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The map label for this gene is nqo14 [H]

Identifier: 156937936

GI number: 156937936

Start: 1024445

End: 1025758

Strand: Direct

Name: nqo14 [H]

Synonym: Igni_1148

Alternate gene names: 156937936

Gene position: 1024445-1025758 (Clockwise)

Preceding gene: 156937935

Following gene: 156937937

Centisome position: 78.95

GC content: 59.67

Gene sequence:

>1314_bases
ATGGCCTCCCTTCTGTTAGACTTGCTCGCCATACTCCAAGCGCTCTTGTTGCCGGCCCAGCTGTCCAAGTACTTGTCGGC
CTTCTTGCTAACCCTCAGCATATTCTTCGCCAGCGGGAAGGTCGGCAGCATAGTGGGCGACTACTACACCCAGATGGGCA
TGATGGCCGTCGCAGTGCCGTCAATAATAACGCTGCTCTTCCACACCCGGCCGCAGAGGCACTTCATCTTGCTAGTTACC
TTAGTCACGGTCGCCGGCTACTTGGTGGCGGCCTCGAGGAACTTGGCGACCTTAGCGGTCTCCTTGGAGGCCCTCTCGCT
CTCCGCAGCTGCCATAGCCTTCTACCCGGCCTCTAAAGACAAGATAAGGGTACTGAGCACTTACTTGGTGTTCAGCGTGT
TCGCCGCGGTACTGCTGTTCTCCGGGCTGGCGTTCTACTTCGCCGGCACCAACACGTTCAGCTTGGTAGAGTTCACCCAG
ACCTCCACTGCCATAGTCGGGCTGACGTTGATACTGGCCTCAATAATGGTGAAGGTAGCGTTAGCGCCCATGCACGCTTG
GGCGGTGGACGTCTACTCCTTGAGCAGCACCAGCGCGGCCTTGTACTTGTCCAACGCAGTGAAGGCCAGCGCCTTCGTGG
CGCTGGGCATACTCGCTGCCGGCCCGCTGGAGATGGCGATGTCCGTGGGCTACTGGCAAGTGTTGGTGCCGGTCATGCTC
TTGGCAGTGGCTTCAATAGCAGTGGCGGCGGGGGGCATGGCCCTCAGCTCCGAAACCAAGAGGTTGTTGGCCTTCTCCAG
CATAGCCCACGCGGGCTTCGCTACCTTGGCCCTAGCGGCCCCGGGCCCGACAGCTGCAGCTATACTGGCCTACTACGCCT
TGGTGTACTCCTTGTCTAACACCATAGGCTTCTCCGCGGTTCTGCTACTGAAGAAGGAGGGCGAGGCGAGCTTGAGTGAG
CTTAGCTTGCTGTACAAGAGACCCTTAACTGCGCTGGCCTTCGCAATAGGGATAATATCGCTCTTGGGCATCCCCCCGAC
TGCAGGGTTCAACGCCAAGCTCTTCGCGCTGTTCAACTTACTCACGTCGACCAACTTGCCCAACTGGTACGCCCTAGCTA
TAGCCCTAGCGGCCGTGGTCTTCACGGCGGCCACGGGATACGGCTACGCCAAAGCCATAGCTGCCGTAGCCAAGAGGCCG
GAGGGCGAGCCCGAGGCGAACGCCGGGCTGGAGCTGATGATGTGGTTCATGGCGTTCGTGGTACTTCTCTTGTACTTCTA
CCCAGCGCTGCCCGTTCCCACGGCCTTGGGTTGA

Upstream 100 bases:

>100_bases
GAATTGAAGGTGCCATGTTAATTGCCTTGGTTACCCTCTTCAACTACGTGTACCGCGACGTGGACGTCATAAAGATTAAG
GAAGGAGGTGAGGAGGAGTG

Downstream 100 bases:

>100_bases
TGCTCCATGTTAAACAAGTTTTTAAAGTTGTTTAGCAAGCTGCTCTCCACCCTGTACCAAGCTTCCCCCGAAGGGGGGAA
GGTGGTTAAGGTCTACAGCG

Product: NADH/ubiquinone/plastoquinone (complex I)

Products: NA

Alternate protein names: NADH dehydrogenase I chain 14; NDH-1 subunit 14 [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MASLLLDLLAILQALLLPAQLSKYLSAFLLTLSIFFASGKVGSIVGDYYTQMGMMAVAVPSIITLLFHTRPQRHFILLVT
LVTVAGYLVAASRNLATLAVSLEALSLSAAAIAFYPASKDKIRVLSTYLVFSVFAAVLLFSGLAFYFAGTNTFSLVEFTQ
TSTAIVGLTLILASIMVKVALAPMHAWAVDVYSLSSTSAALYLSNAVKASAFVALGILAAGPLEMAMSVGYWQVLVPVML
LAVASIAVAAGGMALSSETKRLLAFSSIAHAGFATLALAAPGPTAAAILAYYALVYSLSNTIGFSAVLLLKKEGEASLSE
LSLLYKRPLTALAFAIGIISLLGIPPTAGFNAKLFALFNLLTSTNLPNWYALAIALAAVVFTAATGYGYAKAIAAVAKRP
EGEPEANAGLELMMWFMAFVVLLLYFYPALPVPTALG

