Click here to switch to the map view.

The map label for this gene is fiu [H]

Identifier: 157160281

GI number: 157160281

Start: 865853

End: 868135

Strand: Reverse

Name: fiu [H]

Synonym: EcHS_A0860

Alternate gene names: 157160281

Gene position: 868135-865853 (Counterclockwise)

Preceding gene: 157160282

Following gene: 157160280

Centisome position: 18.7

GC content: 53.83

Gene sequence:

>2283_bases
ATGGAAAACAATCGCAATTTCCCTGCCAGACAATTTCATTCGCTCACGTTCTTTGCCGGTCTTTGTATTGGCATCACGCC
TGTGGCTCAGGCACTCGCCGCCGAAGGGCAAACTAACGCGGATGACACGCTGGTTGTCGAAGCATCAACGCCTTCGCTTT
ATGCGCCACAACAATCTGCCGATCCGAAATTCTCGCGTCCGGTAGCGGATACTACCCGCACGATGACGGTAATTTCTGAA
CAAGTGATTAAAGATCAGGGCGCAACCAACCTTACCGACGCGCTCAAAAACGTCCCCGGCGTGGGTGCGTTTTTTGCGGG
TGAGAACGGTAACTCCACCACTGGCGACGCCATTTATATGCGTGGTGCCGATACCTCTAACAGTATTTATATTGATGGCA
TTCGCGATATCGGCAGCGTCTCGCGCGACACCTTCAATACCGAGCAGGTCGAAGTGATTAAAGGGCCGTCCGGCACCGAC
TACGGGCGCAGCGCACCGACAGGCTCGATCAATATGATCAGCAAGCAGCCGCGCAATGATTCCGGCATTGACGCCTCCGC
CAGTATTGGCAGCGCCTGGTTCCGCCGCGGCACGCTGGACGTCAATCAGGTCATTGGTGATACCACCGCGGTGCGCCTGA
ATGTAATGGGCGAAAAAACGCACGATGCCGGACGCGACAAAGTCAAAAATGAGCGTTACGGCGTCGCCCCTTCTGTCGCT
TTTGGCCTTGGTACAGCGAATCGTTTGTATCTTAATTATCTGCATGTCACCCAGCACAACACGCCAGACGGCGGCATTCC
GACCATCGGTTTGCCGGGCTATTCTGCCCCATCTGCGGGAACGGCGGCCCTGAATCATTCCGGAAAAGTTGATACTCATA
ACTTTTACGGCACGGATTCCGATTACGACGATTCGACCACCGACACCGCCACCATGCGTTTTGAGCACGACATCAACGAT
AACACCACCATTCGCAATACTACCCGTTGGTCGCGCGTAAAGCAGGATTACCTGATGACGGCGATTATGGGCGGGGCGTC
GAATATTACTCAGCCCACCAGCGATGTGAATAGCTGGACCTGGTCACGCACGGCGAATACCAAAGATGTGAGTAATAAAA
TTCTCACCAACCAGACCAACCTGACCTCGACGTTCTATACCGGTTCTATCGGTCATGATGTCAGTACCGGCGTGGAATTT
ACCCGTGAAACGCAGACTAACTACGGCGTTAATCCGGTGACGTTACCCGCGGTAAATATTTATCATCCTGACAGCAGCAT
TCATCCCGGCGGCCTGACGCGCAACGGCGCAAACGCCAATGGTCAGACGGATACCTTCGCAATTTACGCCTTTGATACGC
TGCAAATCACCCGTGATTTTGAGCTGAACGGCGGGATCCGTCTGGATAATTATCATACTGAATATGACAGTGCCACCGCC
TGCGGCGGCAGCGGACGCGGTGCCATCACCTGCCCAACTGGTGTGGCAAAAGGTTCTCCGGTCACCACCGTCGACACCGC
CAAGTCGGGCAATCTGATGAACTGGAAAGCCGGGGCGCTGTATCACCTGACGGAAAACGGCAATGTCTATATTAACTATG
CCGTTTCCCAGCAGCCTCCGGGCGGCAACAACTTCGCCCTTGCGCAGTCTGGCAGCGGTAACAGTGCCAACCGCACCGAT
TTTAAACCGCAAAAAGCCAACACCAGCGAGATTGGCACCAAATGGCAGGTTCTGGATAAACGTCTGTTGCTCACCGCCGC
GCTGTTCCGCACTGATATCGAAAATGAAGTTGAGCAAAATGATGACGGAACTTACTCGCAATACGGTAAGAAACGCGTCG
AAGGCTATGAGATATCCGTGGCCGGGAATATCACTCCCGCGTGGCAGGTGATTGGCGGCTATACCCAGCAAAAAGCAACC
ATCAAAAACGGCAAAGATGTTGCCCAGGATGGTTCCTCATCGCTGCCGTATACCCCGGAGCACGCCTTCACCTTATGGAG
CCAATATCAGGCAACCGACGATATCTCTGTTGGCGCGGGCGCACGCTATATCGGCAGTATGCATAAAGGTTCAGACGGCG
CGGTGGGAACGCCAGCGTTTACCGAAGGTTACTGGGTCGCCGATGCCAAACTGGGGTATCGAGTTAATCGCAATCTCGAC
TTCCAGCTAAACGTTTACAACCTGTTTGATACCGATTACGTCGCCTCAATCAACAAGAGCGGCTACCGTTATCACCCGGG
CGAGCCAAGAACCTTCTTGCTCACAGCCAATATGCATTTCTGA

Upstream 100 bases:

>100_bases
GCACGAACACTATCACGGGATTAACAGTGGCATCGCATCCGCAGAGATGCTTTCTTGTGGCAGTGAAAATTTCAACATAT
AAGAAAAAGTCACCTGCAAA

Downstream 100 bases:

>100_bases
ATCAGATGTGGGGCGCAGGCCCCACTTTTTGGAGAAATTGTATGATGTACCACATTCCCGGCGTGTTATCGCCACAGGAC
GTCGCTCGTTTTCGCGAACA

Product: catecholate siderophore receptor Fiu

Products: NA

Alternate protein names: Ferric iron uptake protein; TonB-dependent receptor fiu [H]

Number of amino acids: Translated: 760; Mature: 760

Protein sequence:

>760_residues
MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTLVVEASTPSLYAPQQSADPKFSRPVADTTRTMTVISE
QVIKDQGATNLTDALKNVPGVGAFFAGENGNSTTGDAIYMRGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTD
YGRSAPTGSINMISKQPRNDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGEKTHDAGRDKVKNERYGVAPSVA
FGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSAPSAGTAALNHSGKVDTHNFYGTDSDYDDSTTDTATMRFEHDIND
NTTIRNTTRWSRVKQDYLMTAIMGGASNITQPTSDVNSWTWSRTANTKDVSNKILTNQTNLTSTFYTGSIGHDVSTGVEF
TRETQTNYGVNPVTLPAVNIYHPDSSIHPGGLTRNGANANGQTDTFAIYAFDTLQITRDFELNGGIRLDNYHTEYDSATA
CGGSGRGAITCPTGVAKGSPVTTVDTAKSGNLMNWKAGALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTD
FKPQKANTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQNDDGTYSQYGKKRVEGYEISVAGNITPAWQVIGGYTQQKAT
IKNGKDVAQDGSSSLPYTPEHAFTLWSQYQATDDISVGAGARYIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLD
FQLNVYNLFDTDYVASINKSGYRYHPGEPRTFLLTANMHF

Sequences:

>Translated_760_residues
MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTLVVEASTPSLYAPQQSADPKFSRPVADTTRTMTVISE
QVIKDQGATNLTDALKNVPGVGAFFAGENGNSTTGDAIYMRGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTD
YGRSAPTGSINMISKQPRNDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGEKTHDAGRDKVKNERYGVAPSVA
FGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSAPSAGTAALNHSGKVDTHNFYGTDSDYDDSTTDTATMRFEHDIND
NTTIRNTTRWSRVKQDYLMTAIMGGASNITQPTSDVNSWTWSRTANTKDVSNKILTNQTNLTSTFYTGSIGHDVSTGVEF
TRETQTNYGVNPVTLPAVNIYHPDSSIHPGGLTRNGANANGQTDTFAIYAFDTLQITRDFELNGGIRLDNYHTEYDSATA
CGGSGRGAITCPTGVAKGSPVTTVDTAKSGNLMNWKAGALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTD
FKPQKANTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQNDDGTYSQYGKKRVEGYEISVAGNITPAWQVIGGYTQQKAT
IKNGKDVAQDGSSSLPYTPEHAFTLWSQYQATDDISVGAGARYIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLD
FQLNVYNLFDTDYVASINKSGYRYHPGEPRTFLLTANMHF
>Mature_760_residues
MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTLVVEASTPSLYAPQQSADPKFSRPVADTTRTMTVISE
QVIKDQGATNLTDALKNVPGVGAFFAGENGNSTTGDAIYMRGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTD
YGRSAPTGSINMISKQPRNDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGEKTHDAGRDKVKNERYGVAPSVA
FGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSAPSAGTAALNHSGKVDTHNFYGTDSDYDDSTTDTATMRFEHDIND
NTTIRNTTRWSRVKQDYLMTAIMGGASNITQPTSDVNSWTWSRTANTKDVSNKILTNQTNLTSTFYTGSIGHDVSTGVEF
TRETQTNYGVNPVTLPAVNIYHPDSSIHPGGLTRNGANANGQTDTFAIYAFDTLQITRDFELNGGIRLDNYHTEYDSATA
CGGSGRGAITCPTGVAKGSPVTTVDTAKSGNLMNWKAGALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTD
FKPQKANTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQNDDGTYSQYGKKRVEGYEISVAGNITPAWQVIGGYTQQKAT
IKNGKDVAQDGSSSLPYTPEHAFTLWSQYQATDDISVGAGARYIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLD
FQLNVYNLFDTDYVASINKSGYRYHPGEPRTFLLTANMHF

Specific function: Involved in the active transport across the outer membrane of iron complexed with catecholate siderophores such as dihydroxybenzoylserine and dihydroxybenzoate. It derives its energy for transport by interacting with the trans-periplasmic membrane protein

