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The map label for this gene is iraP

Identifier: 157159901

GI number: 157159901

Start: 465283

End: 465543

Strand: Direct

Name: iraP

Synonym: EcHS_A0450

Alternate gene names: 157159901

Gene position: 465283-465543 (Clockwise)

Preceding gene: 157159900

Following gene: 157159902

Centisome position: 10.02

GC content: 46.36

Gene sequence:

>261_bases
ATGAAAAATCTCATTGCTGAGTTGTTATTTAAGCTTGCCCAAAAAGAAGAAGAGTCGAAAGAACTGTGTGCGCAGGTAGA
AGCTTTGGAGATTATCGTCACTGCAATGCTTCGCAATATGGCGCAAAATGACCAACAGCGGTTGATTGATCAGGTAGAGG
GGGCGCTGTACGAGGTAAAGCCCGATGCCAGCATTCCTGACGACGATACGGAGCTGCTGCGCGATTACGTAAAGAAGTTA
TTGAAGCATCCTCGTCAGTAA

Upstream 100 bases:

>100_bases
GCAAAGTATTTCCTTTGTCATAAAAATAATACTTCCAGACACTATGAAGTTGTGAAACATAATGTTAACTTCTCCATACT
TTGGATAAGGAAATACAGAC

Downstream 100 bases:

>100_bases
AAAGTTAATCTTTTCAACAGCTGTCATAAAGTTGTCACGGCCGAGACTTATAGTCGCTTTGTTTTTATTTTTTAATGTAT
TTGTACATGGAGAAAATAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 86; Mature: 86

Protein sequence:

>86_residues
MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQNDQQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKL
LKHPRQ

Sequences:

>Translated_86_residues
MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQNDQQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKL
LKHPRQ
>Mature_86_residues
MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQNDQQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKL
LKHPRQ

Specific function: Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is du

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iraP family

Homologues:

Organism=Escherichia coli, GI1786581, Length=86, Percent_Identity=100, Blast_Score=172, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IRAP_ECO24 (A7ZID1)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001461560.1
- ProteinModelPortal:   A7ZID1
- STRING:   A7ZID1
- EnsemblBacteria:   EBESCT00000020145
- GeneID:   5587333
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_0409
- eggNOG:   NOG13415
- GeneTree:   EBGT00050000010221
- HOGENOM:   HBG416557
- OMA:   HMEHDAQ
- ProtClustDB:   PRK10244
- BioCyc:   ECOL331111:ECE24377A_0409-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01198
- InterPro:   IPR019732

Pfam domain/function: PF10796 Anti-adapt_IraP

EC number: NA

Molecular weight: Translated: 9938; Mature: 9938

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQNDQQRLIDQVEGALYEVK
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCC
PDASIPDDDTELLRDYVKKLLKHPRQ
CCCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQNDQQRLIDQVEGALYEVK
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCC
PDASIPDDDTELLRDYVKKLLKHPRQ
CCCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA