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The map label for this gene is ybiH

Identifier: 157160271

GI number: 157160271

Start: 856576

End: 857247

Strand: Reverse

Name: ybiH

Synonym: EcHS_A0850

Alternate gene names: 157160271

Gene position: 857247-856576 (Counterclockwise)

Preceding gene: 157160273

Following gene: 157160270

Centisome position: 18.46

GC content: 54.17

Gene sequence:

>672_bases
ATGAATAATCCTGCCATGACAATCAAGGGTGAACAGGCGAAAAAACAGCTGATTGCTGCCGCACTGGCGCAGTTTGGTGA
ATATGGAATGAACGCCACCACTCGCGAGATAGCCGCCCAGGCCGGGCAGAATATCGCTGCCATCACCTACTACTTCGGTT
CGAAAGAAGATTTGTACCTCGCCTGCGCCCAGTGGATTGCCGATTTTATTGGCGAGCAGTTCCGTCCGCATGCCGAGGAA
GCCGAACGCTTGTTCGCGCAACCACAGCCTGATCGGGCTGCCATCCGTGAACTGATCCTTCGCGCCTGCAGGAACATGAT
TAAGCTGCTCACCCAGGATGACACCGTCAACCTCAGCAAGTTTATCTCCCGTGAGCAGCTCTCTCCCACGGCAGCCTACC
ACCTGGTGCACGAACAGGTGATTAGTCCGCTACACAGCCACCTGACACGCCTGATTGCCGCCTGGACCGGCTGCGACGCC
AATGACACCCGCATGATCCTTCATACCCATGCGTTGATTGGTGAGATTCTGGCGTTCCGTCTTGGCAAAGAAACAATTCT
GTTACGTACCGGCTGGACCGCGTTCGATGAAGAAAAGACCGAACTGATCAACCAGACGGTGACCTGTCATATCGACCTGA
TTTTGCAAGGATTATCGCAAAGGAGTTTGTAG

Upstream 100 bases:

>100_bases
ATCCCTGTGACTGGCGTTGCTAAAATTCTTAGCCATACTGGACAACTCCCCTATGGAGTCATAATCTTAATCAATCATTT
GATTAAGAATGGACTGTGCG

Downstream 100 bases:

>100_bases
TGATGAAAAAACCTGTCGTGATCGGATTGGCGGTAGTGGTACTTGCCGCCGTGGTTGCCGGAGGCTACTGGTGGTATCAA
AGCCGCCAGGATAACGGCCT

Product: putative DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MNNPAMTIKGEQAKKQLIAAALAQFGEYGMNATTREIAAQAGQNIAAITYYFGSKEDLYLACAQWIADFIGEQFRPHAEE
AERLFAQPQPDRAAIRELILRACRNMIKLLTQDDTVNLSKFISREQLSPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDA
NDTRMILHTHALIGEILAFRLGKETILLRTGWTAFDEEKTELINQTVTCHIDLILQGLSQRSL

Sequences:

>Translated_223_residues
MNNPAMTIKGEQAKKQLIAAALAQFGEYGMNATTREIAAQAGQNIAAITYYFGSKEDLYLACAQWIADFIGEQFRPHAEE
AERLFAQPQPDRAAIRELILRACRNMIKLLTQDDTVNLSKFISREQLSPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDA
NDTRMILHTHALIGEILAFRLGKETILLRTGWTAFDEEKTELINQTVTCHIDLILQGLSQRSL
>Mature_223_residues
MNNPAMTIKGEQAKKQLIAAALAQFGEYGMNATTREIAAQAGQNIAAITYYFGSKEDLYLACAQWIADFIGEQFRPHAEE
AERLFAQPQPDRAAIRELILRACRNMIKLLTQDDTVNLSKFISREQLSPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDA
NDTRMILHTHALIGEILAFRLGKETILLRTGWTAFDEEKTELINQTVTCHIDLILQGLSQRSL

Specific function: Unknown

COG id: COG1309

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI87081783, Length=223, Percent_Identity=100, Blast_Score=462, Evalue=1e-131,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): YBIH_ECOLI (P0ACU0)

Other databases:

- EMBL:   L02123
- EMBL:   U00096
- EMBL:   AP009048
- RefSeq:   AP_001427.1
- RefSeq:   NP_415317.4
- ProteinModelPortal:   P0ACU0
- SMR:   P0ACU0
- STRING:   P0ACU0
- EnsemblBacteria:   EBESCT00000001856
- EnsemblBacteria:   EBESCT00000015471
- GeneID:   945421
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW0780
- KEGG:   eco:b0796
- EchoBASE:   EB2306
- EcoGene:   EG12406
- eggNOG:   COG1309
- GeneTree:   EBGT00050000011824
- HOGENOM:   HBG416446
- OMA:   FRMARET
- ProtClustDB:   PRK11552
- BioCyc:   EcoCyc:EG12406-MONOMER
- Genevestigator:   P0ACU0
- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- InterPro:   IPR015292
- Gene3D:   G3DSA:1.10.357.10
- PRINTS:   PR00455

Pfam domain/function: PF09209 DUF1956; PF00440 TetR_N; SSF46689 Homeodomain_like; SSF48498 TetR_like_C

EC number: NA

Molecular weight: Translated: 25017; Mature: 25017

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01081 HTH_TETR_1; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNPAMTIKGEQAKKQLIAAALAQFGEYGMNATTREIAAQAGQNIAAITYYFGSKEDLYL
CCCCCEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEEECCCCHHHH
ACAQWIADFIGEQFRPHAEEAERLFAQPQPDRAAIRELILRACRNMIKLLTQDDTVNLSK
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
FISREQLSPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDANDTRMILHTHALIGEILAFR
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
LGKETILLRTGWTAFDEEKTELINQTVTCHIDLILQGLSQRSL
HCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNNPAMTIKGEQAKKQLIAAALAQFGEYGMNATTREIAAQAGQNIAAITYYFGSKEDLYL
CCCCCEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEEECCCCHHHH
ACAQWIADFIGEQFRPHAEEAERLFAQPQPDRAAIRELILRACRNMIKLLTQDDTVNLSK
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
FISREQLSPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDANDTRMILHTHALIGEILAFR
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
LGKETILLRTGWTAFDEEKTELINQTVTCHIDLILQGLSQRSL
HCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8037924; 8905232; 9278503