BacMap

Definition	Staphylococcus aureus subsp. aureus Mu3, complete genome.
Accession	NC_009782
Length	2,880,168

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The map label for this gene is yhxD [H]

Identifier: 156980643

GI number: 156980643

Start: 2453892

End: 2454773

Strand: Reverse

Name: yhxD [H]

Synonym: SAHV_2312

Alternate gene names: 156980643

Gene position: 2454773-2453892 (Counterclockwise)

Preceding gene: 156980644

Following gene: 156980642

Centisome position: 85.23

GC content: 39.23

Gene sequence:

>882_bases
ATGGCAACTCAAGATCCTAGAACAAAATTTAAAACAACGGAATATGAAAAACAAGAACAAGAGGTACCGGGTTTACAATC
TGAAATGACGCCAGCACCTGATTGTGGCGAAACGTCTTACCAAGGTCATCAACGCTTACAAGGCTATAAAATGTTAGTCA
CAGGTGGTGACTCAGCAATAGGGCGTGCAGCAGCAATTGCGTATGCTAAAGAAGGTGCAGATGTAGCGATTAACTATCTT
CCGAGTGAAGAACAAGATGCACAAGAAGTACGCCAAGTAATTGAAGAAAGTGGTCAAAAGGCAGTGTTAATTCCTGGTGA
TATAAGAGATGAGCAGTTCAACTATGACCTTGTTGAACAAGCATATCAACAATTAGGTGGCTTAGATAATGTTACTTTAG
TTGCTGGACATCAACAGTATCATGATGATATTCATGGATTTACAACTGAGGCATTTACAGAAACATTTGAAACGAATGTC
TATCCGCTATTTTGGACAGTTCAAAAAGCATTGGAATATTTAAAACCGGGTGCGTCAATTACAACGACATCATCTGTACA
AGGTTATAATCCTAGTCCTATTCTTCATGATTATGCCGCTTCAAAAGCAGCAATTATTTCATTAACTAAAAGTTTTTCAG
AAGAATTAGGACCAAAAGGAATTAGAGTGAACTGTGTAGCACCTGGTCCATTCTGGTCACCATTACAAATTTCTGGTGGG
CAACCTCAAAGTAAAATCCCAACATTTGGTCAAAAAACACCTTTAGGTCGTGCAGGTCAACCTGTTGAGTTATGTGGAAC
TTATGTGCTATTAGCGTCAGAGGAATCAAGTTATACAACTGGACAAGTGTTCGGTGTTAGCGGTGGAGTGCAAATAGATT
AG

Upstream 100 bases:

>100_bases
TTTTTATAAAGAAGAAAGTAATTTTTAGTGTAATCATGATTAAGTTCCTAGGAAGATTGGGTAAATAATAACCATTAAGC
GAATAAGGAGATGTTAAAAA

Downstream 100 bases:

>100_bases
GGTTGTATGAAGCTTTTAATTGAACAGCATAATATTAATTTAGTTACTTCAATCCATTAAATTAAAATGAATTGGTGAAG
TGTATTTTAAATAGTCGGTA

Product: hypothetical protein

Products: NA

Alternate protein names: ORFY [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MATQDPRTKFKTTEYEKQEQEVPGLQSEMTPAPDCGETSYQGHQRLQGYKMLVTGGDSAIGRAAAIAYAKEGADVAINYL
PSEEQDAQEVRQVIEESGQKAVLIPGDIRDEQFNYDLVEQAYQQLGGLDNVTLVAGHQQYHDDIHGFTTEAFTETFETNV
YPLFWTVQKALEYLKPGASITTTSSVQGYNPSPILHDYAASKAAIISLTKSFSEELGPKGIRVNCVAPGPFWSPLQISGG
QPQSKIPTFGQKTPLGRAGQPVELCGTYVLLASEESSYTTGQVFGVSGGVQID

Sequences:

>Translated_293_residues
MATQDPRTKFKTTEYEKQEQEVPGLQSEMTPAPDCGETSYQGHQRLQGYKMLVTGGDSAIGRAAAIAYAKEGADVAINYL
PSEEQDAQEVRQVIEESGQKAVLIPGDIRDEQFNYDLVEQAYQQLGGLDNVTLVAGHQQYHDDIHGFTTEAFTETFETNV
YPLFWTVQKALEYLKPGASITTTSSVQGYNPSPILHDYAASKAAIISLTKSFSEELGPKGIRVNCVAPGPFWSPLQISGG
QPQSKIPTFGQKTPLGRAGQPVELCGTYVLLASEESSYTTGQVFGVSGGVQID
>Mature_292_residues
ATQDPRTKFKTTEYEKQEQEVPGLQSEMTPAPDCGETSYQGHQRLQGYKMLVTGGDSAIGRAAAIAYAKEGADVAINYLP
SEEQDAQEVRQVIEESGQKAVLIPGDIRDEQFNYDLVEQAYQQLGGLDNVTLVAGHQQYHDDIHGFTTEAFTETFETNVY
PLFWTVQKALEYLKPGASITTTSSVQGYNPSPILHDYAASKAAIISLTKSFSEELGPKGIRVNCVAPGPFWSPLQISGGQ
PQSKIPTFGQKTPLGRAGQPVELCGTYVLLASEESSYTTGQVFGVSGGVQID

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=240, Percent_Identity=29.1666666666667, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI15277342, Length=263, Percent_Identity=30.4182509505703, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI5031737, Length=239, Percent_Identity=28.8702928870293, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=29.8701298701299, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=28.4046692607004, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI33667109, Length=180, Percent_Identity=31.1111111111111, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=26.6129032258064, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=26.7489711934156, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=25.7936507936508, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI32455239, Length=193, Percent_Identity=31.6062176165803, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI5031765, Length=193, Percent_Identity=31.6062176165803, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=29.6442687747036, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI4758504, Length=263, Percent_Identity=24.3346007604563, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=29.6875, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1789378, Length=286, Percent_Identity=60.1398601398601, Blast_Score=353, Evalue=6e-99,
Organism=Escherichia coli, GI2367175, Length=247, Percent_Identity=35.6275303643725, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1788459, Length=248, Percent_Identity=30.6451612903226, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=26.5060240963855, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=28.6259541984733, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI87082160, Length=247, Percent_Identity=27.5303643724696, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=25.2066115702479, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=30.5220883534137, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=29.4354838709677, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=25.4032258064516, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=27.6264591439689, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787545, Length=253, Percent_Identity=24.5059288537549, Blast_Score=64, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=33.0798479087452, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=29.5546558704453, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=30.5343511450382, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=31.8007662835249, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=28.3464566929134, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=30.0380228136882, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=28.2258064516129, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=28.6259541984733, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=30.0380228136882, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=29.5019157088123, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=27.2388059701493, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=28.7878787878788, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=27.4436090225564, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=26.9961977186312, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=27.6679841897233, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=254, Percent_Identity=27.1653543307087, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=258, Percent_Identity=25.1937984496124, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=26.4150943396226, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115534694, Length=246, Percent_Identity=26.4227642276423, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17536651, Length=254, Percent_Identity=25.1968503937008, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=256, Percent_Identity=28.125, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=23.9837398373984, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=271, Percent_Identity=27.6752767527675, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=252, Percent_Identity=26.984126984127, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=260, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=26.2172284644195, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=252, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=223, Percent_Identity=26.0089686098655, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=30.6772908366534, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=28.968253968254, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=30.8943089430894, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI28571526, Length=244, Percent_Identity=29.9180327868852, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24639444, Length=259, Percent_Identity=30.5019305019305, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24644337, Length=147, Percent_Identity=38.7755102040816, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=27.3092369477912, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI17737361, Length=259, Percent_Identity=28.1853281853282, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24643142, Length=254, Percent_Identity=29.1338582677165, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31797; Mature: 31665

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQDPRTKFKTTEYEKQEQEVPGLQSEMTPAPDCGETSYQGHQRLQGYKMLVTGGDSAI
CCCCCCCCCCCCCHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHCCCEEEEEECCCCHH
GRAAAIAYAKEGADVAINYLPSEEQDAQEVRQVIEESGQKAVLIPGDIRDEQFNYDLVEQ
HHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHH
AYQQLGGLDNVTLVAGHQQYHDDIHGFTTEAFTETFETNVYPLFWTVQKALEYLKPGASI
HHHHHCCCCCEEEEECCHHHHHHHHCCHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCE
TTTSSVQGYNPSPILHDYAASKAAIISLTKSFSEELGPKGIRVNCVAPGPFWSPLQISGG
EEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEECCC
QPQSKIPTFGQKTPLGRAGQPVELCGTYVLLASEESSYTTGQVFGVSGGVQID
CCCCCCCCCCCCCCCCCCCCCHHHHCEEEEEECCCCCCCCCEEEECCCCCEEC
>Mature Secondary Structure 
ATQDPRTKFKTTEYEKQEQEVPGLQSEMTPAPDCGETSYQGHQRLQGYKMLVTGGDSAI
CCCCCCCCCCCCHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHCCCEEEEEECCCCHH
GRAAAIAYAKEGADVAINYLPSEEQDAQEVRQVIEESGQKAVLIPGDIRDEQFNYDLVEQ
HHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHH
AYQQLGGLDNVTLVAGHQQYHDDIHGFTTEAFTETFETNVYPLFWTVQKALEYLKPGASI
HHHHHCCCCCEEEEECCHHHHHHHHCCHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCE
TTTSSVQGYNPSPILHDYAASKAAIISLTKSFSEELGPKGIRVNCVAPGPFWSPLQISGG
EEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEECCC
QPQSKIPTFGQKTPLGRAGQPVELCGTYVLLASEESSYTTGQVFGVSGGVQID
CCCCCCCCCCCCCCCCCCCCCHHHHCEEEEEECCCCCCCCCEEEECCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 8196543 [H]