| Definition | Escherichia coli HS, complete genome. |
|---|---|
| Accession | NC_009800 |
| Length | 4,643,538 |
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The map label for this gene is ybbO
Identifier: 157160022
GI number: 157160022
Start: 584506
End: 585315
Strand: Reverse
Name: ybbO
Synonym: EcHS_A0572
Alternate gene names: 157160022
Gene position: 585315-584506 (Counterclockwise)
Preceding gene: 157160023
Following gene: 157160021
Centisome position: 12.6
GC content: 54.2
Gene sequence:
>810_bases ATGACTCATAAAGCAACGGAGATCCTGACAGGTAAAGTTATGCAAAAATCGGTCTTAATTACCGGATGTTCCAGTGGAAT TGGCCTGGAAAGCGCGCTCGAATTAAAACGCCAGGGTTTTCATGTGCTGGCAGGTTGCCGGAAACCGGATGATGTTGAGC GTATGAACAGCATGGGATTTACCGGCGTGTTGATCGATCTGGATTCGCCAGAAAGTGTTGATCGCGCAGCCGACGAAGTG ATCGCCCTGACCGATAATTGTCTGTATGGGATCTTTAACAATGCCGGATTCGGCATGTATGGCCCCCTTTCCACCATCAG CCGTGCGCAGATGGAACAGCAGTTTTCCGCCAACTTTTTCGGCGCACACCAGCTCACCATGCGCCTGTTACCCGCGATGT TACCGCACGGTGAAGGGCGTATTGTGATGACATCATCGGTGATGGGATTAATCTCCACGCCGGGTCGTGGCGCTTACGCG GCCAGTAAATATGCGCTGGAGGCGTGGTCAGACGCACTGCGCATGGAGCTGCGCCACAGCGGAATTAAAGTCAGCCTGAT CGAACCCGGTCCCATTCGTACTCGCTTCACCGACAACGTCAACCAGACGCAAAGTGATAAACCAGTCGAAAATCCCGGCA TCGCCGCCCGCTTTACGTTGGGACCGGAAGCGGTGGTGGACAAAGTACGCCATGCTTTTATTAGCGAGAAGCCGAAGATG CGCTATCCGGTAACGCTGGTGACCTGGGCAGTAATGGTGCTCAAGCGCCTGCTGCCGGGGCGCGTGATGGACAAAATATT GCAGGGGTGA
Upstream 100 bases:
>100_bases AAGCCACAATGGATGCAGGATGACGGTATTCATCCCAACCGCGACGCCCAGCCGTTTATTGCCGACTGGATGGCGAAGCA GTTGCAGCCTTTAGTAAATC
Downstream 100 bases:
>100_bases GTTGAAGCGCGCGCTTAAGCCCCCATGTCAAAGAAAATATCGACAACAGAGAGCGACTCCATGTCCGTAGAAAATATTGT CAACATTAACGAATCTAACC
Product: short chain dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 269; Mature: 268
Protein sequence:
>269_residues MTHKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNSMGFTGVLIDLDSPESVDRAADEV IALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYA ASKYALEAWSDALRMELRHSGIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVDKVRHAFISEKPKM RYPVTLVTWAVMVLKRLLPGRVMDKILQG
Sequences:
>Translated_269_residues MTHKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNSMGFTGVLIDLDSPESVDRAADEV IALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYA ASKYALEAWSDALRMELRHSGIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVDKVRHAFISEKPKM RYPVTLVTWAVMVLKRLLPGRVMDKILQG >Mature_268_residues THKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNSMGFTGVLIDLDSPESVDRAADEVI ALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYAA SKYALEAWSDALRMELRHSGIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVDKVRHAFISEKPKMR YPVTLVTWAVMVLKRLLPGRVMDKILQG
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family
Homologues:
Organism=Homo sapiens, GI7657478, Length=188, Percent_Identity=39.3617021276596, Blast_Score=123, Evalue=2e-28, Organism=Homo sapiens, GI50726952, Length=186, Percent_Identity=39.247311827957, Blast_Score=116, Evalue=2e-26, Organism=Homo sapiens, GI40548397, Length=262, Percent_Identity=30.5343511450382, Blast_Score=114, Evalue=8e-26, Organism=Homo sapiens, GI214010158, Length=262, Percent_Identity=30.5343511450382, Blast_Score=114, Evalue=8e-26, Organism=Homo sapiens, GI214010156, Length=262, Percent_Identity=30.5343511450382, Blast_Score=114, Evalue=8e-26, Organism=Homo sapiens, GI22758144, Length=262, Percent_Identity=30.5343511450382, Blast_Score=114, Evalue=8e-26, Organism=Homo sapiens, GI150247226, Length=254, Percent_Identity=33.0708661417323, Blast_Score=112, Evalue=3e-25, Organism=Homo sapiens, GI22507405, Length=286, Percent_Identity=30.4195804195804, Blast_Score=112, Evalue=4e-25, Organism=Homo sapiens, GI44680136, Length=289, Percent_Identity=29.0657439446367, Blast_Score=109, Evalue=3e-24, Organism=Homo sapiens, GI44680133, Length=289, Percent_Identity=29.0657439446367, Blast_Score=109, Evalue=3e-24, Organism=Homo sapiens, GI17738292, Length=289, Percent_Identity=29.0657439446367, Blast_Score=109, Evalue=3e-24, Organism=Homo sapiens, GI19743808, Length=281, Percent_Identity=30.9608540925267, Blast_Score=105, Evalue=5e-23, Organism=Homo sapiens, GI119392083, Length=213, Percent_Identity=36.6197183098592, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI223718074, Length=195, Percent_Identity=33.8461538461538, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI7706318, Length=269, Percent_Identity=26.3940520446097, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI20149619, Length=198, Percent_Identity=31.8181818181818, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI157739938, Length=193, Percent_Identity=31.6062176165803, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI4504503, Length=206, Percent_Identity=31.5533980582524, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI142976729, Length=260, Percent_Identity=27.3076923076923, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI40807363, Length=254, Percent_Identity=30.7086614173228, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI210032110, Length=191, Percent_Identity=29.8429319371728, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI32483357, Length=189, Percent_Identity=25.3968253968254, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI32455239, Length=190, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI5031765, Length=190, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI4503817, Length=227, Percent_Identity=26.8722466960352, Blast_Score=67, Evalue=1e-11, Organism=Escherichia coli, GI1786701, Length=269, Percent_Identity=100, Blast_Score=558, Evalue=1e-160, Organism=Escherichia coli, GI87082100, Length=206, Percent_Identity=31.0679611650485, Blast_Score=81, Evalue=8e-17, Organism=Escherichia coli, GI1789378, Length=213, Percent_Identity=28.169014084507, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1787335, Length=192, Percent_Identity=26.0416666666667, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI87082160, Length=190, Percent_Identity=25.2631578947368, Blast_Score=62, Evalue=5e-11, Organism=Escherichia coli, GI2367365, Length=189, Percent_Identity=30.6878306878307, Blast_Score=61, Evalue=7e-11, Organism=Caenorhabditis elegans, GI115534660, Length=287, Percent_Identity=29.9651567944251, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI32563809, Length=303, Percent_Identity=26.7326732673267, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17507613, Length=303, Percent_Identity=26.7326732673267, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI193210355, Length=264, Percent_Identity=30.6818181818182, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17557780, Length=297, Percent_Identity=28.2828282828283, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17570069, Length=194, Percent_Identity=32.4742268041237, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI71997402, Length=194, Percent_Identity=29.8969072164948, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17560676, Length=239, Percent_Identity=28.4518828451883, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI193203117, Length=275, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI193203115, Length=265, Percent_Identity=26.7924528301887, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17559962, Length=203, Percent_Identity=30.0492610837438, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6322067, Length=189, Percent_Identity=30.1587301587302, Blast_Score=75, Evalue=1e-14, Organism=Saccharomyces cerevisiae, GI6323882, Length=203, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=6e-13, Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=33.5051546391753, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI24651139, Length=237, Percent_Identity=31.6455696202532, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI21356301, Length=222, Percent_Identity=27.9279279279279, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24643142, Length=205, Percent_Identity=27.3170731707317, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI28571526, Length=186, Percent_Identity=31.1827956989247, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI45554248, Length=200, Percent_Identity=32.5, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24640117, Length=200, Percent_Identity=32.5, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24644339, Length=190, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI21357041, Length=188, Percent_Identity=28.7234042553192, Blast_Score=64, Evalue=8e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): YBBO_ECOL6 (P0AFP5)
Other databases:
- EMBL: AE014075 - RefSeq: NP_752547.1 - ProteinModelPortal: P0AFP5 - SMR: P0AFP5 - EnsemblBacteria: EBESCT00000044979 - GeneID: 1036368 - GenomeReviews: AE014075_GR - KEGG: ecc:c0614 - GeneTree: EBGT00050000009182 - HOGENOM: HBG750976 - OMA: WAVMVLE - ProtClustDB: PRK08017 - GO: GO:0005488 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 - Gene3D: G3DSA:3.40.50.720 - PANTHER: PTHR19410 - PRINTS: PR00081
Pfam domain/function: PF00106 adh_short
EC number: 1.-.-.- [C]
Molecular weight: Translated: 29411; Mature: 29279
Theoretical pI: Translated: 9.15; Mature: 9.15
Prosite motif: PS00061 ADH_SHORT
Important sites: ACT_SITE 159-159 BINDING 146-146
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 5.2 %Met (Translated Protein) 6.3 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 4.9 %Met (Mature Protein) 6.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTHKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNSMGF CCCCHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCC TGVLIDLDSPESVDRAADEVIALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFF EEEEEECCCCHHHHHHHHHEEEECCCCEEEHCCCCCCCCCCCHHHHHHHHHHHHHCCCCC GAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRHS CHHHHHHHHHHHHCCCCCCCEEEEECHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHC GIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVDKVRHAFISEKPKM CEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCC RYPVTLVTWAVMVLKRLLPGRVMDKILQG CCCHHHHHHHHHHHHHHCCHHHHHHHHCC >Mature Secondary Structure THKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNSMGF CCCHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCC TGVLIDLDSPESVDRAADEVIALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFF EEEEEECCCCHHHHHHHHHEEEECCCCEEEHCCCCCCCCCCCHHHHHHHHHHHHHCCCCC GAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRHS CHHHHHHHHHHHHCCCCCCCEEEEECHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHC GIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVDKVRHAFISEKPKM CEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCC RYPVTLVTWAVMVLKRLLPGRVMDKILQG CCCHHHHHHHHHHHHHHCCHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 12471157