COG id: COG4774

COG function: function code P; Outer membrane receptor for monomeric catechols

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1787024, Length=760, Percent_Identity=100, Blast_Score=1565, Evalue=0.0,
Organism=Escherichia coli, GI1786344, Length=818, Percent_Identity=24.5721271393643, Blast_Score=123, Evalue=6e-29,
Organism=Escherichia coli, GI1790405, Length=207, Percent_Identity=29.951690821256, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1787723, Length=256, Percent_Identity=28.515625, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 81961; Mature: 81961

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTLVVEASTPSLYAPQQSA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEECCCCCC
DPKFSRPVADTTRTMTVISEQVIKDQGATNLTDALKNVPGVGAFFAGENGNSTTGDAIYM
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCEEEE
RGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTDYGRSAPTGSINMISKQPRND
ECCCCCCCEEEECCHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCCC
SGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGEKTHDAGRDKVKNERYGVAPSVA
CCCCCCCCCCHHHHHCCCCCHHHHHCCCEEEEEEEECCCCCCCCHHHHCCCCCCCCCHHE
FGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSAPSAGTAALNHSGKVDTHNFYGTDS
ECCCCCCEEEEEEEEEEECCCCCCCCCEECCCCCCCCCCCCEEECCCCCCCCCCCCCCCC
DYDDSTTDTATMRFEHDINDNTTIRNTTRWSRVKQDYLMTAIMGGASNITQPTSDVNSWT
CCCCCCCCEEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
WSRTANTKDVSNKILTNQTNLTSTFYTGSIGHDVSTGVEFTRETQTNYGVNPVTLPAVNI
EECCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCEEEEEEEE
YHPDSSIHPGGLTRNGANANGQTDTFAIYAFDTLQITRDFELNGGIRLDNYHTEYDSATA
ECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEEEEEECCCCEEECCCCCCCCCCCC
CGGSGRGAITCPTGVAKGSPVTTVDTAKSGNLMNWKAGALYHLTENGNVYINYAVSQQPP
CCCCCCCEEECCCCCCCCCCEEEEECCCCCCEEEECCCEEEEEECCCCEEEEEEECCCCC
GGNNFALAQSGSGNSANRTDFKPQKANTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQN
CCCCEEEEECCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DDGTYSQYGKKRVEGYEISVAGNITPAWQVIGGYTQQKATIKNGKDVAQDGSSSLPYTPE
CCCCHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCCCEECCCCCHHHCCCCCCCCCCCC
HAFTLWSQYQATDDISVGAGARYIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLD
HHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEEEEECEECEEECCCEE
FQLNVYNLFDTDYVASINKSGYRYHPGEPRTFLLTANMHF
EEEEEEEECCCCHHHHCCCCCCEECCCCCEEEEEEECCCC
>Mature Secondary Structure
MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTLVVEASTPSLYAPQQSA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEECCCCCC
DPKFSRPVADTTRTMTVISEQVIKDQGATNLTDALKNVPGVGAFFAGENGNSTTGDAIYM
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCEEEE
RGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTDYGRSAPTGSINMISKQPRND
ECCCCCCCEEEECCHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCCC
SGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGEKTHDAGRDKVKNERYGVAPSVA
CCCCCCCCCCHHHHHCCCCCHHHHHCCCEEEEEEEECCCCCCCCHHHHCCCCCCCCCHHE
FGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSAPSAGTAALNHSGKVDTHNFYGTDS
ECCCCCCEEEEEEEEEEECCCCCCCCCEECCCCCCCCCCCCEEECCCCCCCCCCCCCCCC
DYDDSTTDTATMRFEHDINDNTTIRNTTRWSRVKQDYLMTAIMGGASNITQPTSDVNSWT
CCCCCCCCEEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
WSRTANTKDVSNKILTNQTNLTSTFYTGSIGHDVSTGVEFTRETQTNYGVNPVTLPAVNI
EECCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCEEEEEEEE
YHPDSSIHPGGLTRNGANANGQTDTFAIYAFDTLQITRDFELNGGIRLDNYHTEYDSATA
ECCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEEEEEECCCCEEECCCCCCCCCCCC
CGGSGRGAITCPTGVAKGSPVTTVDTAKSGNLMNWKAGALYHLTENGNVYINYAVSQQPP
CCCCCCCEEECCCCCCCCCCEEEEECCCCCCEEEECCCEEEEEECCCCEEEEEEECCCCC
GGNNFALAQSGSGNSANRTDFKPQKANTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQN
CCCCEEEEECCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
DDGTYSQYGKKRVEGYEISVAGNITPAWQVIGGYTQQKATIKNGKDVAQDGSSSLPYTPE
CCCCHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCCCEECCCCCHHHCCCCCCCCCCCC
HAFTLWSQYQATDDISVGAGARYIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLD
HHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCEEEEECEECEEECCCEE
FQLNVYNLFDTDYVASINKSGYRYHPGEPRTFLLTANMHF
EEEEEEEECCCCHHHHCCCCCCEECCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]