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The map label for this gene is fepG

Identifier: 157160085

GI number: 157160085

Start: 656277

End: 657269

Strand: Reverse

Name: fepG

Synonym: EcHS_A0640

Alternate gene names: 157160085

Gene position: 657269-656277 (Counterclockwise)

Preceding gene: 157160086

Following gene: 157160084

Centisome position: 14.15

GC content: 58.21

Gene sequence:

>993_bases
ATGATTTACGTCTCTCGCCGATTACTCATCACCTGTTTGCTGCTGGTTTCCGCCTGTGTGGTTGCAGGTATCTGGGGATT
ACGCAGCGGTGCCGTCACGCTGGAAACCTCGCAGGTATTCGCCGCGCTGATGGGCGATGCGCCGCGCAGTATGACGATGG
TGGTCACCGAATGGCGTTTACCACGCGTGCTGATGGCGCTGTTGATTGGCGCAGCACTGGGCGTCAGTGGCGCGATTTTT
CAGTCGCTGATGCGTAACCCGCTCGGCAGCCCTGACGTAATGGGCTTTAACACCGGGGCGTGGAGCGGCGTGCTGGTGGC
GATGGTGCTGTTTGGTCAGGACCTGACGGCTATCGCGCTGTCAGCAATGGTGGGCGGCATTGTCACTTCGCTGCTGGTCT
GGCTGCTCGCCTGGCGCAACGGCATCGACACCTTTCGGTTGATTATTATCGGTATCGGCGTTCGCGCCATGCTGGTGGCC
TTTAATACCTGGCTGTTGCTGAAAGCGTCTTTAGAAACGGCGCTAACAGCAGGTTTGTGGAATGCCGGATCGCTCAACGG
CCTGACGTGGGCAAAAACCTCGCCTTCCGCACCCATCATTATATTGATGCTCATTGCCGCCGCCTTACTGGTACGCCGGA
TGCGCTTGCTGGAAATGGGCGATGATACCGCGTGTGCGCTGGGCGTCAGCGTCGAACGTTCGCGTCTGTTAATGATGCTG
GTTGCAGTGGTGCTTACCGCTGCGGCAACAGCGCTTGCCGGGCCGATTTCCTTTATTGCTTTAGTCGCACCGCACATTGC
CCGACGCATTAGCGGCACCGCTCGCTGGGGGCTAACCCAGGCGGCGCTATGCGGGGCGCTGTTACTGCTGGCGGCCGATC
TCTGCGCCCAACAACTGTTTATGCCGTATCAACTTCCGGTTGGCGTCGTTACCGTCAGCCTCGGCGGTATTTACCTTATC
GTCTTGTTAATTCAGGAGTCTCGCAAAAAATGA

Upstream 100 bases:

>100_bases
GGGTGATTGTGCCCGGCGAACTGCGCGTTTCTGTGGTCAGTGCGTTTATTGGTGCACCGGTGCTGATCTTCCTCGTGCGA
CGTAAAACGCGAGGTGGTGC

Downstream 100 bases:

>100_bases
CCGAATCAGTAGCCCGTTTGCGCGGCGAACAGTTAACCCTGGGATATGGCAAATATACCGTTGCGGAAAATCTGACTGTA
GAAATACCTGATGGTCACTT

Product: iron-enterobactin transporter permease

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MIYVSRRLLITCLLLVSACVVAGIWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIF
QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALSAMVGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA
FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMML
VAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLI
VLLIQESRKK

Sequences:

>Translated_330_residues
MIYVSRRLLITCLLLVSACVVAGIWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIF
QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALSAMVGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA
FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMML
VAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLI
VLLIQESRKK
>Mature_330_residues
MIYVSRRLLITCLLLVSACVVAGIWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIF
QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALSAMVGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA
FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMML
VAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLI
VLLIQESRKK

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane

COG id: COG4779

COG function: function code P; ABC-type enterobactin transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily

Homologues:

Organism=Escherichia coli, GI1786804, Length=330, Percent_Identity=100, Blast_Score=635, Evalue=0.0,
Organism=Escherichia coli, GI1790740, Length=288, Percent_Identity=37.8472222222222, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1786347, Length=277, Percent_Identity=35.3790613718412, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1786805, Length=309, Percent_Identity=36.5695792880259, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790741, Length=280, Percent_Identity=34.2857142857143, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1788004, Length=294, Percent_Identity=34.6938775510204, Blast_Score=98, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FEPG_ECOLI (P23877)

Other databases:

- EMBL:   X57471
- EMBL:   U82598
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   C64792
- RefSeq:   AP_001236.1
- RefSeq:   NP_415121.1
- ProteinModelPortal:   P23877
- SMR:   P23877
- DIP:   DIP-9597N
- STRING:   P23877
- EnsemblBacteria:   EBESCT00000001407
- EnsemblBacteria:   EBESCT00000001408
- EnsemblBacteria:   EBESCT00000015813
- GeneID:   945209
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW0581
- KEGG:   eco:b0589
- EchoBASE:   EB0294
- EcoGene:   EG10298
- eggNOG:   COG4779
- GeneTree:   EBGT00050000008910
- HOGENOM:   HBG700016
- OMA:   AYVANLP
- ProtClustDB:   PRK10440
- BioCyc:   EcoCyc:FEPG-MONOMER
- Genevestigator:   P23877
- InterPro:   IPR000522

Pfam domain/function: PF01032 FecCD

EC number: NA

Molecular weight: Translated: 34911; Mature: 34911

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12b42c58)-; HASH(0x403a8e4c)-; HASH(0x403a8f78)-; HASH(0x403a9908)-; HASH(0x12fadcf4)-; HASH(0x403a99ec)-; HASH(0x403a9638)-; HASH(0x403a8f18)-; HASH(0x403a96c8)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYVSRRLLITCLLLVSACVVAGIWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRL
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCEEEEEHHHH
PRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIAL
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHH
SAMVGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVAFNTWLLLKASLETALTAGLW
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMML
CCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHH
VAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHC
MPYQLPVGVVTVSLGGIYLIVLLIQESRKK
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MIYVSRRLLITCLLLVSACVVAGIWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRL
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCEEEEEHHHH
PRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIAL
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHH
SAMVGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVAFNTWLLLKASLETALTAGLW
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMML
CCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHH
VAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHC
MPYQLPVGVVTVSLGGIYLIVLLIQESRKK
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1838574; 9278503