Click here to switch to the map view.

The map label for this gene is acpH

Identifier: 157159924

GI number: 157159924

Start: 488129

End: 488710

Strand: Reverse

Name: acpH

Synonym: EcHS_A0474

Alternate gene names: 157159924

Gene position: 488710-488129 (Counterclockwise)

Preceding gene: 157159932

Following gene: 157159920

Centisome position: 10.52

GC content: 52.58

Gene sequence:

>582_bases
ATGAATTTTTTAGCTCACCTGCATTTAGCCCATCTCGCGGAAAGCTCGCTTTCCGGCAATTTACTGGCTGATTTCGTACG
CGGAAATCCTGAAGAAAGTTTTCCGCCCGACGTCGTGGCTGGCATTCATATGCATCGACGTATCGACGTATTAACCGACA
ATCTGCCGGAAGTCCGCGAAGCACGGGAATGGTTTCGTAGTGAAACTCGCCGCGTTGCGCCTATTACGCTGGATGTCATG
TGGGATCACTTTCTTTCCCGCCACTGGTCGCAGCTGTCGCCGGACTTTCCGCTACAGGAATTTGTCTGTTATGCCCGCGA
GCAAGTGATGACGATTTTGCCGGACTCACCGCCACGTTTTATCAATCTGAACAATTACTTGTGGTCAGAGCAGTGGCTGG
TGCGCTATCGCGATATGGATTTCATCCAGAACGTGTTAAACGGCATGGCAAGCCGCCGCCCACGTCTGGATGCCCTGCGT
GACTCCTGGTACGATTTAGACGCTCATTATGACGCCCTCGAAACCCGCTTCTGGCAGTTTTATCCGCGGATGATGGCGCA
GGCGTCACACAAGGCGTTATAA

Upstream 100 bases:

>100_bases
ACGCGCATGACACTGACTCAGACTAAAATAAGAGGCGGGTAGTCTAGTGCCGGGGCGCTCTCCCTGCAACCTTTACCCCC
TTTTGGATAGAATATAATCG

Downstream 100 bases:

>100_bases
AACGTTAGTTCATCCATACCGTAGCCGAAATGGCAGGCAAAGCCAGAATCCCGTCAGTCAGTTGCCCATGCCCTTCTTTG
CATTGCCATTGCACGGCATT

Product: acyl carrier protein phosphodiesterase

Products: NA

Alternate protein names: ACP phosphodiesterase

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHMHRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVM
WDHFLSRHWSQLSPDFPLQEFVCYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALR
DSWYDLDAHYDALETRFWQFYPRMMAQASHKAL

Sequences:

>Translated_193_residues
MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHMHRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVM
WDHFLSRHWSQLSPDFPLQEFVCYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALR
DSWYDLDAHYDALETRFWQFYPRMMAQASHKAL
>Mature_193_residues
MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHMHRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVM
WDHFLSRHWSQLSPDFPLQEFVCYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALR
DSWYDLDAHYDALETRFWQFYPRMMAQASHKAL

Specific function: Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP

COG id: COG3124

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AcpH family

Homologues:

Organism=Escherichia coli, GI1786605, Length=193, Percent_Identity=99.4818652849741, Blast_Score=394, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPH_ECO24 (A7ZIF6)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001461585.1
- STRING:   A7ZIF6
- EnsemblBacteria:   EBESCT00000022024
- GeneID:   5590041
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_0434
- eggNOG:   COG3124
- GeneTree:   EBGT00050000011754
- HOGENOM:   HBG420671
- OMA:   LAYYWEE
- ProtClustDB:   PRK10045
- BioCyc:   ECOL331111:ECE24377A_0434-MONOMER
- HAMAP:   MF_01950
- InterPro:   IPR007431
- PIRSF:   PIRSF011489

Pfam domain/function: PF04336 DUF479

EC number: =3.1.4.14

Molecular weight: Translated: 22942; Mature: 22942

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHMHRRIDVLTDNLPEVRE
CCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
AREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFVCYAREQVMTILPDSPPRF
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCE
INLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALRDSWYDLDAHYDALETRFWQF
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
YPRMMAQASHKAL
HHHHHHHHHHCCC
>Mature Secondary Structure
MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHMHRRIDVLTDNLPEVRE
CCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHH
AREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFVCYAREQVMTILPDSPPRF
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCE
INLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALRDSWYDLDAHYDALETRFWQF
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHH
YPRMMAQASHKAL
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA