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The map label for this gene is cdaR [H]

Identifier: 157159629

GI number: 157159629

Start: 181334

End: 182491

Strand: Direct

Name: cdaR [H]

Synonym: EcHS_A0166

Alternate gene names: 157159629

Gene position: 181334-182491 (Clockwise)

Preceding gene: 157159628

Following gene: 157159634

Centisome position: 3.91

GC content: 52.76

Gene sequence:

>1158_bases
ATGGCTGGCTGGCATCTTGATACCAAAATGGCGCAGGATATCGTGGCACGTACCATGCGCATCATCGATACCAATATCAA
CGTAATGGATGCCCGTGGGCGAATTATCGGCAGCGGCGATCGTGAGCGTATTGGTGAATTGCACGAAGGTGCATTGCTGG
TACTTTCACAGGGACGAGTCGTCGATATCGATGACGCGGTGGCACGTCATCTGCACGGTGTGCGGCAAGGGATTAATCTA
CCGTTACGGCTGGAAGGTGAAATTGTCGGCGTAATTGGCCTGACAGGTGAACCAGAGAATCTGCGTAAATATGGCGAACT
GGTCTGCATGACGGCTGAAATGATGCTGGAACAGTCGCGGTTGATGCACTTGTTGGCTCAGGATAGCCGTTTGCGGGAGG
AACTGGTGATGAACCTGATTCAGGCAGAGGAGAATACTCCCGCACTTACTGAATGGGCGCAACGGCTGGGGATCGATCTC
AATCAACCGCGAGTGGTGGCTATTGTTGAGGTCGACAGCGGTCAGCTTGGTGTGGACAGCGCAATGGCGGAGTTACAACA
ACTGCAAAACGCGCTGACTACGCCCGAGCGTAATAATCTGGTGGCGATTGTCTCGCTAACCGAAATGGTGGTGTTGAAAC
CGGCGTTGAACTCTTTTGGGCGCTGGGATGCAGAAGATCATCGTAAGCGAGTTGAACAACTGATTACCCGCATGAAAGAG
TACGGCCAGCTGCGTTTTCGCGTTTCACTGGGCAACTATTTTACCGGTCCTGGCAGTATTGCCCGATCCTATCGTACGGC
GAAAACGACGATGGTGGTGGGTAAACAGCGGATGCCAGAAAGTCGCTGCTATTTTTATCAGGATCTGATGTTACCTGTGT
TACTCGACAGTTTGCGTGGCGACTGGCAGGCCAACGAACTGGCGCGACCGCTGGCGCGGCTGAAAGCGATGGACAATAAC
GGCTTGCTGCGACGAACGCTGGCGGCGTGGTTTCGTCACAATGTGCAACCGCTGGCAACGTCAAAGGCGTTGTTTATTCA
TCGTAATACTCTGGAGTATCGGCTTAATCGTATATCGGAACTGACCGGGCTTGATTTGGGTAATTTTGATGACAGGTTGC
TGCTGTATGTGGCGTTGCAGCTGGATGAAGAGCGGTAG

Upstream 100 bases:

>100_bases
CTTCACCACAACTCCATACATCTTCATCATCCTTTAGGCATTTGCACAATGCCGTACGTTACGTACTTCCTTATGCTAAG
CCGTGCATAACGGAGGACTT

Downstream 100 bases:

>100_bases
GTTATGCGTTAAGGTCGAGGCGGCGCTGGCTCATTCCCCTCAGCCCGAAGGGTAGAGGGGAATGTCCGAGTTAACCGTCA
GTTCGGCATTATTTACGCGT

Product: carbohydrate diacid transcriptional activator CdaR

Products: NA

Alternate protein names: Sugar diacid regulator [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERIGELHEGALLVLSQGRVVDIDDAVARHLHGVRQGINL
PLRLEGEIVGVIGLTGEPENLRKYGELVCMTAEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDL
NQPRVVAIVEVDSGQLGVDSAMAELQQLQNALTTPERNNLVAIVSLTEMVVLKPALNSFGRWDAEDHRKRVEQLITRMKE
YGQLRFRVSLGNYFTGPGSIARSYRTAKTTMVVGKQRMPESRCYFYQDLMLPVLLDSLRGDWQANELARPLARLKAMDNN
GLLRRTLAAWFRHNVQPLATSKALFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEER

Sequences:

>Translated_385_residues
MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERIGELHEGALLVLSQGRVVDIDDAVARHLHGVRQGINL
PLRLEGEIVGVIGLTGEPENLRKYGELVCMTAEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDL
NQPRVVAIVEVDSGQLGVDSAMAELQQLQNALTTPERNNLVAIVSLTEMVVLKPALNSFGRWDAEDHRKRVEQLITRMKE
YGQLRFRVSLGNYFTGPGSIARSYRTAKTTMVVGKQRMPESRCYFYQDLMLPVLLDSLRGDWQANELARPLARLKAMDNN
GLLRRTLAAWFRHNVQPLATSKALFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEER
>Mature_384_residues
AGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERIGELHEGALLVLSQGRVVDIDDAVARHLHGVRQGINLP
LRLEGEIVGVIGLTGEPENLRKYGELVCMTAEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDLN
QPRVVAIVEVDSGQLGVDSAMAELQQLQNALTTPERNNLVAIVSLTEMVVLKPALNSFGRWDAEDHRKRVEQLITRMKEY
GQLRFRVSLGNYFTGPGSIARSYRTAKTTMVVGKQRMPESRCYFYQDLMLPVLLDSLRGDWQANELARPLARLKAMDNNG
LLRRTLAAWFRHNVQPLATSKALFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEER

Specific function: Seems to regulate the expression of the operons for the enzymes involved in D-galactarate, D-glucarate and D-glycerate utilization [H]

COG id: COG3835

COG function: function code KT; Sugar diacid utilization regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CdaR family [H]

Homologues:

Organism=Escherichia coli, GI87081694, Length=385, Percent_Identity=99.7402597402597, Blast_Score=781, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008599 [H]

Pfam domain/function: PF05651 Diacid_rec [H]

EC number: NA

Molecular weight: Translated: 43658; Mature: 43527

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERIGELHEGALLVLSQGRV
CCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCEECCCCHHHHHHHCCCEEEEEECCCE
VDIDDAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPENLRKYGELVCMTAEMMLEQSR
EECHHHHHHHHHHHHHCCCCCEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
LMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDLNQPRVVAIVEVDSGQLGVDS
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHH
AMAELQQLQNALTTPERNNLVAIVSLTEMVVLKPALNSFGRWDAEDHRKRVEQLITRMKE
HHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
YGQLRFRVSLGNYFTGPGSIARSYRTAKTTMVVGKQRMPESRCYFYQDLMLPVLLDSLRG
CCCEEEEEEECCEECCCHHHHHHHHHHHHHEEECHHCCCHHHHHHHHHHHHHHHHHHHCC
DWQANELARPLARLKAMDNNGLLRRTLAAWFRHNVQPLATSKALFIHRNTLEYRLNRISE
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHH
LTGLDLGNFDDRLLLYVALQLDEER
HHCCCCCCCCCCEEEEEEEEECCCC
>Mature Secondary Structure 
AGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERIGELHEGALLVLSQGRV
CCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCEECCCCHHHHHHHCCCEEEEEECCCE
VDIDDAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPENLRKYGELVCMTAEMMLEQSR
EECHHHHHHHHHHHHHCCCCCEEECCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
LMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDLNQPRVVAIVEVDSGQLGVDS
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHH
AMAELQQLQNALTTPERNNLVAIVSLTEMVVLKPALNSFGRWDAEDHRKRVEQLITRMKE
HHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
YGQLRFRVSLGNYFTGPGSIARSYRTAKTTMVVGKQRMPESRCYFYQDLMLPVLLDSLRG
CCCEEEEEEECCEECCCHHHHHHHHHHHHHEEECHHCCCHHHHHHHHHHHHHHHHHHHCC
DWQANELARPLARLKAMDNNGLLRRTLAAWFRHNVQPLATSKALFIHRNTLEYRLNRISE
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHH
LTGLDLGNFDDRLLLYVALQLDEER
HHCCCCCCCCCCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10762278 [H]