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The map label for this gene is alr [H]

Identifier: 156980386

GI number: 156980386

Start: 2199856

End: 2201004

Strand: Reverse

Name: alr [H]

Synonym: SAHV_2055

Alternate gene names: 156980386

Gene position: 2201004-2199856 (Counterclockwise)

Preceding gene: 156980387

Following gene: 156980385

Centisome position: 76.42

GC content: 36.03

Gene sequence:

>1149_bases
ATGTCGGATAAATATTATAGATCTGCGTATATGAATGTAGATTTAAACGCTGTTGCATCAAATTTCAAAGTATTCAGTAC
ATTGCATCCAAATAAAACAGTGATGGCTGTCGTTAAAGCCAATGCCTATGGACTAGGTAGTGTTAAAGTAGCACGTCATT
TAATGGAAAATGGCGCCACATTTTTTGCTGTAGCAACGTTAGATGAAGCGATAGAACTTAGAATGCATGGGATTACTGCT
AAAATTTTAGTCTTAGGTGTGTTACCAGCTAAAGATATTGATAAAGCGATACAACACAGAGTTGCCTTAACGGTTCCGTC
TAAACAGTGGTTGAAAGAAGCAATTAAAAACATTTCTGGTGAGCAAGAGAAAAAGTTATGGTTGCACATTAAATTAGATA
CAGGAATGGGACGTTTAGGTATTAAAGATACTAATACGTATCAAGAAGTGATTGAAATCATTCAACAATATGAGCAACTT
GTATTTGAAGGCGTGTTTACACACTTTGCCTGTGCTGACGAACCAGGAGATATGACAACTGAACAATATCAACGTTTTAA
AGATATGGTCAATGAAGCAATTAAACCTGAATATATACATTGTCAGAACTCAGCAGGCTCTCTATTAATGGATTGCCAAT
TCTGTAATGCAATAAGACCAGGAATTTCCCTTTATGGATATTATCCATCAGAGTATGTACAGCAAAAAGTTAAAGTACAC
CTTAAACCAAGTGTGCAATTAATTGCTAATGTAGTTCAAACAAAGACGCTACAAGCGGGTGAGTCTGTAAGTTATGGTGC
AACTTATACAGCTACTGACCCAACTACAATAGCTTTGTTACCTATTGGATATGCAGATGGCTATTTACGCATAATGCAAG
GTAGCTTTGTAAATGTAAATGGTCATCAATGCGAAGTTATTGGTCGCGTATGTATGGATCAGACAATTGTTAAAGTGCCA
GATCAAGTTAAAGCTGGAGATTCGGTGATTTTAATAGATAATCATAGAGAAAGTCCACAGTCGGTAGAGGTGGTAGCTGA
AAAGCAACATACTATTAATTATGAAGTGCTTTGTAACTTGTCGAGACGTTTGCCGCGAATCTATCATGATGGTGATCAAC
GTTTTGTAACAAATGAATTGTTAAAATAA

Upstream 100 bases:

>100_bases
TGAGCCAAGTTGTTTTAGAAAAGTCAGCATTTTAAATTTGTTATACAATGATAATTAAGATCTAGTTTTAAAACGTGTGG
GAATTACAGGAGGAAGTAAT

Downstream 100 bases:

>100_bases
TATGGTCAGTGCATATAAAATTTGTTATCATTAGAGTAATTAAAGGTCATTTAATAACTTTTGGAATCAATTGGAGGTTC
TCATATGTTATCTTTTAGTC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MSDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGATFFAVATLDEAIELRMHGITA
KILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISGEQEKKLWLHIKLDTGMGRLGIKDTNTYQEVIEIIQQYEQL
VFEGVFTHFACADEPGDMTTEQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVH
LKPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVNGHQCEVIGRVCMDQTIVKVP
DQVKAGDSVILIDNHRESPQSVEVVAEKQHTINYEVLCNLSRRLPRIYHDGDQRFVTNELLK

Sequences:

>Translated_382_residues
MSDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGATFFAVATLDEAIELRMHGITA
KILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISGEQEKKLWLHIKLDTGMGRLGIKDTNTYQEVIEIIQQYEQL
VFEGVFTHFACADEPGDMTTEQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVH
LKPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVNGHQCEVIGRVCMDQTIVKVP
DQVKAGDSVILIDNHRESPQSVEVVAEKQHTINYEVLCNLSRRLPRIYHDGDQRFVTNELLK
>Mature_381_residues
SDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGATFFAVATLDEAIELRMHGITAK
ILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISGEQEKKLWLHIKLDTGMGRLGIKDTNTYQEVIEIIQQYEQLV
FEGVFTHFACADEPGDMTTEQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVHL
KPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVNGHQCEVIGRVCMDQTIVKVPD
QVKAGDSVILIDNHRESPQSVEVVAEKQHTINYEVLCNLSRRLPRIYHDGDQRFVTNELLK

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=370, Percent_Identity=32.7027027027027, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1787439, Length=369, Percent_Identity=32.2493224932249, Blast_Score=148, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 42810; Mature: 42679

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGAT
CCCCCEEHEEECCCHHHHHCCCEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHCCCE
FFAVATLDEAIELRMHGITAKILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISG
EEEEEEHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHCEEEEECCCHHHHHHHHHCCCC
EQEKKLWLHIKLDTGMGRLGIKDTNTYQEVIEIIQQYEQLVFEGVFTHFACADEPGDMTT
CCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
EQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVH
HHHHHHHHHHHHCCCCCEEEECCCCCCEEEEHHHHHHHCCCCEEEEECCHHHHHHHHEEE
LKPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVN
ECCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEEECCCCCEEEEEECCEEECC
GHQCEVIGRVCMDQTIVKVPDQVKAGDSVILIDNHRESPQSVEVVAEKQHTINYEVLCNL
CCCHHHHHHHHHCCHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHEEEH
SRRLPRIYHDGDQRFVTNELLK
HHCCCCEEECCCCHHHHHHHCC
>Mature Secondary Structure 
SDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVARHLMENGAT
CCCCEEHEEECCCHHHHHCCCEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHCCCE
FFAVATLDEAIELRMHGITAKILVLGVLPAKDIDKAIQHRVALTVPSKQWLKEAIKNISG
EEEEEEHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHCEEEEECCCHHHHHHHHHCCCC
EQEKKLWLHIKLDTGMGRLGIKDTNTYQEVIEIIQQYEQLVFEGVFTHFACADEPGDMTT
CCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
EQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAIRPGISLYGYYPSEYVQQKVKVH
HHHHHHHHHHHHCCCCCEEEECCCCCCEEEEHHHHHHHCCCCEEEEECCHHHHHHHHEEE
LKPSVQLIANVVQTKTLQAGESVSYGATYTATDPTTIALLPIGYADGYLRIMQGSFVNVN
ECCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEEECCCCCEEEEEECCEEECC
GHQCEVIGRVCMDQTIVKVPDQVKAGDSVILIDNHRESPQSVEVVAEKQHTINYEVLCNL
CCCHHHHHHHHHCCHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCHHHEEEH
SRRLPRIYHDGDQRFVTNELLK
HHCCCCEEECCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9756984 [H]