Click here to switch to the map view.

The map label for this gene is rbsC [H]

Identifier: 157159842

GI number: 157159842

Start: 407830

End: 408786

Strand: Direct

Name: rbsC [H]

Synonym: EcHS_A0389

Alternate gene names: 157159842

Gene position: 407830-408786 (Clockwise)

Preceding gene: 157159841

Following gene: 157159843

Centisome position: 8.78

GC content: 51.31

Gene sequence:

>957_bases
ATGAAAAAATCGTGGCGTAATAACGTTGAGTTTTACTTGATCGGCCTGCTGGTGCTAACTGTTGCCGCGTTCAGCATTAC
TATGCCGGAGATTTTCTGGTCGATAAGTAATTTCCAGTCCGTCGCTTCGCAAATGCCCGTGCTGGGCATTCTGGCGTTGG
CTATGGCGGTGACCATGCTTTGCGGTGGCATTAACTTGTCAATTATAGCCACTGCTAACGCCTGTTCACTGGTGATGGCG
TGGGTGGCGACTCAGTATCCACCGGGTATTGCTACGGTTGTCGCTACGTTACTGGCGGGCGCTGGCGCGGCGGTGATAAT
CGGTTTATGTAACGGCGTATTGATTGCTGGTATTCGAGTGTCGCCAATTCTTGCAACGCTTGGGATGATGACGTTGCTCA
AAGGGATAAATATTCTGGTGACAGGTGGTAGCGCCATTGCCAATTATCCCTCATGGGTGCTGTGGTTGAATCATGCGCAA
TGGTTCGGTATTCCGCTACCGATGTGGTTGTTTGCCGCAGTGGCACTGGGGCTATGGATATTGCTGGAGAAAACGCCGCT
CGGTAAAGCCATTTACCTGATTGGGTCTAACGAACGAGCAACACTTTACTCCGGCATTAACACTCGTCGGGTGCTGATTT
GGGTTTATGTCATTTCCGCCTTGCTTTGTGCGGTAGCGGCATTTTTGATGATGTCGAAACTCAACTCGGCTAAGGCCTCT
TATGGCGAATCGTACTTGCTGGTGTCAATCCTCGCGGCAGTACTCGGTGGGGTTAATCCGGACGGCGGCAGCGGGCGGAT
AATTGGTATGGTGCTGGCGCTGTTTCTTCTGCAAATTATTGAAAGCGGCTTCAATATTCTCGGTATAAGCCCCTACCTGA
CGATGGCCTTATGGGGAACGTTGCTGCTCTGTTTCATTCAGGTTCGCGGCATGTTGGGGCTGGATCGGGTGGTTTAA

Upstream 100 bases:

>100_bases
TGGGAGTCTCGTCTTACTGGCAAACATTGATCACCGGCATCATCATCGTTGCCAGCATTAGTGCCACGGCGTGGAGTCAG
CATCAGAACCGGAGTCTGCT

Downstream 100 bases:

>100_bases
ATATTGGCTATATTCAATGGACGCGTTTTGCCGCGATGACATATCAGGCGTCGCCAAATACACATAGCTAATCAGGAGTA
AACACAATGAAGATCAAAGC

Product: sugar ABC transporter, permease protein

Products: ADP; phosphate; ribose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MKKSWRNNVEFYLIGLLVLTVAAFSITMPEIFWSISNFQSVASQMPVLGILALAMAVTMLCGGINLSIIATANACSLVMA
WVATQYPPGIATVVATLLAGAGAAVIIGLCNGVLIAGIRVSPILATLGMMTLLKGINILVTGGSAIANYPSWVLWLNHAQ
WFGIPLPMWLFAAVALGLWILLEKTPLGKAIYLIGSNERATLYSGINTRRVLIWVYVISALLCAVAAFLMMSKLNSAKAS
YGESYLLVSILAAVLGGVNPDGGSGRIIGMVLALFLLQIIESGFNILGISPYLTMALWGTLLLCFIQVRGMLGLDRVV

Sequences:

