| Definition | Escherichia coli HS, complete genome. |
|---|---|
| Accession | NC_009800 |
| Length | 4,643,538 |
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The map label for this gene is hrsA [H]
Identifier: 157160210
GI number: 157160210
Start: 792120
End: 794036
Strand: Direct
Name: hrsA [H]
Synonym: EcHS_A0778
Alternate gene names: 157160210
Gene position: 792120-794036 (Clockwise)
Preceding gene: 157160208
Following gene: 157160213
Centisome position: 17.06
GC content: 54.88
Gene sequence:
>1917_bases ATGAATCTGACGACTCTGACCCACCGCGATGCGTTGTGTCTGAATGCGCGCTTTACCAGCCGTGAAGAGGCCATCCACGT GTTGACTCAACGTCTTGCTGCTCTGGGGAAAATTTCCAGTACTGAGCAATTTCTGGAAGAAGTGTATCGCCGTGAAAGCC TTGGCCCGACCGCCTTAGGTGAAGGGTTGGCTGTGCCGCATGGCAAAACTGCTGCGGTAAAAGAAGCGGCGTTTGCGGTC GCCACACTCAGCGAGCCGCTTCAGTGGGAAGGCGTTGATGGCCCGGAAGCAGTTGATTTAGTGGTGCTGCTGGCGATTCC CCCCAATGAAGCGGGTACTACGCATATGCAACTGCTGACAGCGCTGACCACGCGCCTTGCGGATGATGAGATTCGGGCGC GTATACAGTCGGCGACGACGCCTGATGAGTTGCTCTCGGCGCTGGATGACAAGGGAGGCACGCAACCTTCTGCCTCTTTT TCCAACGCGCCAACTATCGTCTGCGTAACGGCCTGTCCGGCGGGTATTGCTCACACCTATATGGCTGCGGAATATCTGGA AAAAGCCGGACGCAAACTCGGCGTAAATGTTTACGTTGAAAAACAAGGCGCTAACGGCATTGAAGGGCGTTTAACGGCGG ATCAACTCAATAGTGCAACCGCCTGTATTTTTGCGGCTGAAGTCGCCATCAAGGAGAGTGAGCGTTTTAATGGCATTCCC GCGCTTTCAGTGCCTGTTGCCGAGCCGATTCGCCATGCAGAAGCGTTGATCCAACAAGCGCTTACCCTCAAGCGTAGCGA TGAGACGCGTACCGTACAGCAAGATACGCAACCGGTGAAAAGTGTCAAAACGGAGCTGAAACAGGCACTGTTGAGCGGAA TCTCTTTTGCCGTACCGTTGATTGTCGCGGGGGGCACGGTGCTGGCGGTCGCGGTATTACTGTCGCAAATCTTCGGGCTA CAAGATCTGTTTAATGAAGAAAACTCCTGGCTGTGGATGTACCGCAAGCTGGGCGGCGGGCTGCTCGGAATTTTGATGGT ACCGGTGCTCGCGGCCTATACCGCCTATTCTCTGGCAGATAAACCGGCGTTAGCGCCAGGCTTTGCGGCTGGACTTGCCG CCAACATGATCGGCTCCGGGTTTCTCGGCGCGGTCGTTGGCGGATTGATAGCCGGTTACTTGATGCGCTGGGTGAAAAAT CACTTGCGTCTTAGCAGTAAATTCAATGGATTCCTGACTTTTTATCTCTACCCGGTGCTCGGTACGTTGGGAGCGGGCAG TCTGATGCTGTTTGTGGTGGGGGAACCTGTCGCCTGGATCAATAACTCGCTTACCGCCTGGCTGAACGGTCTGTCAGGAA GTAACGCGCTGTTGCTGGGTGCCATTCTCGGTTTTATGTGTTCCTTTGACCTTGGAGGGCCAGTGAATAAAGCCGCTTAT GCATTCTGCCTGGGCGCAATGGCGAACGGCGTTTACGGCCCGTATGCCATTTTCGCCTCCGTCAAAATGGTTTCGGCATT TACCGTAACCGCTTCCACGATGCTCGCACCGCGCCTGTTTAAAGAGTTTGAAATTGAGACCGGGAAATCCACCTGGCTGT TAGGGCTGGCAGGTATTACCGAAGGGGCGATCCCGATGGCGATTGAAGATCCGCTGCGGGTTATTGGTTCGTTTGTGCTG GGCTCTATGGTAACGGGCGCTATTGTCGGTGCGATGAATATCGGCCTTTCGACACCCGGTGCCGGCATTTTCTCGCTCTT TTTACTTCATGATAATGGCGCGGGCGGTGTTATGGCGGCAATTGGCTGGTTTGGCGCGGCATTGGTGGGGGCTGCAATCT CGACTGCAATTCTCCTGATGTGGCGGCGTCACGCGGTTAAGCATGGCAACTATCTGACTGATGGCGTAATGCCATAA
Upstream 100 bases:
>100_bases ACAATACAAATAATTTCAATCAAGTGAAATTGATCACATAATGGTATTGTTTTATCGGGCACGCTGGCGCGACTATAAAA ACGATCAAGTGAGGATCATG
Downstream 100 bases:
>100_bases ACAAAAAGGAAACGACGATGAAAGCAGTATCTCGCGTTCACATCACCCCGCATATGCACTGGGATCGAGAGTGGTATTTC ACCACCGAAGAGTCACGTAT
Product: 2-O-a-mannosyl-D-glycerate specific PTS transporten components IIABC
Products: NA
Alternate protein names: Putative PTS system EIIABC component; Phosphotransferase enzyme IIA component; PTS system EIIA component; Phosphotransferase enzyme IIB component; PTS system EIIB component; Permease IIC component; PTS system EIIC component [H]
Number of amino acids: Translated: 638; Mature: 638
Protein sequence:
>638_residues MNLTTLTHRDALCLNARFTSREEAIHVLTQRLAALGKISSTEQFLEEVYRRESLGPTALGEGLAVPHGKTAAVKEAAFAV ATLSEPLQWEGVDGPEAVDLVVLLAIPPNEAGTTHMQLLTALTTRLADDEIRARIQSATTPDELLSALDDKGGTQPSASF SNAPTIVCVTACPAGIAHTYMAAEYLEKAGRKLGVNVYVEKQGANGIEGRLTADQLNSATACIFAAEVAIKESERFNGIP ALSVPVAEPIRHAEALIQQALTLKRSDETRTVQQDTQPVKSVKTELKQALLSGISFAVPLIVAGGTVLAVAVLLSQIFGL QDLFNEENSWLWMYRKLGGGLLGILMVPVLAAYTAYSLADKPALAPGFAAGLAANMIGSGFLGAVVGGLIAGYLMRWVKN HLRLSSKFNGFLTFYLYPVLGTLGAGSLMLFVVGEPVAWINNSLTAWLNGLSGSNALLLGAILGFMCSFDLGGPVNKAAY AFCLGAMANGVYGPYAIFASVKMVSAFTVTASTMLAPRLFKEFEIETGKSTWLLGLAGITEGAIPMAIEDPLRVIGSFVL GSMVTGAIVGAMNIGLSTPGAGIFSLFLLHDNGAGGVMAAIGWFGAALVGAAISTAILLMWRRHAVKHGNYLTDGVMP
Sequences:
>Translated_638_residues MNLTTLTHRDALCLNARFTSREEAIHVLTQRLAALGKISSTEQFLEEVYRRESLGPTALGEGLAVPHGKTAAVKEAAFAV ATLSEPLQWEGVDGPEAVDLVVLLAIPPNEAGTTHMQLLTALTTRLADDEIRARIQSATTPDELLSALDDKGGTQPSASF SNAPTIVCVTACPAGIAHTYMAAEYLEKAGRKLGVNVYVEKQGANGIEGRLTADQLNSATACIFAAEVAIKESERFNGIP ALSVPVAEPIRHAEALIQQALTLKRSDETRTVQQDTQPVKSVKTELKQALLSGISFAVPLIVAGGTVLAVAVLLSQIFGL QDLFNEENSWLWMYRKLGGGLLGILMVPVLAAYTAYSLADKPALAPGFAAGLAANMIGSGFLGAVVGGLIAGYLMRWVKN HLRLSSKFNGFLTFYLYPVLGTLGAGSLMLFVVGEPVAWINNSLTAWLNGLSGSNALLLGAILGFMCSFDLGGPVNKAAY AFCLGAMANGVYGPYAIFASVKMVSAFTVTASTMLAPRLFKEFEIETGKSTWLLGLAGITEGAIPMAIEDPLRVIGSFVL GSMVTGAIVGAMNIGLSTPGAGIFSLFLLHDNGAGGVMAAIGWFGAALVGAAISTAILLMWRRHAVKHGNYLTDGVMP >Mature_638_residues MNLTTLTHRDALCLNARFTSREEAIHVLTQRLAALGKISSTEQFLEEVYRRESLGPTALGEGLAVPHGKTAAVKEAAFAV ATLSEPLQWEGVDGPEAVDLVVLLAIPPNEAGTTHMQLLTALTTRLADDEIRARIQSATTPDELLSALDDKGGTQPSASF SNAPTIVCVTACPAGIAHTYMAAEYLEKAGRKLGVNVYVEKQGANGIEGRLTADQLNSATACIFAAEVAIKESERFNGIP ALSVPVAEPIRHAEALIQQALTLKRSDETRTVQQDTQPVKSVKTELKQALLSGISFAVPLIVAGGTVLAVAVLLSQIFGL QDLFNEENSWLWMYRKLGGGLLGILMVPVLAAYTAYSLADKPALAPGFAAGLAANMIGSGFLGAVVGGLIAGYLMRWVKN HLRLSSKFNGFLTFYLYPVLGTLGAGSLMLFVVGEPVAWINNSLTAWLNGLSGSNALLLGAILGFMCSFDLGGPVNKAAY AFCLGAMANGVYGPYAIFASVKMVSAFTVTASTMLAPRLFKEFEIETGKSTWLLGLAGITEGAIPMAIEDPLRVIGSFVL GSMVTGAIVGAMNIGLSTPGAGIFSLFLLHDNGAGGVMAAIGWFGAALVGAAISTAILLMWRRHAVKHGNYLTDGVMP
Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane [H]
COG id: COG1299
COG function: function code G; Phosphotransferase system, fructose-specific IIC component
Gene ontology:
Cell location: Cell inner membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PTS EIIC type-2 domain [H]
Homologues:
Organism=Escherichia coli, GI1786951, Length=638, Percent_Identity=99.8432601880878, Blast_Score=1283, Evalue=0.0, Organism=Escherichia coli, GI1788492, Length=473, Percent_Identity=35.5179704016913, Blast_Score=268, Evalue=1e-72, Organism=Escherichia coli, GI87082348, Length=480, Percent_Identity=32.9166666666667, Blast_Score=222, Evalue=7e-59, Organism=Escherichia coli, GI1790386, Length=289, Percent_Identity=39.1003460207612, Blast_Score=189, Evalue=4e-49, Organism=Escherichia coli, GI1788729, Length=392, Percent_Identity=27.2959183673469, Blast_Score=110, Evalue=3e-25, Organism=Escherichia coli, GI1790387, Length=94, Percent_Identity=43.6170212765958, Blast_Score=85, Evalue=1e-17, Organism=Escherichia coli, GI1788730, Length=103, Percent_Identity=34.9514563106796, Blast_Score=74, Evalue=2e-14, Organism=Escherichia coli, GI1789597, Length=159, Percent_Identity=28.3018867924528, Blast_Score=71, Evalue=2e-13, Organism=Escherichia coli, GI1788726, Length=136, Percent_Identity=27.2058823529412, Blast_Score=70, Evalue=4e-13, Organism=Escherichia coli, GI48994992, Length=139, Percent_Identity=25.1798561151079, Blast_Score=69, Evalue=1e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR016152 - InterPro: IPR002178 - InterPro: IPR013011 - InterPro: IPR003501 - InterPro: IPR003352 - InterPro: IPR013014 - InterPro: IPR004715 - InterPro: IPR003353 - InterPro: IPR006327 [H]
Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]
EC number: =2.7.1.69 [H]
Molecular weight: Translated: 67073; Mature: 67073
Theoretical pI: Translated: 6.20; Mature: 6.20
Prosite motif: PS00372 PTS_EIIA_TYPE_2_HIS ; PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2 ; PS51104 PTS_EIIC_TYPE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNLTTLTHRDALCLNARFTSREEAIHVLTQRLAALGKISSTEQFLEEVYRRESLGPTALG CCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHCC EGLAVPHGKTAAVKEAAFAVATLSEPLQWEGVDGPEAVDLVVLLAIPPNEAGTTHMQLLT CCCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEEEEECCCCCCHHHHHHHH ALTTRLADDEIRARIQSATTPDELLSALDDKGGTQPSASFSNAPTIVCVTACPAGIAHTY HHHHHHCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHH MAAEYLEKAGRKLGVNVYVEKQGANGIEGRLTADQLNSATACIFAAEVAIKESERFNGIP HHHHHHHHCCCEECCEEEEEECCCCCCCCCEEHHHHCCHHHHHHHHHHHHHHHHHCCCCC ALSVPVAEPIRHAEALIQQALTLKRSDETRTVQQDTQPVKSVKTELKQALLSGISFAVPL CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH IVAGGTVLAVAVLLSQIFGLQDLFNEENSWLWMYRKLGGGLLGILMVPVLAAYTAYSLAD HHCCHHHHHHHHHHHHHHCHHHHHCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHCC KPALAPGFAAGLAANMIGSGFLGAVVGGLIAGYLMRWVKNHLRLSSKFNGFLTFYLYPVL CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH GTLGAGSLMLFVVGEPVAWINNSLTAWLNGLSGSNALLLGAILGFMCSFDLGGPVNKAAY HHCCCCCEEEEEECCCHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHH AFCLGAMANGVYGPYAIFASVKMVSAFTVTASTMLAPRLFKEFEIETGKSTWLLGLAGIT HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC EGAIPMAIEDPLRVIGSFVLGSMVTGAIVGAMNIGLSTPGAGIFSLFLLHDNGAGGVMAA CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEEECCCCCHHHHH IGWFGAALVGAAISTAILLMWRRHAVKHGNYLTDGVMP HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC >Mature Secondary Structure MNLTTLTHRDALCLNARFTSREEAIHVLTQRLAALGKISSTEQFLEEVYRRESLGPTALG CCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHCC EGLAVPHGKTAAVKEAAFAVATLSEPLQWEGVDGPEAVDLVVLLAIPPNEAGTTHMQLLT CCCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCEEEEEEEEECCCCCCHHHHHHHH ALTTRLADDEIRARIQSATTPDELLSALDDKGGTQPSASFSNAPTIVCVTACPAGIAHTY HHHHHHCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHH MAAEYLEKAGRKLGVNVYVEKQGANGIEGRLTADQLNSATACIFAAEVAIKESERFNGIP HHHHHHHHCCCEECCEEEEEECCCCCCCCCEEHHHHCCHHHHHHHHHHHHHHHHHCCCCC ALSVPVAEPIRHAEALIQQALTLKRSDETRTVQQDTQPVKSVKTELKQALLSGISFAVPL CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH IVAGGTVLAVAVLLSQIFGLQDLFNEENSWLWMYRKLGGGLLGILMVPVLAAYTAYSLAD HHCCHHHHHHHHHHHHHHCHHHHHCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHCC KPALAPGFAAGLAANMIGSGFLGAVVGGLIAGYLMRWVKNHLRLSSKFNGFLTFYLYPVL CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH GTLGAGSLMLFVVGEPVAWINNSLTAWLNGLSGSNALLLGAILGFMCSFDLGGPVNKAAY HHCCCCCEEEEEECCCHHHHCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHH AFCLGAMANGVYGPYAIFASVKMVSAFTVTASTMLAPRLFKEFEIETGKSTWLLGLAGIT HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC EGAIPMAIEDPLRVIGSFVLGSMVTGAIVGAMNIGLSTPGAGIFSLFLLHDNGAGGVMAA CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEEEEEECCCCCHHHHH IGWFGAALVGAAISTAILLMWRRHAVKHGNYLTDGVMP HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9063979; 9278503; 8905232 [H]