Click here to switch to the map view.

The map label for this gene is norA [H]

Identifier: 156937185

GI number: 156937185

Start: 343917

End: 345161

Strand: Reverse

Name: norA [H]

Synonym: Igni_0391

Alternate gene names: 156937185

Gene position: 345161-343917 (Counterclockwise)

Preceding gene: 156937188

Following gene: 156937183

Centisome position: 26.6

GC content: 54.54

Gene sequence:

>1245_bases
TTGTGGACGAAGCTGGTCGCCCTTTCTGCGATAATCTCGATAACGTTTTCGGCCTCTAACGTGGCTTTACCGTACTTCTT
GATGTACTTGAAAGGAGAACTAAAAACGCTGAACGCAGAGCTGCTCAACGCTAGCAAGGTCGCTTTGGAGTTCGGAGCGC
TCACGTCAACCTTCATGGGTACCAGGGTTGTCATTGCATTCCTCTCCGGCTACATAGCGGAAAGGATAGGAATGAAGAGG
TCAGTGGTAGTAGGCTTGATATTGTACCTTGTCAGCGGAATATGGTTAATAGTTACGGAGAACTACTGGGAAGTTTTGGT
ATCCAGAGCCCTACAAGGGGTGGCTTCGGCGATGGTGTGGCCGGTGGCGGAGTCCATGATAGTGGAGTTCGCCGGCGGGA
AGAAGACGAGGGCTTTGATGCTCTACGTCATGGCGTTTAACGTCGGCATGATCTTGGGGCCCGCGGTAGGGGGAGCGGCG
CTCCAAGCGTCTTCCTCGCTGCCCCTCCCCGTGGCGGTAAGGGTCCCCTTCGCGCTCCTCCCCTTGGGCGCGCTGGCGGG
CTTGCTCTTAATCTTCAAGCTGCCGGACGTGAGGTATAAAACTAAAATGAAGGTGAGGGAGCTCCACGCCAAGATAAAGT
CGGCGCTTTACGTTTTCTTCTTCAACGCCTTTGCCAACGGCTTTTCTGCCGGAATATTTATGAGCGTATTGATAATATAC
ATAATGCAGTACGTAACCTCCGTGCCAATAAAGCTGTCCTCGCTGGTGGCGCTCAGCGGCCTTTTGGGGATGGCCCTCGC
CTCTCCCTTGATGAAGAGGCTCGATGAATTTGACTTTACGAATAAGTTGAAAGTAGCTATAGGTTTAGGGCTGTTGCACA
AGCTCGCGTTAGCTGCGGTGGGCCTCACGAAAAGTTACTTTATCCTCCTAGCTATACTGACTGTACAAAACTTCGCGATA
ACTGTAGTAATACCCCTCATAAGGAGTTTGGTAAGCGACTTGGTCCCTAGGGAGTTGACCGCTAAGGTGTTCGGCATGCA
GCAAGCTTACTTCAACTTGGGCATGATAGTAGGCCCCTTGGTCGGGGCCGCGCTCTACAAGTGGTTGGAGGCCTCCGGCG
TCGGAGGGGGGTTGGCCTTCCCCGTGGCGGCGGCGCTGGGCGCGGCGGGGGTCCTCACGTTATTACGCGTGGACGGGCGC
GAGGTGGAGGGGATGAAGGGGGAGCCCGTTAAAGCTGAGGGGTGA

Upstream 100 bases:

>100_bases
GGTAACCTTCTTCACTTCCTTAGCCCAGAGGGCTTACATCCAGCGGTTATTTCTGTTCACACAATAAGGGCCCCGGGCGG
CCGGGCCTAGGTAAGGGGGC

Downstream 100 bases:

>100_bases
CGAGGAGAACCCCCGTCAGACCCCTTCCGGCCACGAGGCCCACTCCGGCAACCTCTTGCCCATGGCCGCCCTCACGTAGG
CTTCCCTCAGCTCCGCCCAC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MWTKLVALSAIISITFSASNVALPYFLMYLKGELKTLNAELLNASKVALEFGALTSTFMGTRVVIAFLSGYIAERIGMKR
SVVVGLILYLVSGIWLIVTENYWEVLVSRALQGVASAMVWPVAESMIVEFAGGKKTRALMLYVMAFNVGMILGPAVGGAA
LQASSSLPLPVAVRVPFALLPLGALAGLLLIFKLPDVRYKTKMKVRELHAKIKSALYVFFFNAFANGFSAGIFMSVLIIY
IMQYVTSVPIKLSSLVALSGLLGMALASPLMKRLDEFDFTNKLKVAIGLGLLHKLALAAVGLTKSYFILLAILTVQNFAI
TVVIPLIRSLVSDLVPRELTAKVFGMQQAYFNLGMIVGPLVGAALYKWLEASGVGGGLAFPVAAALGAAGVLTLLRVDGR
EVEGMKGEPVKAEG

Sequences:

>Translated_414_residues
MWTKLVALSAIISITFSASNVALPYFLMYLKGELKTLNAELLNASKVALEFGALTSTFMGTRVVIAFLSGYIAERIGMKR
SVVVGLILYLVSGIWLIVTENYWEVLVSRALQGVASAMVWPVAESMIVEFAGGKKTRALMLYVMAFNVGMILGPAVGGAA
LQASSSLPLPVAVRVPFALLPLGALAGLLLIFKLPDVRYKTKMKVRELHAKIKSALYVFFFNAFANGFSAGIFMSVLIIY
IMQYVTSVPIKLSSLVALSGLLGMALASPLMKRLDEFDFTNKLKVAIGLGLLHKLALAAVGLTKSYFILLAILTVQNFAI
TVVIPLIRSLVSDLVPRELTAKVFGMQQAYFNLGMIVGPLVGAALYKWLEASGVGGGLAFPVAAALGAAGVLTLLRVDGR
EVEGMKGEPVKAEG
>Mature_414_residues
MWTKLVALSAIISITFSASNVALPYFLMYLKGELKTLNAELLNASKVALEFGALTSTFMGTRVVIAFLSGYIAERIGMKR
SVVVGLILYLVSGIWLIVTENYWEVLVSRALQGVASAMVWPVAESMIVEFAGGKKTRALMLYVMAFNVGMILGPAVGGAA
LQASSSLPLPVAVRVPFALLPLGALAGLLLIFKLPDVRYKTKMKVRELHAKIKSALYVFFFNAFANGFSAGIFMSVLIIY
IMQYVTSVPIKLSSLVALSGLLGMALASPLMKRLDEFDFTNKLKVAIGLGLLHKLALAAVGLTKSYFILLAILTVQNFAI
TVVIPLIRSLVSDLVPRELTAKVFGMQQAYFNLGMIVGPLVGAALYKWLEASGVGGGLAFPVAAALGAAGVLTLLRVDGR
EVEGMKGEPVKAEG

Specific function: Involved in quinolone resistance. May constitute a membrane-associated active efflux pump of hydrophilic quinolones [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004734
- InterPro:   IPR001958 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44263; Mature: 44263

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWTKLVALSAIISITFSASNVALPYFLMYLKGELKTLNAELLNASKVALEFGALTSTFMG
CCHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRVVIAFLSGYIAERIGMKRSVVVGLILYLVSGIWLIVTENYWEVLVSRALQGVASAMVW
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHH
PVAESMIVEFAGGKKTRALMLYVMAFNVGMILGPAVGGAALQASSSLPLPVAVRVPFALL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCEEHHCCHHHH
PLGALAGLLLIFKLPDVRYKTKMKVRELHAKIKSALYVFFFNAFANGFSAGIFMSVLIIY
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
IMQYVTSVPIKLSSLVALSGLLGMALASPLMKRLDEFDFTNKLKVAIGLGLLHKLALAAV
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
GLTKSYFILLAILTVQNFAITVVIPLIRSLVSDLVPRELTAKVFGMQQAYFNLGMIVGPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
VGAALYKWLEASGVGGGLAFPVAAALGAAGVLTLLRVDGREVEGMKGEPVKAEG
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MWTKLVALSAIISITFSASNVALPYFLMYLKGELKTLNAELLNASKVALEFGALTSTFMG
CCHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRVVIAFLSGYIAERIGMKRSVVVGLILYLVSGIWLIVTENYWEVLVSRALQGVASAMVW
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHH
PVAESMIVEFAGGKKTRALMLYVMAFNVGMILGPAVGGAALQASSSLPLPVAVRVPFALL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCEEHHCCHHHH
PLGALAGLLLIFKLPDVRYKTKMKVRELHAKIKSALYVFFFNAFANGFSAGIFMSVLIIY
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
IMQYVTSVPIKLSSLVALSGLLGMALASPLMKRLDEFDFTNKLKVAIGLGLLHKLALAAV
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
GLTKSYFILLAILTVQNFAITVVIPLIRSLVSDLVPRELTAKVFGMQQAYFNLGMIVGPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
VGAALYKWLEASGVGGGLAFPVAAALGAAGVLTLLRVDGREVEGMKGEPVKAEG
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA