binding transcriptional activator FeaR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MNPAVDNEFQQWLSQINQVCGNFTGRLLTERYTGVLDTHFAKGLKLSTVTTSGVNLSRTWQEVKGSDDAWFYTVFQLSGQ
AIMEQDERQVQIGAGDITLLDASRPCSLYWQESSKQISLLLPRTLLEQYFPHQKPVCAERLDADLPMVQLSHRLLQESMN
NPALSETESEAALQAMVCLLRPVLHQRESVQPRRERQFQKVVTLIDDNIREEILRPEWIAAETGMSVRSLYRMFADKGLV
VAQYIRNRRLDFCADAIRHAADDEKLAGIGFHWGFSDQSHFSTVFKQRFGMTPGEYRRKFR

Sequences:

>Translated_301_residues
MNPAVDNEFQQWLSQINQVCGNFTGRLLTERYTGVLDTHFAKGLKLSTVTTSGVNLSRTWQEVKGSDDAWFYTVFQLSGQ
AIMEQDERQVQIGAGDITLLDASRPCSLYWQESSKQISLLLPRTLLEQYFPHQKPVCAERLDADLPMVQLSHRLLQESMN
NPALSETESEAALQAMVCLLRPVLHQRESVQPRRERQFQKVVTLIDDNIREEILRPEWIAAETGMSVRSLYRMFADKGLV
VAQYIRNRRLDFCADAIRHAADDEKLAGIGFHWGFSDQSHFSTVFKQRFGMTPGEYRRKFR
>Mature_301_residues
MNPAVDNEFQQWLSQINQVCGNFTGRLLTERYTGVLDTHFAKGLKLSTVTTSGVNLSRTWQEVKGSDDAWFYTVFQLSGQ
AIMEQDERQVQIGAGDITLLDASRPCSLYWQESSKQISLLLPRTLLEQYFPHQKPVCAERLDADLPMVQLSHRLLQESMN
NPALSETESEAALQAMVCLLRPVLHQRESVQPRRERQFQKVVTLIDDNIREEILRPEWIAAETGMSVRSLYRMFADKGLV
VAQYIRNRRLDFCADAIRHAADDEKLAGIGFHWGFSDQSHFSTVFKQRFGMTPGEYRRKFR

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=301, Percent_Identity=99.3355481727575, Blast_Score=626, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 34621; Mature: 34621

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPAVDNEFQQWLSQINQVCGNFTGRLLTERYTGVLDTHFAKGLKLSTVTTSGVNLSRTW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHH
QEVKGSDDAWFYTVFQLSGQAIMEQDERQVQIGAGDITLLDASRPCSLYWQESSKQISLL
HHHCCCCCCEEEEHHHHCCHHHHCCCCCEEEECCCCEEEEECCCCCEEEECCCCCEEEHH
LPRTLLEQYFPHQKPVCAERLDADLPMVQLSHRLLQESMNNPALSETESEAALQAMVCLL
HHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
RPVLHQRESVQPRRERQFQKVVTLIDDNIREEILRPEWIAAETGMSVRSLYRMFADKGLV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHCCCHH
VAQYIRNRRLDFCADAIRHAADDEKLAGIGFHWGFSDQSHFSTVFKQRFGMTPGEYRRKF
HHHHHHHCCHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHCC
R
C
>Mature Secondary Structure
MNPAVDNEFQQWLSQINQVCGNFTGRLLTERYTGVLDTHFAKGLKLSTVTTSGVNLSRTW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHH
QEVKGSDDAWFYTVFQLSGQAIMEQDERQVQIGAGDITLLDASRPCSLYWQESSKQISLL
HHHCCCCCCEEEEHHHHCCHHHHCCCCCEEEECCCCEEEEECCCCCEEEECCCCCEEEHH
LPRTLLEQYFPHQKPVCAERLDADLPMVQLSHRLLQESMNNPALSETESEAALQAMVCLL
HHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
RPVLHQRESVQPRRERQFQKVVTLIDDNIREEILRPEWIAAETGMSVRSLYRMFADKGLV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHCCCHH
VAQYIRNRRLDFCADAIRHAADDEKLAGIGFHWGFSDQSHFSTVFKQRFGMTPGEYRRKF
HHHHHHHCCHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]