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The map label for this gene is ycjQ

Identifier: 157160824

GI number: 157160824

Start: 1422413

End: 1423465

Strand: Direct

Name: ycjQ

Synonym: EcHS_A1428

Alternate gene names: 157160824

Gene position: 1422413-1423465 (Clockwise)

Preceding gene: 157160823

Following gene: 157160825

Centisome position: 30.63

GC content: 55.75

Gene sequence:

>1053_bases
ATGAAAAAGTTAGTAGCCACAGCACCGCGTGTTGCTGCGCTGGTTGAGTATGAAGATCGGGCGATTTTAGCTAATGAAGT
GAAGATCCGCGTGCGTTTCGGCGCACCGAAACACGGAACGGAAGTGGTCGACTTCCGCGCCGCCAGCCCGTTTATTGATG
AAGACTTTAACGGCGAATGGCAGATGTTCACTCCGCGTCCGGCAGATGCGCCGCGCGGCATTGAGTTTGGCAAATTCCAG
CTTGGCAACATGGTGGTTGGCGACATTATCGAGTGCGGCAGCGACGTTACCGACTACGCGGTGGGCGACAGCGTATGCGG
CTACGGCCCGCTCTCCGAGACGGTCATCATTAACGCAGTGAATAACTACAAGCTGCGCAAAATGCCGCAAGGCAGCTCCT
GGAAAAACGCCGTCTGCTACGACCCGGCGCAGTTTGCCATGAGCGGCGTGCGCGATGCCAACGTGCGCGTAGGGGATTTT
GTGGTGGTGGTAGGGCTTGGCGCAATCGGTCAAATTGCCATCCAACTGGCTAAACGCGCTGGCGCTTCTGTGGTGATTGG
CGTCGATCCTATCGCCCATCGCTGTGATATTGCCCGTCGCCACGGCGCGGATTTCTGCCTTAACCCCATCGGCACTGATG
TAGGTAAAGAGATCAAAACGCTGACCGGCAAGCAGGGTGCCGATGTGATTATCGAAACCAGCGGCTACGCCGACGCGCTG
CAATCGGCGCTCCGCGGTCTGGCTTATGGCGGCACCATCTCCTATGTCGCGTTTGCCAAGCCGTTTGCCGAAGGTTTTAA
CCTCGGACGCGAAGCGCATTTCAATAACGCCAAAATTGTCTTCTCTCGCGCGTGCAGCGAACCGAACCCGGATTATCCGC
GCTGGAGCCGCAAGCGTATTGAAGAAACCTGTTGGGAACTGCTGATGAACGGTTATCTCAATTGCGAAGATTTAATCGAC
CCGGTGGTGACCTTTGCCAATAGCCCGGAAAGCTATATGCAGTATGTCGACCAGCATCCGGAACAGAGCATCAAAATGGG
CGTTACGTTTTAA

Upstream 100 bases:

>100_bases
GGTGATTATGTATGCGCTTTCGGAACGTTTTATTAAGAGTGGTTTGACCGCCGGTGGCGTGAAGGGCTAAAGCGGCCAGT
TTCTTTACAAGGAGTTTTAA

Downstream 100 bases:

>100_bases
TTCAAAGGAATGAAAAAAATGAAAATCGGCACACAGAATCAGGCGTTCTTTCCGGAAAACATTCTGGAGAAATTTCGTTA
TATCAAAGAGATGGGCTTCG

Product: zinc-binding dehydrogenase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVDFRAASPFIDEDFNGEWQMFTPRPADAPRGIEFGKFQ
LGNMVVGDIIECGSDVTDYAVGDSVCGYGPLSETVIINAVNNYKLRKMPQGSSWKNAVCYDPAQFAMSGVRDANVRVGDF
VVVVGLGAIGQIAIQLAKRAGASVVIGVDPIAHRCDIARRHGADFCLNPIGTDVGKEIKTLTGKQGADVIIETSGYADAL
QSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNNAKIVFSRACSEPNPDYPRWSRKRIEETCWELLMNGYLNCEDLID
PVVTFANSPESYMQYVDQHPEQSIKMGVTF

Sequences:

>Translated_350_residues
MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVDFRAASPFIDEDFNGEWQMFTPRPADAPRGIEFGKFQ
LGNMVVGDIIECGSDVTDYAVGDSVCGYGPLSETVIINAVNNYKLRKMPQGSSWKNAVCYDPAQFAMSGVRDANVRVGDF
VVVVGLGAIGQIAIQLAKRAGASVVIGVDPIAHRCDIARRHGADFCLNPIGTDVGKEIKTLTGKQGADVIIETSGYADAL
QSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNNAKIVFSRACSEPNPDYPRWSRKRIEETCWELLMNGYLNCEDLID
PVVTFANSPESYMQYVDQHPEQSIKMGVTF
>Mature_350_residues
MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVDFRAASPFIDEDFNGEWQMFTPRPADAPRGIEFGKFQ
LGNMVVGDIIECGSDVTDYAVGDSVCGYGPLSETVIINAVNNYKLRKMPQGSSWKNAVCYDPAQFAMSGVRDANVRVGDF
VVVVGLGAIGQIAIQLAKRAGASVVIGVDPIAHRCDIARRHGADFCLNPIGTDVGKEIKTLTGKQGADVIIETSGYADAL
QSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNNAKIVFSRACSEPNPDYPRWSRKRIEETCWELLMNGYLNCEDLID
PVVTFANSPESYMQYVDQHPEQSIKMGVTF

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1787572, Length=350, Percent_Identity=100, Blast_Score=725, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17562876, Length=154, Percent_Identity=32.4675324675325, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323099, Length=138, Percent_Identity=31.8840579710145, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322619, Length=216, Percent_Identity=27.3148148148148, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319955, Length=216, Percent_Identity=27.3148148148148, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YCJQ_ECOLI (P76043)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   D64880
- RefSeq:   AP_001939.1
- RefSeq:   NP_415829.1
- ProteinModelPortal:   P76043
- SMR:   P76043
- DIP:   DIP-11608N
- STRING:   P76043
- EnsemblBacteria:   EBESCT00000001978
- EnsemblBacteria:   EBESCT00000017285
- GeneID:   945971
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW1306
- KEGG:   eco:b1313
- EchoBASE:   EB3673
- EcoGene:   EG13914
- eggNOG:   COG1063
- GeneTree:   EBGT00050000008812
- HOGENOM:   HBG467788
- OMA:   HRCEIAR
- ProtClustDB:   CLSK880115
- BioCyc:   EcoCyc:G6651-MONOMER
- Genevestigator:   P76043
- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR11695

Pfam domain/function: PF00107 ADH_zinc_N; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 38217; Mature: 38217

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVDFRAASPFIDEDFNGEW
CCCCHHCCCHHHEEEEECCCEEEEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCE
QMFTPRPADAPRGIEFGKFQLGNMVVGDIIECGSDVTDYAVGDSVCGYGPLSETVIINAV
EEECCCCCCCCCCCCCCCEEECCCHHHHHHHCCCCCHHHHCCCCCCCCCCCCCEEEEEEC
NNYKLRKMPQGSSWKNAVCYDPAQFAMSGVRDANVRVGDFVVVVGLGAIGQIAIQLAKRA
CCCEEEECCCCCCCCCCEEECHHHHHHHCCCCCCCEECCEEEEEECCHHHHHHHHHHHHC
GASVVIGVDPIAHRCDIARRHGADFCLNPIGTDVGKEIKTLTGKQGADVIIETSGYADAL
CCEEEEECCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHCCCCCCCEEEECCCHHHHH
QSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNNAKIVFSRACSEPNPDYPRWSRKRI
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHH
EETCWELLMNGYLNCEDLIDPVVTFANSPESYMQYVDQHPEQSIKMGVTF
HHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHCCCCCC
>Mature Secondary Structure
MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVDFRAASPFIDEDFNGEW
CCCCHHCCCHHHEEEEECCCEEEEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCE
QMFTPRPADAPRGIEFGKFQLGNMVVGDIIECGSDVTDYAVGDSVCGYGPLSETVIINAV
EEECCCCCCCCCCCCCCCEEECCCHHHHHHHCCCCCHHHHCCCCCCCCCCCCCEEEEEEC
NNYKLRKMPQGSSWKNAVCYDPAQFAMSGVRDANVRVGDFVVVVGLGAIGQIAIQLAKRA
CCCEEEECCCCCCCCCCEEECHHHHHHHCCCCCCCEECCEEEEEECCHHHHHHHHHHHHC
GASVVIGVDPIAHRCDIARRHGADFCLNPIGTDVGKEIKTLTGKQGADVIIETSGYADAL
CCEEEEECCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHCCCCCCCEEEECCCHHHHH
QSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNNAKIVFSRACSEPNPDYPRWSRKRI
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHH
EETCWELLMNGYLNCEDLIDPVVTFANSPESYMQYVDQHPEQSIKMGVTF
HHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503