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The map label for this gene is ycjZ

Identifier: 157160839

GI number: 157160839

Start: 1439442

End: 1440341

Strand: Direct

Name: ycjZ

Synonym: EcHS_A1444

Alternate gene names: 157160839

Gene position: 1439442-1440341 (Clockwise)

Preceding gene: 157160836

Following gene: 157160841

Centisome position: 31.0

GC content: 46.56

Gene sequence:

>900_bases
ATGAAGCGTGAAGAAATCGCTGATCTGATGGCGTTTGTCGTCGTTGCAGAGGAGCGTAGCTTCACTCGTGCAGCAGCCCG
CCTGAGCATGGCGCAGTCAGCTTTAAGCCAGATAGTGCGTCGTATAGAAGAACGATTGGGATTGCGGCTTCTGACGCGAA
CCACGCGCAGCGTTGTTCCAACTGAAGCGGGCGAGCATCTTTTGTCTGTTCTTGGCCCTATGTTGCATGACATAGATTCA
GCCATGGCATCCCTGAGCGATCTGCAGAACCGCCCATCCGGGACAATACGTATTACTACTGTAGAACATGCAGCAAAAAC
GATATTGTTACCAGCAATGCGCACATTCCTGAAATCGCATCCTGAAATTGATATTCAGCTCACCATTGATTATGGTTTGA
CCGATGTCGTTTCTGAACGTTTTGATGCAGGCGTCCGTCTGGGTGGGGAGATGGATAAAGATATGATCGCCATTCGAATC
GGGCCAGATATACCAATGGCTATTGTTGGCTCACCGGATTATTTTTCTCGCCGAAGTGTTCCAACGTCAGTGTCACAATT
AATAGATCATCAGGCAATTAATTTGTATCTTCCCACATCGGGTACAGCAAATCGCTGGAGATTAATACGCGGTGGACGTG
AAGTTCGTGTTCGCATGGAAGGTCAGCTTTTACTGAATACGATAGACCTGATCATTGATGCTGCAATTGATGGGCATGGA
TTGGCGTATCTACCTTATGATCAGGTTGAGCGGGCTATTAAAGAAAAAAAACTGATACGTGTTTTGGATAAATTCACACC
AGATTTACCCGGTTATCACCTGTACTATCCACACCGTCGACATGCTGGCTCGGCATTCTCATTATTTATAGATAGGCTGA
AGTATAAAGGTGCTGTTTAG

Upstream 100 bases:

>100_bases
TGGTGATATCACTATAGATATTGATCATTAAGTTGATTAGACCCAAAATCATGATTAGACCTATCATTTAAATGATTAAT
AGATTGCATGGAGATACTGA

Downstream 100 bases:

>100_bases
CACTACTTGCTGATACATTAATTTAATTCTTCTCTTAACGTATTCTCAGTTCCTTTCAACGTTTTGGTCATTTTTTATTC
TTCGTACAATGGCGACAGAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MKREEIADLMAFVVVAEERSFTRAAARLSMAQSALSQIVRRIEERLGLRLLTRTTRSVVPTEAGEHLLSVLGPMLHDIDS
AMASLSDLQNRPSGTIRITTVEHAAKTILLPAMRTFLKSHPEIDIQLTIDYGLTDVVSERFDAGVRLGGEMDKDMIAIRI
GPDIPMAIVGSPDYFSRRSVPTSVSQLIDHQAINLYLPTSGTANRWRLIRGGREVRVRMEGQLLLNTIDLIIDAAIDGHG
LAYLPYDQVERAIKEKKLIRVLDKFTPDLPGYHLYYPHRRHAGSAFSLFIDRLKYKGAV

Sequences:

>Translated_299_residues
MKREEIADLMAFVVVAEERSFTRAAARLSMAQSALSQIVRRIEERLGLRLLTRTTRSVVPTEAGEHLLSVLGPMLHDIDS
AMASLSDLQNRPSGTIRITTVEHAAKTILLPAMRTFLKSHPEIDIQLTIDYGLTDVVSERFDAGVRLGGEMDKDMIAIRI
GPDIPMAIVGSPDYFSRRSVPTSVSQLIDHQAINLYLPTSGTANRWRLIRGGREVRVRMEGQLLLNTIDLIIDAAIDGHG
LAYLPYDQVERAIKEKKLIRVLDKFTPDLPGYHLYYPHRRHAGSAFSLFIDRLKYKGAV
>Mature_299_residues
MKREEIADLMAFVVVAEERSFTRAAARLSMAQSALSQIVRRIEERLGLRLLTRTTRSVVPTEAGEHLLSVLGPMLHDIDS
AMASLSDLQNRPSGTIRITTVEHAAKTILLPAMRTFLKSHPEIDIQLTIDYGLTDVVSERFDAGVRLGGEMDKDMIAIRI
GPDIPMAIVGSPDYFSRRSVPTSVSQLIDHQAINLYLPTSGTANRWRLIRGGREVRVRMEGQLLLNTIDLIIDAAIDGHG
LAYLPYDQVERAIKEKKLIRVLDKFTPDLPGYHLYYPHRRHAGSAFSLFIDRLKYKGAV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1787589, Length=299, Percent_Identity=100, Blast_Score=602, Evalue=1e-174,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=33.2191780821918, Blast_Score=200, Evalue=9e-53,
Organism=Escherichia coli, GI1786401, Length=288, Percent_Identity=28.8194444444444, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1789639, Length=274, Percent_Identity=28.1021897810219, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI145693193, Length=299, Percent_Identity=28.0936454849498, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI87081978, Length=266, Percent_Identity=24.812030075188, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1789440, Length=272, Percent_Identity=23.5294117647059, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786448, Length=291, Percent_Identity=25.7731958762887, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI145693105, Length=195, Percent_Identity=25.6410256410256, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI2367136, Length=123, Percent_Identity=35.7723577235772, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787879, Length=94, Percent_Identity=43.6170212765958, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788748, Length=122, Percent_Identity=32.7868852459016, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788706, Length=248, Percent_Identity=27.4193548387097, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI157672245, Length=116, Percent_Identity=34.4827586206897, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1788297, Length=250, Percent_Identity=26.8, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790208, Length=194, Percent_Identity=29.3814432989691, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): YCJZ_ECOLI (P77333)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   C64882
- RefSeq:   AP_001956.1
- RefSeq:   NP_415844.1
- ProteinModelPortal:   P77333
- SMR:   P77333
- DIP:   DIP-11617N
- STRING:   P77333
- EnsemblBacteria:   EBESCT00000004126
- EnsemblBacteria:   EBESCT00000016938
- GeneID:   945930
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW1321
- KEGG:   eco:b1328
- EchoBASE:   EB3682
- EcoGene:   EG13923
- eggNOG:   COG0583
- GeneTree:   EBGT00070000031706
- HOGENOM:   HBG685425
- OMA:   MRIGPDI
- ProtClustDB:   CLSK880103
- BioCyc:   EcoCyc:G6664-MONOMER
- Genevestigator:   P77333
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00039

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate

EC number: NA

Molecular weight: Translated: 33482; Mature: 33482

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKREEIADLMAFVVVAEERSFTRAAARLSMAQSALSQIVRRIEERLGLRLLTRTTRSVVP
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCC
TEAGEHLLSVLGPMLHDIDSAMASLSDLQNRPSGTIRITTVEHAAKTILLPAMRTFLKSH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCC
PEIDIQLTIDYGLTDVVSERFDAGVRLGGEMDKDMIAIRIGPDIPMAIVGSPDYFSRRSV
CCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEECCCCHHCCCCC
PTSVSQLIDHQAINLYLPTSGTANRWRLIRGGREVRVRMEGQLLLNTIDLIIDAAIDGHG
CHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHCCCCCC
LAYLPYDQVERAIKEKKLIRVLDKFTPDLPGYHLYYPHRRHAGSAFSLFIDRLKYKGAV
EEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKREEIADLMAFVVVAEERSFTRAAARLSMAQSALSQIVRRIEERLGLRLLTRTTRSVVP
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCC
TEAGEHLLSVLGPMLHDIDSAMASLSDLQNRPSGTIRITTVEHAAKTILLPAMRTFLKSH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHCC
PEIDIQLTIDYGLTDVVSERFDAGVRLGGEMDKDMIAIRIGPDIPMAIVGSPDYFSRRSV
CCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEECCCCHHCCCCC
PTSVSQLIDHQAINLYLPTSGTANRWRLIRGGREVRVRMEGQLLLNTIDLIIDAAIDGHG
CHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHCCCCCC
LAYLPYDQVERAIKEKKLIRVLDKFTPDLPGYHLYYPHRRHAGSAFSLFIDRLKYKGAV
EEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503