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The map label for this gene is guaB [C]

Identifier: 156937882

GI number: 156937882

Start: 976147

End: 976578

Strand: Direct

Name: guaB [C]

Synonym: Igni_1094

Alternate gene names: 156937882

Gene position: 976147-976578 (Clockwise)

Preceding gene: 156937881

Following gene: 156937885

Centisome position: 75.23

GC content: 57.41

Gene sequence:

>432_bases
GTGCGCCCGATTACGGTCGCGGACGTCATGTCCAAGCCCGTGGTGGTGATAGGGGTCAACAACACCTTGAGGGAAGCGGC
AAAGGAGATGATGGATAAGGGCGTGGGGAGCTTGGTCGTGGTGGACGAGAAGGGGGACGTCGTGGGAATAATAACCGAGA
GGGACGTGGTGAGGGCGGTAGCAGAGGGGAAGGACTTGAACGCGCCGGTCTCAGAGGTCATGACTCCCGACGTGCTCACC
GTGTCTCCGGAGACCAGCGTGCTCAAAGCTATAGAGACGATGAAGATGCACAACGTCCGCCACTTGCCCGTAGCTTCCGA
CGACGAAATAGTGGGGATGGTCTCGTTAAAGGACTTAGCCTTCGCGGTCGCTGCCGAGATGATACTAAAGAGGATATACG
AGATGTTGAAGGAGGAGCTCAGCGAGCTCTGA

Upstream 100 bases:

>100_bases
GCCTTGGGCCTCGAACGCCTCGGCCAGCTCTTTCAAGTCGAAGCGCAACGCGCTCTCCCCATATAACCTCCGGCCCGGTC
GTGAAAACCGGTGGAAGAGG

Downstream 100 bases:

>100_bases
GGAGGGGGGCCAGCGACAAGAACGCCGGGAGCCACGCCAAGGTCAAGGTTATTACGGACTTAGTAACGAGCTTGGTGTCG
TAACCGTACGCGTAAGCTAG

Product: signal-transduction protein

Products: H+; Nicotinamide adenine dinucleotide - reduced; Xanthosine 5'-phosphate [C]

Alternate protein names: ORF3 [H]

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MRPITVADVMSKPVVVIGVNNTLREAAKEMMDKGVGSLVVVDEKGDVVGIITERDVVRAVAEGKDLNAPVSEVMTPDVLT
VSPETSVLKAIETMKMHNVRHLPVASDDEIVGMVSLKDLAFAVAAEMILKRIYEMLKEELSEL

Sequences:

>Translated_143_residues
MRPITVADVMSKPVVVIGVNNTLREAAKEMMDKGVGSLVVVDEKGDVVGIITERDVVRAVAEGKDLNAPVSEVMTPDVLT
VSPETSVLKAIETMKMHNVRHLPVASDDEIVGMVSLKDLAFAVAAEMILKRIYEMLKEELSEL
>Mature_143_residues
MRPITVADVMSKPVVVIGVNNTLREAAKEMMDKGVGSLVVVDEKGDVVGIITERDVVRAVAEGKDLNAPVSEVMTPDVLT
VSPETSVLKAIETMKMHNVRHLPVASDDEIVGMVSLKDLAFAVAAEMILKRIYEMLKEELSEL

Specific function: GMP biosynthesis from IMP; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

None

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644 [H]

Pfam domain/function: PF00571 CBS [H]

EC number: 1.1.1.205 [C]

Molecular weight: Translated: 15529; Mature: 15529

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.0 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPITVADVMSKPVVVIGVNNTLREAAKEMMDKGVGSLVVVDEKGDVVGIITERDVVRAV
CCCCCHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECHHHHHHH
AEGKDLNAPVSEVMTPDVLTVSPETSVLKAIETMKMHNVRHLPVASDDEIVGMVSLKDLA
HCCCCCCCCHHHHCCCCEEEECCCHHHHHHHHHHHHCCCEECCCCCCCCEEEEHHHHHHH
FAVAAEMILKRIYEMLKEELSEL
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRPITVADVMSKPVVVIGVNNTLREAAKEMMDKGVGSLVVVDEKGDVVGIITERDVVRAV
CCCCCHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECHHHHHHH
AEGKDLNAPVSEVMTPDVLTVSPETSVLKAIETMKMHNVRHLPVASDDEIVGMVSLKDLA
HCCCCCCCCHHHHCCCCEEEECCCHHHHHHHHHHHHCCCEECCCCCCCCEEEEHHHHHHH
FAVAAEMILKRIYEMLKEELSEL
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; IMP; Nicotinamide adenine dinucleotide [C]

Specific reaction: H2O + IMP + Nicotinamide adenine dinucleotide --> H+ + Nicotinamide adenine dinucleotide - reduced + Xanthosine 5'-phosphate [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA