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The map label for this gene is yciT [H]

Identifier: 157160792

GI number: 157160792

Start: 1391159

End: 1391908

Strand: Reverse

Name: yciT [H]

Synonym: EcHS_A1396

Alternate gene names: 157160792

Gene position: 1391908-1391159 (Counterclockwise)

Preceding gene: 157160793

Following gene: 157160791

Centisome position: 29.98

GC content: 48.93

Gene sequence:

>750_bases
ATGAATTCCCGACAACAAACTATTCTACAGATGGTCATTGACCAGGGTCAGGTTAGCGTAACCGATCTGGCAAAAGCCAC
TGGAGTTTCTGAAGTTACCATTCGCCAGGATCTCAACACACTCGAAAAACTGAGTTACCTCCGCCGTGCACATGGCTTTG
CTGTTTCGCTTGATAGTGATGACGTCGAAACCCGTATGATGAGCAACTATACGCTGAAGCGTGAACTCGCCGAGTTTGCC
GCGTCGCTGGTTCAACCGGGCGAAACCATCTTTATCGAAAATGGCAGCAGCAATGCCCTACTCGCCCGGACTCTGGGCGA
GCAGAAGAAAAATGTCACTATCATCACGGTCAGCAGCTACATCGCGCATTTGCTGAAAGACGCGCCTTGTGAAGTTATTT
TGCTCGGTGGCGTGTATCAGAAAAAAAGCGAAAGTATGGTTGGCCCTTTGACACGCCAGTGCATCCAACAGGTGCATTTC
AGCAAAGCATTTATTGGTATTGATGGCTGGCAACCTGAAACTGGATTTACCGGTCGCGATATGATGCGTACCGATGTGGT
CAATGCCGTGCTGGAAAAAGAGTGCGAAGCGATAGTCCTGACTGACAGCTCGAAATTTGGTGCTGTACATTCATACTCCA
TCGGTCCCGTTGAGCGATTCAATCGCGTGATTACCGATTCGAAAATACGCGCCAGCGATCTGATGCATCTTGAGCACAGT
AAACTCACCGTTCACGTCGTTGACATTTAA

Upstream 100 bases:

>100_bases
GGGAGATTTAACAATCGTGCCTTCAGGTTTTCCTATTTGAGGATGCCCGGCGCGTCAGTATTTTTTTATTAAGTATTATA
ACGTTATAAGAATTACAGCG

Downstream 100 bases:

>100_bases
CCATTTCCCTTCTCTACGGATGATTTGCAGTTTGGCAAATCATCCGCTCTAAGATGATTCCTGGTTGATAATTAAGACTA
TTTACCTGTTATTAACACTC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MNSRQQTILQMVIDQGQVSVTDLAKATGVSEVTIRQDLNTLEKLSYLRRAHGFAVSLDSDDVETRMMSNYTLKRELAEFA
ASLVQPGETIFIENGSSNALLARTLGEQKKNVTIITVSSYIAHLLKDAPCEVILLGGVYQKKSESMVGPLTRQCIQQVHF
SKAFIGIDGWQPETGFTGRDMMRTDVVNAVLEKECEAIVLTDSSKFGAVHSYSIGPVERFNRVITDSKIRASDLMHLEHS
KLTVHVVDI

Sequences:

>Translated_249_residues
MNSRQQTILQMVIDQGQVSVTDLAKATGVSEVTIRQDLNTLEKLSYLRRAHGFAVSLDSDDVETRMMSNYTLKRELAEFA
ASLVQPGETIFIENGSSNALLARTLGEQKKNVTIITVSSYIAHLLKDAPCEVILLGGVYQKKSESMVGPLTRQCIQQVHF
SKAFIGIDGWQPETGFTGRDMMRTDVVNAVLEKECEAIVLTDSSKFGAVHSYSIGPVERFNRVITDSKIRASDLMHLEHS
KLTVHVVDI
>Mature_249_residues
MNSRQQTILQMVIDQGQVSVTDLAKATGVSEVTIRQDLNTLEKLSYLRRAHGFAVSLDSDDVETRMMSNYTLKRELAEFA
ASLVQPGETIFIENGSSNALLARTLGEQKKNVTIITVSSYIAHLLKDAPCEVILLGGVYQKKSESMVGPLTRQCIQQVHF
SKAFIGIDGWQPETGFTGRDMMRTDVVNAVLEKECEAIVLTDSSKFGAVHSYSIGPVERFNRVITDSKIRASDLMHLEHS
KLTVHVVDI

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787540, Length=249, Percent_Identity=99.5983935742972, Blast_Score=515, Evalue=1e-147,
Organism=Escherichia coli, GI1789519, Length=251, Percent_Identity=32.2709163346614, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789059, Length=247, Percent_Identity=30.3643724696356, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI226510968, Length=230, Percent_Identity=29.1304347826087, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1789829, Length=229, Percent_Identity=27.9475982532751, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1790753, Length=253, Percent_Identity=26.8774703557312, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI87082344, Length=229, Percent_Identity=25.3275109170306, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789170, Length=240, Percent_Identity=25.4166666666667, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790635, Length=252, Percent_Identity=27.3809523809524, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788069, Length=228, Percent_Identity=25.8771929824561, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787063, Length=233, Percent_Identity=26.6094420600858, Blast_Score=71, Evalue=6e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27589; Mature: 27589

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSRQQTILQMVIDQGQVSVTDLAKATGVSEVTIRQDLNTLEKLSYLRRAHGFAVSLDSD
CCHHHHHHHHHHHHCCCEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
DVETRMMSNYTLKRELAEFAASLVQPGETIFIENGSSNALLARTLGEQKKNVTIITVSSY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHHCCCCCCEEEEEHHHH
IAHLLKDAPCEVILLGGVYQKKSESMVGPLTRQCIQQVHFSKAFIGIDGWQPETGFTGRD
HHHHHCCCCCCEEEECCCHHCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHH
MMRTDVVNAVLEKECEAIVLTDSSKFGAVHSYSIGPVERFNRVITDSKIRASDLMHLEHS
HHHHHHHHHHHHCCCCEEEEECCCCCCCEEECCCCHHHHHHHHHCCCCCCHHHHHHEECC
KLTVHVVDI
EEEEEEEEC
>Mature Secondary Structure
MNSRQQTILQMVIDQGQVSVTDLAKATGVSEVTIRQDLNTLEKLSYLRRAHGFAVSLDSD
CCHHHHHHHHHHHHCCCEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
DVETRMMSNYTLKRELAEFAASLVQPGETIFIENGSSNALLARTLGEQKKNVTIITVSSY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEHHHHHCCCCCCEEEEEHHHH
IAHLLKDAPCEVILLGGVYQKKSESMVGPLTRQCIQQVHFSKAFIGIDGWQPETGFTGRD
HHHHHCCCCCCEEEECCCHHCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCCHH
MMRTDVVNAVLEKECEAIVLTDSSKFGAVHSYSIGPVERFNRVITDSKIRASDLMHLEHS
HHHHHHHHHHHHCCCCEEEEECCCCCCCEEECCCCHHHHHHHHHCCCCCCHHHHHHEECC
KLTVHVVDI
EEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]