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The map label for this gene is tdk [H]

Identifier: 156980434

GI number: 156980434

Start: 2247462

End: 2248061

Strand: Reverse

Name: tdk [H]

Synonym: SAHV_2103

Alternate gene names: 156980434

Gene position: 2248061-2247462 (Counterclockwise)

Preceding gene: 156980435

Following gene: 156980433

Centisome position: 78.05

GC content: 36.83

Gene sequence:

>600_bases
ATGTATGAAACTTACCATTCCGGTTGGATAGAATGTATTACAGGTAGTATGTTTAGCGGTAAATCCGAAGAACTAATAAG
ACGTCTAAGAAGGGGTATATACGCTAAACAAAAAGTCGTTGTATTTAAACCGGCGATTGATGATCGATATCATAAAGAAA
AAGTGGTCTCTCATAATGGTAATGCCATTGAAGCGATTAATATTTCTAAAGCAAGTGAAATTATGACGCACAACTTAACT
AATGTTGATGTTATAGGAATAGACGAAGTGCAATTTTTTGACGATGAAATTGTAAGTATAGTAGAAAAACTATCAGCAGA
TGGACACCGTGTTATTGTTGCTGGATTAGATATGGATTTTAGGGGCGAACCGTTCGAACCAATGCCTAAATTGATGGCTG
TCAGTGAACAAGTAACGAAACTTCAAGCAGTTTGTGCTGTTTGTGGTTCTTCATCTAGTAGAACGCAACGATTAATAAAT
GGTAAACCAGCTAAAATCGATGATCCGATTATCTTAGTAGGTGCCAATGAAAGTTATGAGCCACGTTGTCGCGCGCACCA
TATCGTAGCACCTAGTGATAATAATAAGGAGGAATTATAA

Upstream 100 bases:

>100_bases
GTTCATGTACAATATCGATATAATTATGAAAAAGACATTTATGAATATTTGAAATATGATATAATAAAGCGATTATGTTT
TGAAAAAGGTGGAACTCTCA

Downstream 100 bases:

>100_bases
GTGTTTGATCAATTAGATATTGTAGAAGAAAGATACGAACAGTTAAATGAACTGTTAAGTGACCCAGATGTTGTAAATGA
TTCAGATAAATTACGTAAAT

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MYETYHSGWIECITGSMFSGKSEELIRRLRRGIYAKQKVVVFKPAIDDRYHKEKVVSHNGNAIEAINISKASEIMTHNLT
NVDVIGIDEVQFFDDEIVSIVEKLSADGHRVIVAGLDMDFRGEPFEPMPKLMAVSEQVTKLQAVCAVCGSSSSRTQRLIN
GKPAKIDDPIILVGANESYEPRCRAHHIVAPSDNNKEEL

Sequences:

>Translated_199_residues
MYETYHSGWIECITGSMFSGKSEELIRRLRRGIYAKQKVVVFKPAIDDRYHKEKVVSHNGNAIEAINISKASEIMTHNLT
NVDVIGIDEVQFFDDEIVSIVEKLSADGHRVIVAGLDMDFRGEPFEPMPKLMAVSEQVTKLQAVCAVCGSSSSRTQRLIN
GKPAKIDDPIILVGANESYEPRCRAHHIVAPSDNNKEEL
>Mature_199_residues
MYETYHSGWIECITGSMFSGKSEELIRRLRRGIYAKQKVVVFKPAIDDRYHKEKVVSHNGNAIEAINISKASEIMTHNLT
NVDVIGIDEVQFFDDEIVSIVEKLSADGHRVIVAGLDMDFRGEPFEPMPKLMAVSEQVTKLQAVCAVCGSSSSRTQRLIN
GKPAKIDDPIILVGANESYEPRCRAHHIVAPSDNNKEEL

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Homo sapiens, GI164698438, Length=181, Percent_Identity=38.6740331491713, Blast_Score=108, Evalue=3e-24,
Organism=Escherichia coli, GI1787490, Length=182, Percent_Identity=29.1208791208791, Blast_Score=68, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17543396, Length=196, Percent_Identity=31.1224489795918, Blast_Score=96, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 22214; Mature: 22214

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00014 ER_TARGET ; PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYETYHSGWIECITGSMFSGKSEELIRRLRRGIYAKQKVVVFKPAIDDRYHKEKVVSHNG
CCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCC
NAIEAINISKASEIMTHNLTNVDVIGIDEVQFFDDEIVSIVEKLSADGHRVIVAGLDMDF
CEEEEEECCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
RGEPFEPMPKLMAVSEQVTKLQAVCAVCGSSSSRTQRLINGKPAKIDDPIILVGANESYE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEEEEECCCCCC
PRCRAHHIVAPSDNNKEEL
CCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MYETYHSGWIECITGSMFSGKSEELIRRLRRGIYAKQKVVVFKPAIDDRYHKEKVVSHNG
CCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCC
NAIEAINISKASEIMTHNLTNVDVIGIDEVQFFDDEIVSIVEKLSADGHRVIVAGLDMDF
CEEEEEECCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCC
RGEPFEPMPKLMAVSEQVTKLQAVCAVCGSSSSRTQRLINGKPAKIDDPIILVGANESYE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEEEEECCCCCC
PRCRAHHIVAPSDNNKEEL
CCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA