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The map label for this gene is hokE [H]

Identifier: 157160074

GI number: 157160074

Start: 643818

End: 644069

Strand: Direct

Name: hokE [H]

Synonym: EcHS_A0629

Alternate gene names: 157160074

Gene position: 643818-644069 (Clockwise)

Preceding gene: 157160068

Following gene: 157160075

Centisome position: 13.86

GC content: 47.62

Gene sequence:

>252_bases
ATGAAGCCCCAGGAGATATTTCTATCAACCCTGGGGCTGCCACTCCAAACCCGAACAATTTGGATGGTAGTCCCTTCTTC
GCATGGAGGCAATATAAACATGCTGACGAAATATGCCCTTGCGGCAGTCATAGTGCTGTGTTTAACGGTGCTGGGATTTA
CGCTTCTGGTCGGAGATTCGCTGTGTGAGTTCACCGTAAAGGAACGTAATATTGAGTTTAAGGCTGTTCTCGCTTACGAA
CCGAAGAAGTAG

Upstream 100 bases:

>100_bases
ACTCACTGTATAAATAAACAGCTATTTTGTTGAGGAAGGGTAAGATAACGGCGGGTGCCTGAAGCTTTCCGGTTTCAGGT
TTACTCTGAGGTCTGGAAAG

Downstream 100 bases:

>100_bases
CCGTTGTGCGGGGAGCAATCCCATAAGCGCTAACTTAAGGGTTGTGGTATTACGCCTGATATGATTTAACGTGCCGATGA
ATTACTCTCACGATAACTGG

Product: Hok/Gef family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 83; Mature: 83

Protein sequence:

>83_residues
MKPQEIFLSTLGLPLQTRTIWMVVPSSHGGNINMLTKYALAAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVLAYE
PKK

Sequences:

>Translated_83_residues
MKPQEIFLSTLGLPLQTRTIWMVVPSSHGGNINMLTKYALAAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVLAYE
PKK
>Mature_83_residues
MKPQEIFLSTLGLPLQTRTIWMVVPSSHGGNINMLTKYALAAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVLAYE
PKK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hok/gef family [H]

Homologues:

Organism=Escherichia coli, GI48994879, Length=50, Percent_Identity=100, Blast_Score=101, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000021
- InterPro:   IPR018084
- ProDom:   PD005979 [H]

Pfam domain/function: PF01848 HOK_GEF [H]

EC number: NA

Molecular weight: Translated: 9212; Mature: 9212

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS00556 HOK_GEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPQEIFLSTLGLPLQTRTIWMVVPSSHGGNINMLTKYALAAVIVLCLTVLGFTLLVGDS
CCHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LCEFTVKERNIEFKAVLAYEPKK
HHEEEECCCCCEEEEEEEECCCC
>Mature Secondary Structure
MKPQEIFLSTLGLPLQTRTIWMVVPSSHGGNINMLTKYALAAVIVLCLTVLGFTLLVGDS
CCHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LCEFTVKERNIEFKAVLAYEPKK
HHEEEECCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]