>Translated_318_residues
MKKSWRNNVEFYLIGLLVLTVAAFSITMPEIFWSISNFQSVASQMPVLGILALAMAVTMLCGGINLSIIATANACSLVMA
WVATQYPPGIATVVATLLAGAGAAVIIGLCNGVLIAGIRVSPILATLGMMTLLKGINILVTGGSAIANYPSWVLWLNHAQ
WFGIPLPMWLFAAVALGLWILLEKTPLGKAIYLIGSNERATLYSGINTRRVLIWVYVISALLCAVAAFLMMSKLNSAKAS
YGESYLLVSILAAVLGGVNPDGGSGRIIGMVLALFLLQIIESGFNILGISPYLTMALWGTLLLCFIQVRGMLGLDRVV
>Mature_318_residues
MKKSWRNNVEFYLIGLLVLTVAAFSITMPEIFWSISNFQSVASQMPVLGILALAMAVTMLCGGINLSIIATANACSLVMA
WVATQYPPGIATVVATLLAGAGAAVIIGLCNGVLIAGIRVSPILATLGMMTLLKGINILVTGGSAIANYPSWVLWLNHAQ
WFGIPLPMWLFAAVALGLWILLEKTPLGKAIYLIGSNERATLYSGINTRRVLIWVYVISALLCAVAAFLMMSKLNSAKAS
YGESYLLVSILAAVLGGVNPDGGSGRIIGMVLALFLLQIIESGFNILGISPYLTMALWGTLLLCFIQVRGMLGLDRVV

Specific function: Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790191, Length=309, Percent_Identity=33.3333333333333, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1787794, Length=312, Percent_Identity=31.0897435897436, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI145693152, Length=250, Percent_Identity=30, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1790524, Length=314, Percent_Identity=26.1146496815287, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1788896, Length=295, Percent_Identity=29.1525423728814, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI145693214, Length=249, Percent_Identity=28.9156626506024, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789992, Length=120, Percent_Identity=31.6666666666667, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI87082395, Length=273, Percent_Identity=27.4725274725275, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1788471, Length=320, Percent_Identity=29.6875, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787793, Length=286, Percent_Identity=29.7202797202797, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 33796; Mature: 33796

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSWRNNVEFYLIGLLVLTVAAFSITMPEIFWSISNFQSVASQMPVLGILALAMAVTML
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
CGGINLSIIATANACSLVMAWVATQYPPGIATVVATLLAGAGAAVIIGLCNGVLIAGIRV
HCCCCEEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHEECCHH
SPILATLGMMTLLKGINILVTGGSAIANYPSWVLWLNHAQWFGIPLPMWLFAAVALGLWI
HHHHHHHHHHHHHCCCEEEEECCHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHH
LLEKTPLGKAIYLIGSNERATLYSGINTRRVLIWVYVISALLCAVAAFLMMSKLNSAKAS
HHCCCCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGESYLLVSILAAVLGGVNPDGGSGRIIGMVLALFLLQIIESGFNILGISPYLTMALWGT
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHH
LLLCFIQVRGMLGLDRVV
HHHHHHHHHHCCCHHHCC
>Mature Secondary Structure
MKKSWRNNVEFYLIGLLVLTVAAFSITMPEIFWSISNFQSVASQMPVLGILALAMAVTML
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
CGGINLSIIATANACSLVMAWVATQYPPGIATVVATLLAGAGAAVIIGLCNGVLIAGIRV
HCCCCEEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHEECCHH
SPILATLGMMTLLKGINILVTGGSAIANYPSWVLWLNHAQWFGIPLPMWLFAAVALGLWI
HHHHHHHHHHHHHCCCEEEEECCHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHH
LLEKTPLGKAIYLIGSNERATLYSGINTRRVLIWVYVISALLCAVAAFLMMSKLNSAKAS
HHCCCCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YGESYLLVSILAAVLGGVNPDGGSGRIIGMVLALFLLQIIESGFNILGISPYLTMALWGT
CCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHH
LLLCFIQVRGMLGLDRVV
HHHHHHHHHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ribose [Periplasm]; H2O [C]

Specific reaction: ATP + ribose [Periplasm] + H2O = ADP + phosphate + ribose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]