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The map label for this gene is 156937219

Identifier: 156937219

GI number: 156937219

Start: 378551

End: 379288

Strand: Reverse

Name: 156937219

Synonym: Igni_0425

Alternate gene names: NA

Gene position: 379288-378551 (Counterclockwise)

Preceding gene: 156937220

Following gene: 156937218

Centisome position: 29.23

GC content: 62.06

Gene sequence:

>738_bases
ATGGGGGCGTACGACGAGCTGATGAAGAGAAGGGGGAGGGCGCTCCTCCCGCTGCTGGACCCCGACAAGGTGATCTCCGA
GGAGGACTATTACGAAAGGGCCGTTAAGGCCTTGTGCGAGTACGCCGCCACCTTCTTGGTGGGCGGGAGCACCGGAGTGG
GCCAGATAGAGACCGAGAAGACGGTCGCGCTCGTGAAGAAGAACTGCGACAAGCCCGTCACGGTCTTCCCCGGGAGCCCT
TGCCAAGTCGCCCCTTCGGCGGACGCCATACTTTTCATGAGCCTGCTCAACAGCACCAACCGGAAGTACTTGATAGACTA
CCAGTTGGAGGGCTCTTTGTTGGTGTATAGGTACGGCTTGGAGGCCATACCTACGGCCTACATAATCGTAGGCGAGGGCG
GCACCGCGGGCTGGGTGGGGGAGGCAAAGGCAATACCCCCAGAGAAGCCGGAACTTTTGAGCATGTACGTGCTAGCTGCG
AAGTACTTGGGCTTCAAGGTAGTTTACCTAGAGGCGGGGAGCGGGGTCAAGAGGAGCGTGCCCCCCGAGGCGGTGAGGCT
GGCCAAGAAGCTGTTGGGGGAGGAGGTGATATTGATAGTAGGCGGGGGCATAAAGGACGAGGAGGTGGCGGCCGAGATCC
TCCGCGCCGGGGCCGACGGGGTGGTGGTGGGCACCGTGGTGGAAAGGGACCTAAGCGCGGCCGAGAGGATAGCCCGAAGG
GTGGCGGGTTGGACCTAG

Upstream 100 bases:

>100_bases
GCCCCATAATCGATAGGGCCGTCATATACGGCCGCTTCATAGACAAGTTCTACGCAGGTGAGATAAAGGTCCCCGAGGGC
GGCGAGGAAGAGGAGTGAGG

Downstream 100 bases:

>100_bases
AGGACGCGATCAAGTTCTTATTAGAGAAAGGCTTGAACAAGGACCAGATAATCAGCTTGGTCCTCCCCTTCCTCACCGTT
AGGAAGGGCCTAAGCTTGGA

Product: geranylgeranylglyceryl phosphate synthase-like protein

Products: NA

Alternate protein names: GGGP synthase; GGGPS; (S)-3-O-geranylgeranylglyceryl phosphate synthase; Phosphoglycerol geranylgeranyltransferase

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MGAYDELMKRRGRALLPLLDPDKVISEEDYYERAVKALCEYAATFLVGGSTGVGQIETEKTVALVKKNCDKPVTVFPGSP
CQVAPSADAILFMSLLNSTNRKYLIDYQLEGSLLVYRYGLEAIPTAYIIVGEGGTAGWVGEAKAIPPEKPELLSMYVLAA
KYLGFKVVYLEAGSGVKRSVPPEAVRLAKKLLGEEVILIVGGGIKDEEVAAEILRAGADGVVVGTVVERDLSAAERIARR
VAGWT

Sequences:

>Translated_245_residues
MGAYDELMKRRGRALLPLLDPDKVISEEDYYERAVKALCEYAATFLVGGSTGVGQIETEKTVALVKKNCDKPVTVFPGSP
CQVAPSADAILFMSLLNSTNRKYLIDYQLEGSLLVYRYGLEAIPTAYIIVGEGGTAGWVGEAKAIPPEKPELLSMYVLAA
KYLGFKVVYLEAGSGVKRSVPPEAVRLAKKLLGEEVILIVGGGIKDEEVAAEILRAGADGVVVGTVVERDLSAAERIARR
VAGWT
>Mature_244_residues
GAYDELMKRRGRALLPLLDPDKVISEEDYYERAVKALCEYAATFLVGGSTGVGQIETEKTVALVKKNCDKPVTVFPGSPC
QVAPSADAILFMSLLNSTNRKYLIDYQLEGSLLVYRYGLEAIPTAYIIVGEGGTAGWVGEAKAIPPEKPELLSMYVLAAK
YLGFKVVYLEAGSGVKRSVPPEAVRLAKKLLGEEVILIVGGGIKDEEVAAEILRAGADGVVVGTVVERDLSAAERIARRV
AGWT

Specific function: Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membr

COG id: COG1646

COG function: function code R; Predicted phosphate-binding enzymes, TIM-barrel fold

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GGGP synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GGGPS_IGNH4 (A8A9K6)

Other databases:

- EMBL:   CP000816
- RefSeq:   YP_001435015.1
- ProteinModelPortal:   A8A9K6
- SMR:   A8A9K6
- STRING:   A8A9K6
- GeneID:   5562959
- GenomeReviews:   CP000816_GR
- KEGG:   iho:Igni_0425
- eggNOG:   arNOG05493
- HOGENOM:   HBG313841
- OMA:   ADAIFFM
- ProtClustDB:   PRK04169
- BioCyc:   IHOS453591:IGNI_0425-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00112
- InterPro:   IPR008205
- InterPro:   IPR010946
- Gene3D:   G3DSA:3.20.20.390
- TIGRFAMs:   TIGR01769
- TIGRFAMs:   TIGR01768

Pfam domain/function: PF01884 PcrB

EC number: =2.5.1.41

Molecular weight: Translated: 26325; Mature: 26194

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: BINDING 203-203

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAYDELMKRRGRALLPLLDPDKVISEEDYYERAVKALCEYAATFLVGGSTGVGQIETEK
CCHHHHHHHHCCCEECCCCCCHHHCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHH
TVALVKKNCDKPVTVFPGSPCQVAPSADAILFMSLLNSTNRKYLIDYQLEGSLLVYRYGL
HHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCEEEEECCC
EAIPTAYIIVGEGGTAGWVGEAKAIPPEKPELLSMYVLAAKYLGFKVVYLEAGSGVKRSV
CCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEEECCCCCCCCC
PPEAVRLAKKLLGEEVILIVGGGIKDEEVAAEILRAGADGVVVGTVVERDLSAAERIARR
CHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHH
VAGWT
HCCCC
>Mature Secondary Structure 
GAYDELMKRRGRALLPLLDPDKVISEEDYYERAVKALCEYAATFLVGGSTGVGQIETEK
CHHHHHHHHCCCEECCCCCCHHHCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHH
TVALVKKNCDKPVTVFPGSPCQVAPSADAILFMSLLNSTNRKYLIDYQLEGSLLVYRYGL
HHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCEEEEECCC
EAIPTAYIIVGEGGTAGWVGEAKAIPPEKPELLSMYVLAAKYLGFKVVYLEAGSGVKRSV
CCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEEECCCCCCCCC
PPEAVRLAKKLLGEEVILIVGGGIKDEEVAAEILRAGADGVVVGTVVERDLSAAERIARR
CHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHH
VAGWT
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA