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The map label for this gene is scn

Identifier: 156980258

GI number: 156980258

Start: 2085714

End: 2086064

Strand: Reverse

Name: scn

Synonym: SAHV_1927

Alternate gene names: 156980258

Gene position: 2086064-2085714 (Counterclockwise)

Preceding gene: 156980259

Following gene: 156980254

Centisome position: 72.43

GC content: 28.77

Gene sequence:

>351_bases
ATGAAAATTAGAAAATCTATACTTGCGGGAACTTTAGCAATCGTTTTAGCATCACCACTAGTAACTAATCTAGATAAAAA
TGAGGCACAAGCTAGCACAAGCTTGCCAACATCGAATGAATATCAAAACGAAAAGTTAGCTAATGAATTAAAATCGTTAT
TAGATGAACTAAATGTTAATGAATTAGCTACTGGAAGTTTAAACACTTATTATAAGCGAACTATAAAAATTTCAGGTCAA
AAAGCAATGTATGCTCTTAAGTCAAAAGACTTTAAGAAAATGTCAGAAGCAAAATATCAACTTCAAAAGATTTATAATGA
AATTGACGAAGCACTAAAAAGTAAATATTAA

Upstream 100 bases:

>100_bases
CATTTAATAAGAAGATCTATATAGTTAATGAATAATTAATGTACTTTTTTTTAGTTAGTCATTAAAATAAATTAGTACTA
ATTACTAAGGAGAATAAAAA

Downstream 100 bases:

>100_bases
AAAACCACCCGTAAAAGGGTGGTTTTAATTTTCTAGATAATATAAAAGTGTTCATAAATAAAACAGTATAGGTAAACAAT
AAAGTATTGAAAAAAGTAAG

Product: hypothetical protein

Products: NA

Alternate protein names: SCIN

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MKIRKSILAGTLAIVLASPLVTNLDKNEAQASTSLPTSNEYQNEKLANELKSLLDELNVNELATGSLNTYYKRTIKISGQ
KAMYALKSKDFKKMSEAKYQLQKIYNEIDEALKSKY

Sequences:

>Translated_116_residues
MKIRKSILAGTLAIVLASPLVTNLDKNEAQASTSLPTSNEYQNEKLANELKSLLDELNVNELATGSLNTYYKRTIKISGQ
KAMYALKSKDFKKMSEAKYQLQKIYNEIDEALKSKY
>Mature_116_residues
MKIRKSILAGTLAIVLASPLVTNLDKNEAQASTSLPTSNEYQNEKLANELKSLLDELNVNELATGSLNTYYKRTIKISGQ
KAMYALKSKDFKKMSEAKYQLQKIYNEIDEALKSKY

Specific function: Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inacti

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SCIN family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SCIN_STAA1 (A7X482)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442517.1
- EnsemblBacteria:   EBSTAT00000004064
- GeneID:   5560088
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1927
- GeneTree:   EBGT00050000025147
- HOGENOM:   HBG215941
- ProtClustDB:   CLSK884496
- BioCyc:   SAUR418127:SAHV_1927-MONOMER
- GO:   GO:0009405
- InterPro:   IPR021612

Pfam domain/function: PF11546 CompInhib_SCIN

EC number: NA

Molecular weight: Translated: 13067; Mature: 13067

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRKSILAGTLAIVLASPLVTNLDKNEAQASTSLPTSNEYQNEKLANELKSLLDELNVN
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCH
ELATGSLNTYYKRTIKISGQKAMYALKSKDFKKMSEAKYQLQKIYNEIDEALKSKY
HHCCCCHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIRKSILAGTLAIVLASPLVTNLDKNEAQASTSLPTSNEYQNEKLANELKSLLDELNVN
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCH
ELATGSLNTYYKRTIKISGQKAMYALKSKDFKKMSEAKYQLQKIYNEIDEALKSKY
HHCCCCHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA