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The map label for this gene is tolR [H]

Identifier: 157160221

GI number: 157160221

Start: 802702

End: 803130

Strand: Direct

Name: tolR [H]

Synonym: EcHS_A0791

Alternate gene names: 157160221

Gene position: 802702-803130 (Clockwise)

Preceding gene: 157160220

Following gene: 157160222

Centisome position: 17.29

GC content: 51.52

Gene sequence:

>429_bases
ATGGCCAGAGCGCGTGGACGAGGTCGTCGCGATCTCAAGTCCGAAATCAACATTGTACCGTTGCTGGACGTACTGCTGGT
GCTGTTGCTGATCTTTATGGCGACAGCGCCCATCATCACCCAGAGCGTGGAGGTCGATCTGCCAGACGCTACTGAATCAC
AGGCGGTGAGCAGTAACGATAATCCGCCAGTGATTGTTGAAGTGTCTGGTATTGGTCAGTACACCGTGGTGTTTGAGAAA
GATCGCCTGGAGCGTTTACCACCAGAGCAGGTGGTGGCGGAAGTGTCCAGCCGTTTCAAGGCCAACCCGAAAACGGTCTT
TCTGATCGGTGGCGCAAAAGATGTGCCTTACGATGAAATAATTAAAGCACTGAACTTGTTACATAGTGCGGGTGTGAAAT
CGGTTGGTTTAATGACGCAGCCTATCTAA

Upstream 100 bases:

>100_bases
AAACAAACTGGAACTGAATTACGACAACTTTATGGAAGAGTTTACCGCGATTCTGCACCGCCAGGCGTTTACCGTTAGCG
AGAGCAACAAGGGGTAAGCC

Downstream 100 bases:

>100_bases
ACATCTGCGTTTCCCTTGCTTGAAAGAGAGCGGGTAACAGGCGAACAGTTTTTGGAAACCGAGAGTGTCAAAGGCAACCG
AACAAAACGACAAGCTCAAG

Product: colicin uptake protein TolR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPDATESQAVSSNDNPPVIVEVSGIGQYTVVFEK
DRLERLPPEQVVAEVSSRFKANPKTVFLIGGAKDVPYDEIIKALNLLHSAGVKSVGLMTQPI

Sequences:

>Translated_142_residues
MARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPDATESQAVSSNDNPPVIVEVSGIGQYTVVFEK
DRLERLPPEQVVAEVSSRFKANPKTVFLIGGAKDVPYDEIIKALNLLHSAGVKSVGLMTQPI
>Mature_141_residues
ARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPDATESQAVSSNDNPPVIVEVSGIGQYTVVFEKD
RLERLPPEQVVAEVSSRFKANPKTVFLIGGAKDVPYDEIIKALNLLHSAGVKSVGLMTQPI

Specific function: Involved In The Tonb-Independent Uptake Of Group A Colicins (Colicins A, E1, E2, E3, And K). [C]

COG id: COG0848

COG function: function code U; Biopolymer transport protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbD/tolR family [H]

Homologues:

Organism=Escherichia coli, GI1786959, Length=142, Percent_Identity=99.2957746478873, Blast_Score=280, Evalue=3e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014168
- InterPro:   IPR003400 [H]

Pfam domain/function: PF02472 ExbD [H]

EC number: NA

Molecular weight: Translated: 15431; Mature: 15300

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPDATESQAVSSND
CCCCCCCCCHHHHHHCCEECHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCC
NPPVIVEVSGIGQYTVVFEKDRLERLPPEQVVAEVSSRFKANPKTVFLIGGAKDVPYDEI
CCCEEEEECCCCEEEEEEECCHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHH
IKALNLLHSAGVKSVGLMTQPI
HHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
ARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVEVDLPDATESQAVSSND
CCCCCCCCHHHHHHCCEECHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCC
NPPVIVEVSGIGQYTVVFEKDRLERLPPEQVVAEVSSRFKANPKTVFLIGGAKDVPYDEI
CCCEEEEECCCCEEEEEEECCHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHH
IKALNLLHSAGVKSVGLMTQPI
HHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]