Sequences:

>Translated_437_residues
MASLLLDLLAILQALLLPAQLSKYLSAFLLTLSIFFASGKVGSIVGDYYTQMGMMAVAVPSIITLLFHTRPQRHFILLVT
LVTVAGYLVAASRNLATLAVSLEALSLSAAAIAFYPASKDKIRVLSTYLVFSVFAAVLLFSGLAFYFAGTNTFSLVEFTQ
TSTAIVGLTLILASIMVKVALAPMHAWAVDVYSLSSTSAALYLSNAVKASAFVALGILAAGPLEMAMSVGYWQVLVPVML
LAVASIAVAAGGMALSSETKRLLAFSSIAHAGFATLALAAPGPTAAAILAYYALVYSLSNTIGFSAVLLLKKEGEASLSE
LSLLYKRPLTALAFAIGIISLLGIPPTAGFNAKLFALFNLLTSTNLPNWYALAIALAAVVFTAATGYGYAKAIAAVAKRP
EGEPEANAGLELMMWFMAFVVLLLYFYPALPVPTALG
>Mature_436_residues
ASLLLDLLAILQALLLPAQLSKYLSAFLLTLSIFFASGKVGSIVGDYYTQMGMMAVAVPSIITLLFHTRPQRHFILLVTL
VTVAGYLVAASRNLATLAVSLEALSLSAAAIAFYPASKDKIRVLSTYLVFSVFAAVLLFSGLAFYFAGTNTFSLVEFTQT
STAIVGLTLILASIMVKVALAPMHAWAVDVYSLSSTSAALYLSNAVKASAFVALGILAAGPLEMAMSVGYWQVLVPVMLL
AVASIAVAAGGMALSSETKRLLAFSSIAHAGFATLALAAPGPTAAAILAYYALVYSLSNTIGFSAVLLLKKEGEASLSEL
SLLYKRPLTALAFAIGIISLLGIPPTAGFNAKLFALFNLLTSTNLPNWYALAIALAAVVFTAATGYGYAKAIAAVAKRPE
GEPEANAGLELMMWFMAFVVLLLYFYPALPVPTALG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is menaquinone. Couples the redox reaction to proton translocation (for every

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Escherichia coli, GI145693160, Length=308, Percent_Identity=26.9480519480519, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 45775; Mature: 45644

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLLLDLLAILQALLLPAQLSKYLSAFLLTLSIFFASGKVGSIVGDYYTQMGMMAVAVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
SIITLLFHTRPQRHFILLVTLVTVAGYLVAASRNLATLAVSLEALSLSAAAIAFYPASKD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEECCCCC
KIRVLSTYLVFSVFAAVLLFSGLAFYFAGTNTFSLVEFTQTSTAIVGLTLILASIMVKVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHH
LAPMHAWAVDVYSLSSTSAALYLSNAVKASAFVALGILAAGPLEMAMSVGYWQVLVPVML
HHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LAVASIAVAAGGMALSSETKRLLAFSSIAHAGFATLALAAPGPTAAAILAYYALVYSLSN
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHEEEECCCCHHHHHHHHHHHHHHHHH
TIGFSAVLLLKKEGEASLSELSLLYKRPLTALAFAIGIISLLGIPPTAGFNAKLFALFNL
HHCHHEEEEEECCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LTSTNLPNWYALAIALAAVVFTAATGYGYAKAIAAVAKRPEGEPEANAGLELMMWFMAFV
HHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
VLLLYFYPALPVPTALG
HHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ASLLLDLLAILQALLLPAQLSKYLSAFLLTLSIFFASGKVGSIVGDYYTQMGMMAVAVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
SIITLLFHTRPQRHFILLVTLVTVAGYLVAASRNLATLAVSLEALSLSAAAIAFYPASKD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEECCCCC
KIRVLSTYLVFSVFAAVLLFSGLAFYFAGTNTFSLVEFTQTSTAIVGLTLILASIMVKVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHH
LAPMHAWAVDVYSLSSTSAALYLSNAVKASAFVALGILAAGPLEMAMSVGYWQVLVPVML
HHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LAVASIAVAAGGMALSSETKRLLAFSSIAHAGFATLALAAPGPTAAAILAYYALVYSLSN
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCHHHEEEECCCCHHHHHHHHHHHHHHHHH
TIGFSAVLLLKKEGEASLSELSLLYKRPLTALAFAIGIISLLGIPPTAGFNAKLFALFNL
HHCHHEEEEEECCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LTSTNLPNWYALAIALAAVVFTAATGYGYAKAIAAVAKRPEGEPEANAGLELMMWFMAFV
HHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
VLLLYFYPALPVPTALG
HHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9020134 [H]